Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 52

1.

Inhibition of PARP1-dependent end-joining contributes to Olaparib-mediated radiosensitization in tumor cells.

Kötter A, Cornils K, Borgmann K, Dahm-Daphi J, Petersen C, Dikomey E, Mansour WY.

Mol Oncol. 2014 Dec;8(8):1616-25. doi: 10.1016/j.molonc.2014.06.008. Epub 2014 Jul 1.

2.

Carbon ion radiotherapy of human lung cancer attenuates HIF-1 signaling and acts with considerably enhanced therapeutic efficiency.

Subtil FS, Wilhelm J, Bill V, Westholt N, Rudolph S, Fischer J, Scheel S, Seay U, Fournier C, Taucher-Scholz G, Scholz M, Seeger W, Engenhart-Cabillic R, Rose F, Dahm-Daphi J, Hänze J.

FASEB J. 2014 Mar;28(3):1412-21. doi: 10.1096/fj.13-242230. Epub 2013 Dec 17.

PMID:
24347608
3.

The absence of Ku but not defects in classical non-homologous end-joining is required to trigger PARP1-dependent end-joining.

Mansour WY, Borgmann K, Petersen C, Dikomey E, Dahm-Daphi J.

DNA Repair (Amst). 2013 Dec;12(12):1134-42. doi: 10.1016/j.dnarep.2013.10.005. Epub 2013 Nov 7.

PMID:
24210699
4.

ATM is required for the repair of Topotecan-induced replication-associated double-strand breaks.

Köcher S, Spies-Naumann A, Kriegs M, Dahm-Daphi J, Dornreiter I.

Radiother Oncol. 2013 Sep;108(3):409-14. doi: 10.1016/j.radonc.2013.06.024. Epub 2013 Aug 5.

PMID:
23928469
5.

Residual γH2AX foci predict local tumour control after radiotherapy.

Koch U, Höhne K, von Neubeck C, Thames HD, Yaromina A, Dahm-Daphi J, Baumann M, Krause M.

Radiother Oncol. 2013 Sep;108(3):434-9. doi: 10.1016/j.radonc.2013.06.022. Epub 2013 Jul 25.

PMID:
23891089
6.

Detection of impaired homologous recombination repair in NSCLC cells and tissues.

Birkelbach M, Ferraiolo N, Gheorghiu L, Pfäffle HN, Daly B, Ebright MI, Spencer C, O'Hara C, Whetstine JR, Benes CH, Sequist LV, Zou L, Dahm-Daphi J, Kachnic LA, Willers H.

J Thorac Oncol. 2013 Mar;8(3):279-86. doi: 10.1097/JTO.0b013e31827ecf83.

7.

Aberrant overexpression of miR-421 downregulates ATM and leads to a pronounced DSB repair defect and clinical hypersensitivity in SKX squamous cell carcinoma.

Mansour WY, Bogdanova NV, Kasten-Pisula U, Rieckmann T, Köcher S, Borgmann K, Baumann M, Krause M, Petersen C, Hu H, Gatti RA, Dikomey E, Dörk T, Dahm-Daphi J.

Radiother Oncol. 2013 Jan;106(1):147-54. doi: 10.1016/j.radonc.2012.10.020. Epub 2012 Nov 28.

PMID:
23199656
8.

[Prediction of the reaction of normal tissue and tumor cells to radiotherapy].

Dikomey E, Dahm-Daphi J, Distel L.

Strahlenther Onkol. 2012 Nov;188 Suppl 3:304-7. doi: 10.1007/s00066-012-0204-2. Review. German. No abstract available.

PMID:
22907578
9.

Radiation-induced double-strand breaks require ATM but not Artemis for homologous recombination during S-phase.

Köcher S, Rieckmann T, Rohaly G, Mansour WY, Dikomey E, Dornreiter I, Dahm-Daphi J.

Nucleic Acids Res. 2012 Sep 1;40(17):8336-47. Epub 2012 Jun 22.

10.

Cisplatin resistance induced in germ cell tumour cells is due to reduced susceptibility towards cell death but not to altered DNA damage induction or repair.

Fenske AE, Glaesener S, Bokemeyer C, Thomale J, Dahm-Daphi J, Honecker F, Dartsch DC.

Cancer Lett. 2012 Nov 28;324(2):171-8. doi: 10.1016/j.canlet.2012.05.009. Epub 2012 May 19.

