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Items: 1 to 20 of 253

1.

Isomeric Tuning Yields Bright and Targetable Red Ca2+ Indicators.

Deo C, Sheu SH, Seo J, Clapham DE, Lavis LD.

J Am Chem Soc. 2019 Sep 4;141(35):13734-13738. doi: 10.1021/jacs.9b06092. Epub 2019 Aug 23.

PMID:
31430138
2.

Cryo-EM structure of TRPC5 at 2.8-Å resolution reveals unique and conserved structural elements essential for channel function.

Duan J, Li J, Chen GL, Ge Y, Liu J, Xie K, Peng X, Zhou W, Zhong J, Zhang Y, Xu J, Xue C, Liang B, Zhu L, Liu W, Zhang C, Tian XL, Wang J, Clapham DE, Zeng B, Li Z, Zhang J.

Sci Adv. 2019 Jul 24;5(7):eaaw7935. doi: 10.1126/sciadv.aaw7935. eCollection 2019 Jul.

3.

Structure of the mammalian TRPM7, a magnesium channel required during embryonic development.

Duan J, Li Z, Li J, Hulse RE, Santa-Cruz A, Valinsky WC, Abiria SA, Krapivinsky G, Zhang J, Clapham DE.

Proc Natl Acad Sci U S A. 2018 Aug 28;115(35):E8201-E8210. doi: 10.1073/pnas.1810719115. Epub 2018 Aug 14.

4.

Structure of the mouse TRPC4 ion channel.

Duan J, Li J, Zeng B, Chen GL, Peng X, Zhang Y, Wang J, Clapham DE, Li Z, Zhang J.

Nat Commun. 2018 Aug 6;9(1):3102. doi: 10.1038/s41467-018-05247-9.

5.

Cryo-EM structure of the polycystin 2-l1 ion channel.

Hulse RE, Li Z, Huang RK, Zhang J, Clapham DE.

Elife. 2018 Jul 13;7. pii: e36931. doi: 10.7554/eLife.36931.

6.

Influences: Short circuits.

Clapham DE.

J Gen Physiol. 2018 Apr 2;150(4):513-515. doi: 10.1085/jgp.201812034. Epub 2018 Mar 20. No abstract available.

7.

Structure of full-length human TRPM4.

Duan J, Li Z, Li J, Santa-Cruz A, Sanchez-Martinez S, Zhang J, Clapham DE.

Proc Natl Acad Sci U S A. 2018 Mar 6;115(10):2377-2382. doi: 10.1073/pnas.1722038115. Epub 2018 Feb 20.

8.

Polycystin-2 is an essential ion channel subunit in the primary cilium of the renal collecting duct epithelium.

Liu X, Vien T, Duan J, Sheu SH, DeCaen PG, Clapham DE.

Elife. 2018 Feb 14;7. pii: e33183. doi: 10.7554/eLife.33183.

9.

Histone phosphorylation by TRPM6's cleaved kinase attenuates adjacent arginine methylation to regulate gene expression.

Krapivinsky G, Krapivinsky L, Renthal NE, Santa-Cruz A, Manasian Y, Clapham DE.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7092-E7100. doi: 10.1073/pnas.1708427114. Epub 2017 Aug 7.

10.

TRPM7 senses oxidative stress to release Zn2+ from unique intracellular vesicles.

Abiria SA, Krapivinsky G, Sah R, Santa-Cruz AG, Chaudhuri D, Zhang J, Adstamongkonkul P, DeCaen PG, Clapham DE.

Proc Natl Acad Sci U S A. 2017 Jul 25;114(30):E6079-E6088. doi: 10.1073/pnas.1707380114. Epub 2017 Jul 10.

11.

CatSperζ regulates the structural continuity of sperm Ca2+ signaling domains and is required for normal fertility.

Chung JJ, Miki K, Kim D, Shim SH, Shi HF, Hwang JY, Cai X, Iseri Y, Zhuang X, Clapham DE.

Elife. 2017 Feb 23;6. pii: e23082. doi: 10.7554/eLife.23082.

12.

Leucine-rich repeat containing 8A (LRRC8A)-dependent volume-regulated anion channel activity is dispensable for T-cell development and function.

Platt CD, Chou J, Houlihan P, Badran YR, Kumar L, Bainter W, Poliani PL, Perez CJ, Dent SYR, Clapham DE, Benavides F, Geha RS.

J Allergy Clin Immunol. 2017 Dec;140(6):1651-1659.e1. doi: 10.1016/j.jaci.2016.12.974. Epub 2017 Feb 10.

13.

Progress in ciliary ion channel physiology.

Pablo JL, DeCaen PG, Clapham DE.

J Gen Physiol. 2017 Jan;149(1):37-47. doi: 10.1085/jgp.201611696. Epub 2016 Dec 20. Review.

14.

The Structure of the Polycystic Kidney Disease Channel PKD2 in Lipid Nanodiscs.

Shen PS, Yang X, DeCaen PG, Liu X, Bulkley D, Clapham DE, Cao E.

Cell. 2016 Oct 20;167(3):763-773.e11. doi: 10.1016/j.cell.2016.09.048.

15.

Atypical calcium regulation of the PKD2-L1 polycystin ion channel.

DeCaen PG, Liu X, Abiria S, Clapham DE.

Elife. 2016 Jun 27;5. pii: e13413. doi: 10.7554/eLife.13413.

16.

Primary cilia are not calcium-responsive mechanosensors.

Delling M, Indzhykulian AA, Liu X, Li Y, Xie T, Corey DP, Clapham DE.

Nature. 2016 Mar 31;531(7596):656-60. doi: 10.1038/nature17426. Epub 2016 Mar 23.

17.

Mitochondrial calcium uniporter regulator 1 (MCUR1) regulates the calcium threshold for the mitochondrial permeability transition.

Chaudhuri D, Artiga DJ, Abiria SA, Clapham DE.

Proc Natl Acad Sci U S A. 2016 Mar 29;113(13):E1872-80. doi: 10.1073/pnas.1602264113. Epub 2016 Mar 14.

18.

Molecular basis of ion permeability in a voltage-gated sodium channel.

Naylor CE, Bagnéris C, DeCaen PG, Sula A, Scaglione A, Clapham DE, Wallace BA.

EMBO J. 2016 Apr 15;35(8):820-30. doi: 10.15252/embj.201593285. Epub 2016 Feb 12.

19.

Naturally Produced Defensive Alkenal Compounds Activate TRPA1.

Blair NT, Philipson BI, Richards PM, Doerner JF, Segura A, Silver WL, Clapham DE.

Chem Senses. 2016 May;41(4):281-92. doi: 10.1093/chemse/bjv071. Epub 2016 Feb 3.

20.

The Fungal Sexual Pheromone Sirenin Activates the Human CatSper Channel Complex.

Syeda SS, Carlson EJ, Miller MR, Francis R, Clapham DE, Lishko PV, Hawkinson JE, Hook D, Georg GI.

ACS Chem Biol. 2016 Feb 19;11(2):452-9. doi: 10.1021/acschembio.5b00748. Epub 2015 Dec 16.

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