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Molecular Assessment of C4d-Positive Renal Transplant Biopsies Without Evidence of Rejection.

Dominy KM, Willicombe M, Al Johani T, Beckwith H, Goodall D, Brookes P, Cook HT, Cairns T, McLean A, Roufosse C.

Kidney Int Rep. 2018 Sep 18;4(1):148-158. doi: 10.1016/j.ekir.2018.09.005. eCollection 2019 Jan.


Reproducibility of the Oxford classification of immunoglobulin A nephropathy, impact of biopsy scoring on treatment allocation and clinical relevance of disagreements: evidence from the VALidation of IGA study cohort.

Bellur SS, Roberts ISD, Troyanov S, Royal V, Coppo R, Cook HT, Cattran D, Arce Terroba Y, Asunis AM, Bajema I, Bertoni E, Bruijn JA, Cannata-Ortiz P, Casartelli D, Maria Di Palma A, Ferrario F, Fortunato M, Furci L, Gakiopoulou H, Galesic Ljubanovic D, Giannakakis K, Gomà M, Gröne HJ, Gutiérrez EM, Asma Haider S, Honsova E, Ioachim E, Karkoszka H, Kipgen D, Maldyk J, Mazzucco G, Orhan D, Ozluk Y, Pantzaki A, Perkowska-Ptasinska A, Riispere Z, Soderberg MP, Steenbergen E, Stoppacciaro A, Sundelin Von Feilitzen B, Tardanico R.

Nephrol Dial Transplant. 2018 Dec 15. doi: 10.1093/ndt/gfy337. [Epub ahead of print]


Progressive IgA Nephropathy Is Associated With Low Circulating Mannan-Binding Lectin-Associated Serine Protease-3 (MASP-3) and Increased Glomerular Factor H-Related Protein-5 (FHR5) Deposition.

Medjeral-Thomas NR, Troldborg A, Constantinou N, Lomax-Browne HJ, Hansen AG, Willicombe M, Pusey CD, Cook HT, Thiel S, Pickering MC.

Kidney Int Rep. 2017 Nov 29;3(2):426-438. doi: 10.1016/j.ekir.2017.11.015. eCollection 2018 Mar.


Distribution of exogenous complement factor H in mice in vivo.

Koskinen AR, Cheng ZZ, Pickering MC, Kairemo K, Meri T, Cook HT, Meri S, Jokiranta TS.

Scand J Immunol. 2018 Jul;88(1):e12671. doi: 10.1111/sji.12671. Epub 2018 May 23.


RIPK3-deficient mice were not protected from nephrotoxic nephritis.

Hill NR, Cook HT, Pusey CD, Tarzi RM.

BMC Nephrol. 2018 Mar 14;19(1):61. doi: 10.1186/s12882-018-0850-4.


Evolving complexity of complement-related diseases: C3 glomerulopathy and atypical haemolytic uremic syndrome.

Cook HT.

Curr Opin Nephrol Hypertens. 2018 May;27(3):165-170. doi: 10.1097/MNH.0000000000000412.


Revision of the International Society of Nephrology/Renal Pathology Society classification for lupus nephritis: clarification of definitions, and modified National Institutes of Health activity and chronicity indices.

Bajema IM, Wilhelmus S, Alpers CE, Bruijn JA, Colvin RB, Cook HT, D'Agati VD, Ferrario F, Haas M, Jennette JC, Joh K, Nast CC, Noël LH, Rijnink EC, Roberts ISD, Seshan SV, Sethi S, Fogo AB.

Kidney Int. 2018 Apr;93(4):789-796. doi: 10.1016/j.kint.2017.11.023. Epub 2018 Feb 16.


A triglyceride-rich lipoprotein environment exacerbates renal injury in the accelerated nephrotoxic nephritis model.

Saja MF, Cook HT, Ruseva MM, Szajna M, Pickering MC, Woollard KJ, Botto M.

Clin Exp Immunol. 2018 Jun;192(3):337-347. doi: 10.1111/cei.13111. Epub 2018 Mar 9.


Clusters Not Classifications: Making Sense of Complement-Mediated Kidney Injury.

Cook HT, Pickering MC.

J Am Soc Nephrol. 2018 Jan;29(1):9-12. doi: 10.1681/ASN.2017111183. Epub 2017 Dec 11. No abstract available.


Positive antineutrophil cytoplasmic antibody serology in patients with lupus nephritis is associated with distinct histopathologic features on renal biopsy.

Turner-Stokes T, Wilson HR, Morreale M, Nunes A, Cairns T, Cook HT, Pusey CD, Tarzi RM, Lightstone L.

Kidney Int. 2017 Nov;92(5):1223-1231. doi: 10.1016/j.kint.2017.04.029. Epub 2017 Jul 24.


