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Items: 1 to 20 of 575

1.

Drug and disease signature integration identifies synergistic combinations in glioblastoma.

Stathias V, Jermakowicz AM, Maloof ME, Forlin M, Walters W, Suter RK, Durante MA, Williams SL, Harbour JW, Volmar CH, Lyons NJ, Wahlestedt C, Graham RM, Ivan ME, Komotar RJ, Sarkaria JN, Subramanian A, Golub TR, Schürer SC, Ayad NG.

Nat Commun. 2018 Dec 14;9(1):5315. doi: 10.1038/s41467-018-07659-z.

2.

Genomics of aggressive B-cell lymphoma.

Rosenthal A, Rimsza L.

Hematology Am Soc Hematol Educ Program. 2018 Nov 30;2018(1):69-74. doi: 10.1182/asheducation-2018.1.69. Review.

PMID:
30504293
3.

Characterization of farnesyl diphosphate farnesyl transferase 1 (FDFT1) expression in cancer.

Tüzmen Ş, Hostetter G, Watanabe A, Ekmekçi C, Carrigan PE, Shechter I, Kallioniemi O, Miller LJ, Mousses S.

Per Med. 2019 Jan;16(1):51-65. doi: 10.2217/pme-2016-0058. Epub 2018 Nov 23.

PMID:
30468409
4.

Laboratory analysis of amino acids, 2018 revision: a technical standard of the American College of Medical Genetics and Genomics (ACMG).

Sharer JD, De Biase I, Matern D, Young S, Bennett MJ, Tolun AA; ACMG Laboratory Quality Assurance Committee.

Genet Med. 2018 Dec;20(12):1499-1507. doi: 10.1038/s41436-018-0328-6. Epub 2018 Oct 19.

PMID:
30459394
5.

Clustering the autisms using glutamate synapse protein interaction networks from cortical and hippocampal tissue of seven mouse models.

Brown EA, Lautz JD, Davis TR, Gniffke EP, VanSchoiack AAW, Neier SC, Tashbook N, Nicolini C, Fahnestock M, Schrum AG, Smith SEP.

Mol Autism. 2018 Sep 15;9:48. doi: 10.1186/s13229-018-0229-1. eCollection 2018.

6.

Integrating Genomics Into Neuro-Oncology Clinical Trials and Practice.

Galanis E, Nassiri F, Coy S, Nejad R, Zadeh G, Santagata S.

Am Soc Clin Oncol Educ Book. 2018 May 23;(38):148-157. doi: 10.1200/EDBK_200989. Review.

PMID:
30231374
7.

A PDGFRα-driven mouse model of glioblastoma reveals a stathmin1-mediated mechanism of sensitivity to vinblastine.

Jun HJ, Appleman VA, Wu HJ, Rose CM, Pineda JJ, Yeo AT, Delcuze B, Lee C, Gyuris A, Zhu H, Woolfenden S, Bronisz A, Nakano I, Chiocca EA, Bronson RT, Ligon KL, Sarkaria JN, Gygi SP, Michor F, Mitchison TJ, Charest A.

Nat Commun. 2018 Aug 6;9(1):3116. doi: 10.1038/s41467-018-05036-4.

8.

Identification of usual interstitial pneumonia pattern using RNA-Seq and machine learning: challenges and solutions.

Choi Y, Liu TT, Pankratz DG, Colby TV, Barth NM, Lynch DA, Walsh PS, Raghu G, Kennedy GC, Huang J.

BMC Genomics. 2018 May 9;19(Suppl 2):101. doi: 10.1186/s12864-018-4467-6.

9.

Clinical Significance of PTEN Deletion, Mutation, and Loss of PTEN Expression in De Novo Diffuse Large B-Cell Lymphoma.

Wang X, Cao X, Sun R, Tang C, Tzankov A, Zhang J, Manyam GC, Xiao M, Miao Y, Jabbar K, Tan X, Pang Y, Visco C, Xie Y, Dybkaer K, Chiu A, Orazi A, Zu Y, Bhagat G, Richards KL, Hsi ED, Choi WWL, van Krieken JH, Huh J, Ponzoni M, Ferreri AJM, Møller MB, Parsons BM, Winter JN, Piris MA, Li S, Miranda RN, Medeiros LJ, Li Y, Xu-Monette ZY, Young KH.

Neoplasia. 2018 Jun;20(6):574-593. doi: 10.1016/j.neo.2018.03.002. Epub 2018 May 4.

10.

Identification of missing variants by combining multiple analytic pipelines.

Ren Y, Reddy JS, Pottier C, Sarangi V, Tian S, Sinnwell JP, McDonnell SK, Biernacka JM, Carrasquillo MM, Ross OA, Ertekin-Taner N, Rademakers R, Hudson M, Mainzer LS, Asmann YW.

BMC Bioinformatics. 2018 Apr 16;19(1):139. doi: 10.1186/s12859-018-2151-0.

11.