PMID:
22613583
11.

p53 modulates homologous recombination at I-SceI-induced double-strand breaks through cell-cycle regulation.

Rieckmann T, Kriegs M, Nitsch L, Hoffer K, Rohaly G, Kocher S, Petersen C, Dikomey E, Dornreiter I, Dahm-Daphi J.

Oncogene. 2013 Feb 21;32(8):968-75. doi: 10.1038/onc.2012.123. Epub 2012 Apr 9.

PMID:
22484423
12.

ATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells.

Sirbu BM, Lachmayer SJ, Wülfing V, Marten LM, Clarkson KE, Lee LW, Gheorghiu L, Zou L, Powell SN, Dahm-Daphi J, Willers H.

PLoS One. 2011;6(8):e23053. doi: 10.1371/journal.pone.0023053. Epub 2011 Aug 12.

13.

EGF receptor inhibition radiosensitizes NSCLC cells by inducing senescence in cells sustaining DNA double-strand breaks.

Wang M, Morsbach F, Sander D, Gheorghiu L, Nanda A, Benes C, Kriegs M, Krause M, Dikomey E, Baumann M, Dahm-Daphi J, Settleman J, Willers H.

Cancer Res. 2011 Oct 1;71(19):6261-9. doi: 10.1158/0008-5472.CAN-11-0213. Epub 2011 Aug 18.

14.

In tumor cells regulation of DNA double strand break repair through EGF receptor involves both NHEJ and HR and is independent of p53 and K-Ras status.

Myllynen L, Rieckmann T, Dahm-Daphi J, Kasten-Pisula U, Petersen C, Dikomey E, Kriegs M.

Radiother Oncol. 2011 Oct;101(1):147-51. doi: 10.1016/j.radonc.2011.05.046. Epub 2011 Jun 12.

PMID:
21665306
15.

FANCD2 but not FANCA promotes cellular resistance to type II topoisomerase poisons.

Kachnic LA, Li L, Fournier L, Ferraiolo N, Dahm-Daphi J, Borgmann K, Willers H.

Cancer Lett. 2011 Jun 1;305(1):86-93. doi: 10.1016/j.canlet.2011.02.030.

PMID:
21414716
16.

Requirement of ATM-dependent monoubiquitylation of histone H2B for timely repair of DNA double-strand breaks.

Moyal L, Lerenthal Y, Gana-Weisz M, Mass G, So S, Wang SY, Eppink B, Chung YM, Shalev G, Shema E, Shkedy D, Smorodinsky NI, van Vliet N, Kuster B, Mann M, Ciechanover A, Dahm-Daphi J, Kanaar R, Hu MC, Chen DJ, Oren M, Shiloh Y.

Mol Cell. 2011 Mar 4;41(5):529-42. doi: 10.1016/j.molcel.2011.02.015.

17.

The epidermal growth factor receptor modulates DNA double-strand break repair by regulating non-homologous end-joining.

Kriegs M, Kasten-Pisula U, Rieckmann T, Holst K, Saker J, Dahm-Daphi J, Dikomey E.

DNA Repair (Amst). 2010 Aug 5;9(8):889-97. doi: 10.1016/j.dnarep.2010.05.005. Epub 2010 Jun 19.

PMID:
20615764
18.

The alternative end-joining pathway for repair of DNA double-strand breaks requires PARP1 but is not dependent upon microhomologies.

Mansour WY, Rhein T, Dahm-Daphi J.

Nucleic Acids Res. 2010 Oct;38(18):6065-77. doi: 10.1093/nar/gkq387. Epub 2010 May 18.

19.

Targeting DNA double-strand break repair: is it the right way for sensitizing cells to 5-fluorouracil?

El-Awady RA, Saleh EM, Dahm-Daphi J.

Anticancer Drugs. 2010 Mar;21(3):277-87. doi: 10.1097/CAD.0b013e328334b0ae.

PMID:
20075715
20.

The extreme radiosensitivity of the squamous cell carcinoma SKX is due to a defect in double-strand break repair.

Kasten-Pisula U, Menegakis A, Brammer I, Borgmann K, Mansour WY, Degenhardt S, Krause M, Schreiber A, Dahm-Daphi J, Petersen C, Dikomey E, Baumann M.

Radiother Oncol. 2009 Feb;90(2):257-64. doi: 10.1016/j.radonc.2008.10.019. Epub 2008 Nov 27.

PMID:
19038467

Supplemental Content

Loading ...
Support Center