Circulating complement factor H-related proteins 1 and 5 correlate with disease activity in IgA nephropathy.

Medjeral-Thomas NR, Lomax-Browne HJ, Beckwith H, Willicombe M, McLean AG, Brookes P, Pusey CD, Falchi M, Cook HT, Pickering MC.

Kidney Int. 2017 Oct;92(4):942-952. doi: 10.1016/j.kint.2017.03.043. Epub 2017 Jun 30.


Identification of Ceruloplasmin as a Gene that Affects Susceptibility to Glomerulonephritis Through Macrophage Function.

Chen TD, Rotival M, Chiu LY, Bagnati M, Ko JH, Srivastava PK, Petretto E, Pusey CD, Lai PC, Aitman TJ, Cook HT, Behmoaras J.

Genetics. 2017 Jun;206(2):1139-1151. doi: 10.1534/genetics.116.197376. Epub 2017 Apr 26.


Long-term outcome in biopsy-proven acute interstitial nephritis treated with steroids.

Prendecki M, Tanna A, Salama AD, Tam FW, Cairns T, Taube D, Cook HT, Ashby D, Duncan ND, Pusey CD.

Clin Kidney J. 2017 Apr;10(2):233-239. doi: 10.1093/ckj/sfw116. Epub 2016 Dec 24.


Mycophenolate mofetil therapy in immunoglobulin A nephropathy: histological changes after treatment.

Beckwith H, Medjeral-Thomas N, Galliford J, Griffith M, Levy J, Lightstone L, Palmer A, Roufosse C, Pusey C, Cook HT, Cairns T.

Nephrol Dial Transplant. 2017 Jan 1;32(suppl_1):i123-i128. doi: 10.1093/ndt/gfw326.


Altered expression of signalling lymphocyte activation molecule receptors in T-cells from lupus nephritis patients-a potential biomarker of disease activity.

Stratigou V, Doyle AF, Carlucci F, Stephens L, Foschi V, Castelli M, McKenna N, Cook HT, Lightstone L, Cairns TD, Pickering MC, Botto M.

Rheumatology (Oxford). 2017 Jul 1;56(7):1206-1216. doi: 10.1093/rheumatology/kex078.


C3 glomerulopathy.

Cook HT.

F1000Res. 2017 Mar 10;6:248. doi: 10.12688/f1000research.10364.1. eCollection 2017. Review.


Oxford Classification of IgA nephropathy 2016: an update from the IgA Nephropathy Classification Working Group.

Trimarchi H, Barratt J, Cattran DC, Cook HT, Coppo R, Haas M, Liu ZH, Roberts IS, Yuzawa Y, Zhang H, Feehally J; IgAN Classification Working Group of the International IgA Nephropathy Network and the Renal Pathology Society; Conference Participants.

Kidney Int. 2017 May;91(5):1014-1021. doi: 10.1016/j.kint.2017.02.003. Epub 2017 Mar 22. Review.


A proposal for standardized grading of chronic changes in native kidney biopsy specimens.

Sethi S, D'Agati VD, Nast CC, Fogo AB, De Vriese AS, Markowitz GS, Glassock RJ, Fervenza FC, Seshan SV, Rule A, Racusen LC, Radhakrishnan J, Winearls CG, Appel GB, Bajema IM, Chang A, Colvin RB, Cook HT, Hariharan S, Herrera Hernandez LP, Kambham N, Mengel M, Nath KA, Rennke HG, Ronco P, Rovin BH, Haas M.

Kidney Int. 2017 Apr;91(4):787-789. doi: 10.1016/j.kint.2017.01.002.


Atypical hemolytic uremic syndrome and C3 glomerulopathy: conclusions from a "Kidney Disease: Improving Global Outcomes" (KDIGO) Controversies Conference.

Goodship TH, Cook HT, Fakhouri F, Fervenza FC, Frémeaux-Bacchi V, Kavanagh D, Nester CM, Noris M, Pickering MC, Rodríguez de Córdoba S, Roumenina LT, Sethi S, Smith RJ; Conference Participants.

Kidney Int. 2017 Mar;91(3):539-551. doi: 10.1016/j.kint.2016.10.005. Epub 2016 Dec 16.


A Multicenter Cohort Study of Histologic Findings and Long-Term Outcomes of Kidney Disease in Women Who Have Been Pregnant.

Webster P, Webster LM, Cook HT, Horsfield C, Seed PT, Vaz R, Santos C, Lydon I, Homsy M, Lightstone L, Bramham K.

Clin J Am Soc Nephrol. 2017 Mar 7;12(3):408-416. doi: 10.2215/CJN.05610516. Epub 2016 Dec 9.

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