Metabolomics driven analysis by UAEGC-MS and antioxidant activity of chia (Salvia hispanica L.) commercial and mutant seeds.

de Falco B, Fiore A, Rossi R, Amato M, Lanzotti V.

Food Chem. 2018 Jul 15;254:137-143. doi: 10.1016/j.foodchem.2018.01.189. Epub 2018 Feb 2.

PMID:
29548434
12.

Transcriptomic signatures of cellular and humoral immune responses in older adults after seasonal influenza vaccination identified by data-driven clustering.

Voigt EA, Grill DE, Zimmermann MT, Simon WL, Ovsyannikova IG, Kennedy RB, Poland GA.

Sci Rep. 2018 Jan 15;8(1):739. doi: 10.1038/s41598-017-17735-x.

13.

Beta-defensin 1, aryl hydrocarbon receptor and plasma kynurenine in major depressive disorder: metabolomics-informed genomics.

Liu D, Ray B, Neavin DR, Zhang J, Athreya AP, Biernacka JM, Bobo WV, Hall-Flavin DK, Skime MK, Zhu H, Jenkins GD, Batzler A, Kalari KR, Boakye-Agyeman F, Matson WR, Bhasin SS, Mushiroda T, Nakamura Y, Kubo M, Iyer RK, Wang L, Frye MA, Kaddurah-Daouk R, Weinshilboum RM.

Transl Psychiatry. 2018 Jan 10;8(1):10. doi: 10.1038/s41398-017-0056-8.

14.

Genomic correlates of response to immune checkpoint therapies in clear cell renal cell carcinoma.

Miao D, Margolis CA, Gao W, Voss MH, Li W, Martini DJ, Norton C, Bossé D, Wankowicz SM, Cullen D, Horak C, Wind-Rotolo M, Tracy A, Giannakis M, Hodi FS, Drake CG, Ball MW, Allaf ME, Snyder A, Hellmann MD, Ho T, Motzer RJ, Signoretti S, Kaelin WG Jr, Choueiri TK, Van Allen EM.

Science. 2018 Feb 16;359(6377):801-806. doi: 10.1126/science.aan5951. Epub 2018 Jan 4.

15.

Genome-wide meta-analyses identifies novel taxane-induced peripheral neuropathy-associated loci.

Sucheston-Campbell LE, Clay-Gilmour AI, Barlow WE, Budd GT, Stram DO, Haiman CA, Sheng X, Yan L, Zirpoli G, Yao S, Jiang C, Owzar K, Hershman D, Albain KS, Hayes DF, Moore HC, Hobday TJ, Stewart JA, Rizvi A, Isaacs C, Salim M, Gralow JR, Hortobagyi GN, Livingston RB, Kroetz DL, Ambrosone CB.

Pharmacogenet Genomics. 2018 Feb;28(2):49-55. doi: 10.1097/FPC.0000000000000318.

PMID:
29278617
16.

Hybrid-denovo: a de novo OTU-picking pipeline integrating single-end and paired-end 16S sequence tags.

Chen X, Johnson S, Jeraldo P, Wang J, Chia N, Kocher JA, Chen J.

Gigascience. 2018 Mar 1;7(3):1-7. doi: 10.1093/gigascience/gix129.

17.

Discovery of Surface Target Proteins Linking Drugs, Molecular Markers, Gene Regulation, Protein Networks, and Disease by Using a Web-Based Platform Targets-search.

Yan B, Wang P, Wang J, Boheler KR.

Methods Mol Biol. 2018;1722:331-344. doi: 10.1007/978-1-4939-7553-2_19.

PMID:
29264813
18.

Technical Advances for the Clinical Genomic Evaluation of Sudden Cardiac Death: Verification of Next-Generation Sequencing Panels for Hereditary Cardiovascular Conditions Using Formalin-Fixed Paraffin-Embedded Tissues and Dried Blood Spots.

Baudhuin LM, Leduc C, Train LJ, Avula R, Kluge ML, Kotzer KE, Lin PT, Ackerman MJ, Maleszewski JJ.

Circ Cardiovasc Genet. 2017 Dec;10(6). pii: e001844. doi: 10.1161/CIRCGENETICS.117.001844.

PMID:
29237689
19.

Programming Morphogenesis through Systems and Synthetic Biology.

Velazquez JJ, Su E, Cahan P, Ebrahimkhani MR.

Trends Biotechnol. 2018 Apr;36(4):415-429. doi: 10.1016/j.tibtech.2017.11.003. Epub 2017 Dec 8. Review.

PMID:
29229492
20.

Comprehensive Mapping of Pluripotent Stem Cell Metabolism Using Dynamic Genome-Scale Network Modeling.

Chandrasekaran S, Zhang J, Sun Z, Zhang L, Ross CA, Huang YC, Asara JM, Li H, Daley GQ, Collins JJ.

Cell Rep. 2017 Dec 5;21(10):2965-2977. doi: 10.1016/j.celrep.2017.07.048.

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