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Items: 1 to 20 of 45

1.

Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons.

Yuan Y, Xie S, Darnell JC, Darnell AJ, Saito Y, Phatnani H, Murphy EA, Zhang C, Maniatis T, Darnell RB.

Genome Biol. 2018 Aug 15;19(1):117. doi: 10.1186/s13059-018-1493-2.

2.

Feasibility of clinical pharmacist-led CYP2C19 genotyping for patients receiving non-emergent cardiac catheterization in an integrated health system.

Johnson SG, Shaw PB, Delate T, Kurz DL, Gregg D, Darnell JC, Aquilante CL.

Pharm Pract (Granada). 2017 Apr-Jun;15(2):946. doi: 10.18549/PharmPract.2017.02.946. Epub 2017 Jun 30.

3.

Erratum: Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis.

Moore MJ, Zhang C, Gantman EC, Mele A, Darnell JC, Darnell RB.

Nat Protoc. 2016 Mar;11(3):616. doi: 10.1038/nprot0316-616c. Epub 2016 Feb 25. No abstract available.

PMID:
26914319
4.

Crystal structure reveals specific recognition of a G-quadruplex RNA by a β-turn in the RGG motif of FMRP.

Vasilyev N, Polonskaia A, Darnell JC, Darnell RB, Patel DJ, Serganov A.

Proc Natl Acad Sci U S A. 2015 Sep 29;112(39):E5391-400. doi: 10.1073/pnas.1515737112. Epub 2015 Sep 15.

5.

Cholesterol levels in fragile X syndrome.

Berry-Kravis E, Levin R, Shah H, Mathur S, Darnell JC, Ouyang B.

Am J Med Genet A. 2015 Feb;167A(2):379-84. doi: 10.1002/ajmg.a.36850. Epub 2014 Nov 25.

6.

Molecular biology. Ribosome rescue and neurodegeneration.

Darnell JC.

Science. 2014 Jul 25;345(6195):378-9. doi: 10.1126/science.1257193. Epub 2014 Jul 24. No abstract available.

PMID:
25061188
7.

Mapping Argonaute and conventional RNA-binding protein interactions with RNA at single-nucleotide resolution using HITS-CLIP and CIMS analysis.

Moore MJ, Zhang C, Gantman EC, Mele A, Darnell JC, Darnell RB.

Nat Protoc. 2014 Feb;9(2):263-93. doi: 10.1038/nprot.2014.012. Epub 2014 Jan 9. Erratum in: Nat Protoc. 2016 Mar;11(3):616.

8.

The translation of translational control by FMRP: therapeutic targets for FXS.

Darnell JC, Klann E.

Nat Neurosci. 2013 Nov;16(11):1530-6. doi: 10.1038/nn.3379. Epub 2013 Apr 14. Review.

9.

Cytoplasmic RNA-binding proteins and the control of complex brain function.

Darnell JC, Richter JD.

Cold Spring Harb Perspect Biol. 2012 Aug 1;4(8):a012344. doi: 10.1101/cshperspect.a012344. Review.

10.

De novo gene disruptions in children on the autistic spectrum.

Iossifov I, Ronemus M, Levy D, Wang Z, Hakker I, Rosenbaum J, Yamrom B, Lee YH, Narzisi G, Leotta A, Kendall J, Grabowska E, Ma B, Marks S, Rodgers L, Stepansky A, Troge J, Andrews P, Bekritsky M, Pradhan K, Ghiban E, Kramer M, Parla J, Demeter R, Fulton LL, Fulton RS, Magrini VJ, Ye K, Darnell JC, Darnell RB, Mardis ER, Wilson RK, Schatz MC, McCombie WR, Wigler M.

Neuron. 2012 Apr 26;74(2):285-99. doi: 10.1016/j.neuron.2012.04.009.

11.

FMRP stalls ribosomal translocation on mRNAs linked to synaptic function and autism.

Darnell JC, Van Driesche SJ, Zhang C, Hung KY, Mele A, Fraser CE, Stone EF, Chen C, Fak JJ, Chi SW, Licatalosi DD, Richter JD, Darnell RB.

Cell. 2011 Jul 22;146(2):247-61. doi: 10.1016/j.cell.2011.06.013.

12.

Defects in translational regulation contributing to human cognitive and behavioral disease.

Darnell JC.

Curr Opin Genet Dev. 2011 Aug;21(4):465-73. doi: 10.1016/j.gde.2011.05.002. Epub 2011 Jul 19. Review.

13.

Protein-RNA and protein-protein recognition by dual KH1/2 domains of the neuronal splicing factor Nova-1.

Teplova M, Malinina L, Darnell JC, Song J, Lu M, Abagyan R, Musunuru K, Teplov A, Burley SK, Darnell RB, Patel DJ.

Structure. 2011 Jul 13;19(7):930-44. doi: 10.1016/j.str.2011.05.002.

14.

Structure-function studies of FMRP RGG peptide recognition of an RNA duplex-quadruplex junction.

Phan AT, Kuryavyi V, Darnell JC, Serganov A, Majumdar A, Ilin S, Raslin T, Polonskaia A, Chen C, Clain D, Darnell RB, Patel DJ.

Nat Struct Mol Biol. 2011 Jun 5;18(7):796-804. doi: 10.1038/nsmb.2064.

15.

A mouse model of the human Fragile X syndrome I304N mutation.

Zang JB, Nosyreva ED, Spencer CM, Volk LJ, Musunuru K, Zhong R, Stone EF, Yuva-Paylor LA, Huber KM, Paylor R, Darnell JC, Darnell RB.

PLoS Genet. 2009 Dec;5(12):e1000758. doi: 10.1371/journal.pgen.1000758. Epub 2009 Dec 11.

16.

Discrimination of common and unique RNA-binding activities among Fragile X mental retardation protein paralogs.

Darnell JC, Fraser CE, Mostovetsky O, Darnell RB.

Hum Mol Genet. 2009 Sep 1;18(17):3164-77. doi: 10.1093/hmg/ddp255. Epub 2009 Jun 1.

17.

HITS-CLIP yields genome-wide insights into brain alternative RNA processing.

Licatalosi DD, Mele A, Fak JJ, Ule J, Kayikci M, Chi SW, Clark TA, Schweitzer AC, Blume JE, Wang X, Darnell JC, Darnell RB.

Nature. 2008 Nov 27;456(7221):464-9. doi: 10.1038/nature07488. Epub 2008 Nov 2.

18.

FMRP RNA targets: identification and validation.

Darnell JC, Mostovetsky O, Darnell RB.

Genes Brain Behav. 2005 Aug;4(6):341-9. Review.

19.

Kissing complex RNAs mediate interaction between the Fragile-X mental retardation protein KH2 domain and brain polyribosomes.

Darnell JC, Fraser CE, Mostovetsky O, Stefani G, Jones TA, Eddy SR, Darnell RB.

Genes Dev. 2005 Apr 15;19(8):903-18. Epub 2005 Apr 1.

20.

Fragile X mental retardation protein is associated with translating polyribosomes in neuronal cells.

Stefani G, Fraser CE, Darnell JC, Darnell RB.

J Neurosci. 2004 Aug 18;24(33):7272-6.

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