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Items: 1 to 20 of 67

1.

The stress regulator FKBP51 drives chronic pain by modulating spinal glucocorticoid signaling.

Maiarù M, Tochiki KK, Cox MB, Annan LV, Bell CG, Feng X, Hausch F, Géranton SM.

Sci Transl Med. 2016 Feb 10;8(325):325ra19. doi: 10.1126/scitranslmed.aab3376.

2.

Similarities and Distinctions in Actions of Surface-Directed and Classic Androgen Receptor Antagonists.

Suh JH, Chattopadhyay A, Sieglaff DH, Storer Samaniego C, Cox MB, Webb P.

PLoS One. 2015 Sep 2;10(9):e0137103. doi: 10.1371/journal.pone.0137103.

3.

The FKBP52 Cochaperone Acts in Synergy with β-Catenin to Potentiate Androgen Receptor Signaling.

Storer Samaniego C, Suh JH, Chattopadhyay A, Olivares K, Guy N, Sivils JC, Dey P, Yumoto F, Fletterick RJ, Strom AM, Gustafsson JÅ, Webb P, Cox MB.

PLoS One. 2015 Jul 24;10(7):e0134015. doi: 10.1371/journal.pone.0134015.

4.

Therapeutic Targeting of the FKBP52 Co-Chaperone in Steroid Hormone Receptor-Regulated Physiology and Disease.

Guy NC, Garcia YA, Cox MB.

Curr Mol Pharmacol. 2015;9(2):109-25. Review.

PMID:
25986565
5.

Tetratricopeptide repeat domain 9A negatively regulates estrogen receptor alpha activity.

Shrestha S, Sun Y, Lufkin T, Kraus P, Or Y, Garcia YA, Guy N, Ramos P, Cox MB, Tay F, Lin VC.

Int J Biol Sci. 2015 Feb 27;11(4):434-47. doi: 10.7150/ijbs.9311.

6.
7.

Functions of the Hsp90-binding FKBP immunophilins.

Guy NC, Garcia YA, Sivils JC, Galigniana MD, Cox MB.

Subcell Biochem. 2015;78:35-68. doi: 10.1007/978-3-319-11731-7_2. Review.

PMID:
25487015
8.

The Hsp90 ensemble: coordinated Hsp90-cochaperone complexes regulate diverse cellular processes.

Schwenkert S, Hugel T, Cox MB.

Nat Struct Mol Biol. 2014 Dec;21(12):1017-21. doi: 10.1038/nsmb.2927. No abstract available.

PMID:
25469839
9.

A role for synapsin in FKBP51 modulation of stress responsiveness: Convergent evidence from animal and human studies.

Schmidt U, Buell DR, Ionescu IA, Gassen NC, Holsboer F, Cox MB, Novak B, Huber C, Hartmann J, Schmidt MV, Touma C, Rein T, Herrmann L.

Psychoneuroendocrinology. 2015 Feb;52:43-58. doi: 10.1016/j.psyneuen.2014.11.005.

PMID:
25459892
10.

Solution formulation development and efficacy of MJC13 in a preclinical model of castration-resistant prostate cancer.

Liang S, Bian X, Liang D, Sivils JC, Neckers LM, Cox MB, Xie H.

Pharm Dev Technol. 2016;21(1):121-6. doi: 10.3109/10837450.2014.979946.

11.

Bioavailability and fate of sediment-associated trenbolone and estradiol in aquatic systems.

Sangster JL, Zhang Y, Hernandez R, Garcia YA, Sivils JC, Cox MB, Snow DD, Kolok AS, Bartelt-Hunt SL.

Sci Total Environ. 2014 Oct 15;496:576-84. doi: 10.1016/j.scitotenv.2014.07.040.

PMID:
25108798
12.

NF-κB transcriptional activity is modulated by FK506-binding proteins FKBP51 and FKBP52: a role for peptidyl-prolyl isomerase activity.

Erlejman AG, De Leo SA, Mazaira GI, Molinari AM, Camisay MF, Fontana V, Cox MB, Piwien-Pilipuk G, Galigniana MD.

J Biol Chem. 2014 Sep 19;289(38):26263-76. doi: 10.1074/jbc.M114.582882.

13.

Affinity purification probes of potential use to investigate the endogenous Hsp70 interactome in cancer.

Rodina A, Taldone T, Kang Y, Patel PD, Koren J 3rd, Yan P, DaGama Gomes EM, Yang C, Patel MR, Shrestha L, Ochiana SO, Santarossa C, Maharaj R, Gozman A, Cox MB, Erdjument-Bromage H, Hendrickson RC, Cerchietti L, Melnick A, Guzman ML, Chiosis G.

ACS Chem Biol. 2014 Aug 15;9(8):1698-705. doi: 10.1021/cb500256u.

14.

The cochaperone SGTA (small glutamine-rich tetratricopeptide repeat-containing protein alpha) demonstrates regulatory specificity for the androgen, glucocorticoid, and progesterone receptors.

Paul A, Garcia YA, Zierer B, Patwardhan C, Gutierrez O, Hildenbrand Z, Harris DC, Balsiger HA, Sivils JC, Johnson JL, Buchner J, Chadli A, Cox MB.

J Biol Chem. 2014 May 30;289(22):15297-308. doi: 10.1074/jbc.M113.535229.

15.

Molecular chaperone activity and biological regulatory actions of the TPR-domain immunophilins FKBP51 and FKBP52.

Erlejman AG, Lagadari M, Harris DC, Cox MB, Galigniana MD.

Curr Protein Pept Sci. 2014 May;15(3):205-15. Review.

PMID:
24694367
16.

Emergency department visit rates and patterns in Canada's Vancouver coastal health region.

McGregor MJ, McGrail KM, Abu-Laban RB, Ronald LA, Baumbusch J, Andrusiek D, Cox MB.

Can J Aging. 2014 Jun;33(2):154-62. doi: 10.1017/S0714980814000038.

PMID:
24690211
17.

Coregulator control of androgen receptor action by a novel nuclear receptor-binding motif.

Jehle K, Cato L, Neeb A, Muhle-Goll C, Jung N, Smith EW, Buzon V, Carbó LR, Estébanez-Perpiñá E, Schmitz K, Fruk L, Luy B, Chen Y, Cox MB, Bräse S, Brown M, Cato AC.

J Biol Chem. 2014 Mar 28;289(13):8839-51. doi: 10.1074/jbc.M113.534859.

18.

Nursing home characteristics associated with resident transfers to emergency departments.

McGregor MJ, Abu-Laban RB, Ronald LA, McGrail KM, Andrusiek D, Baumbusch J, Cox MB, Salomons K, Schulzer M, Kuramoto L.

Can J Aging. 2014 Mar;33(1):38-48. doi: 10.1017/S0714980813000615.

PMID:
24398137
19.

Common genetic variants in the plasminogen activation pathway are not associated with multiple sclerosis.

Cox MB, Bowden NA, Scott RJ, Lechner-Scott J.

Mult Scler. 2014 Apr;20(4):489-91. doi: 10.1177/1352458513498127.

PMID:
23897640
20.
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