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Items: 1 to 20 of 103

1.

HBO1 is required for the maintenance of leukaemia stem cells.

MacPherson L, Anokye J, Yeung MM, Lam EYN, Chan YC, Weng CF, Yeh P, Knezevic K, Butler MS, Hoegl A, Chan KL, Burr ML, Gearing LJ, Willson T, Liu J, Choi J, Yang Y, Bilardi RA, Falk H, Nguyen N, Stupple PA, Peat TS, Zhang M, de Silva M, Carrasco-Pozo C, Avery VM, Khoo PS, Dolezal O, Dennis ML, Nuttall S, Surjadi R, Newman J, Ren B, Leaver DJ, Sun Y, Baell JB, Dovey O, Vassiliou GS, Grebien F, Dawson SJ, Street IP, Monahan BJ, Burns CJ, Choudhary C, Blewitt ME, Voss AK, Thomas T, Dawson MA.

Nature. 2019 Dec 11. doi: 10.1038/s41586-019-1835-6. [Epub ahead of print]

PMID:
31827282
2.

Analysis and Interpretation of Protein Post-Translational Modification Site Stoichiometry.

Prus G, Hoegl A, Weinert BT, Choudhary C.

Trends Biochem Sci. 2019 Nov;44(11):943-960. doi: 10.1016/j.tibs.2019.06.003. Epub 2019 Jul 8. Review.

PMID:
31296352
3.

Author Correction: Functions and mechanisms of non-histone protein acetylation.

Narita T, Weinert BT, Choudhary C.

Nat Rev Mol Cell Biol. 2019 Aug;20(8):508. doi: 10.1038/s41580-019-0156-9.

PMID:
31267066
4.

Retraction.

Kaidi A, Weinert BT, Choudhary C, Jackson SP.

Science. 2019 Apr 19;364(6437):247. doi: 10.1126/science.aax4558. Epub 2019 Apr 11. No abstract available.

5.

THE EFFECT OF RALOXIFENE ON SERUM PROLACTIN LEVEL IN PATIENTS WITH PROLACTINOMA.

Choudhary C, Hamrahian AH, Bena JF, Recinos P, Kennedy L, Dobri G.

Endocr Pract. 2019 Jul;25(7):684-688. doi: 10.4158/EP-2018-0321. Epub 2019 Mar 13.

PMID:
30865525
6.

Analysis of human acetylation stoichiometry defines mechanistic constraints on protein regulation.

Hansen BK, Gupta R, Baldus L, Lyon D, Narita T, Lammers M, Choudhary C, Weinert BT.

Nat Commun. 2019 Mar 5;10(1):1055. doi: 10.1038/s41467-019-09024-0.

7.

Acetylation of intrinsically disordered regions regulates phase separation.

Saito M, Hess D, Eglinger J, Fritsch AW, Kreysing M, Weinert BT, Choudhary C, Matthias P.

Nat Chem Biol. 2019 Jan;15(1):51-61. doi: 10.1038/s41589-018-0180-7. Epub 2018 Dec 10.

PMID:
30531905
8.

Deletion of APC7 or APC16 Allows Proliferation of Human Cells without the Spindle Assembly Checkpoint.

Wild T, Budzowska M, Hellmuth S, Eibes S, Karemore G, Barisic M, Stemmann O, Choudhary C.

Cell Rep. 2018 Nov 27;25(9):2317-2328.e5. doi: 10.1016/j.celrep.2018.10.104.

9.

Functions and mechanisms of non-histone protein acetylation.

Narita T, Weinert BT, Choudhary C.

Nat Rev Mol Cell Biol. 2019 Mar;20(3):156-174. doi: 10.1038/s41580-018-0081-3. Review. Erratum in: Nat Rev Mol Cell Biol. 2019 Aug;20(8):508.

PMID:
30467427
10.

STK3 is a therapeutic target for a subset of acute myeloid leukemias.

Camgoz A, Paszkowski-Rogacz M, Satpathy S, Wermke M, Hamann MV, von Bonin M, Choudhary C, Knapp S, Buchholz F.

Oncotarget. 2018 May 22;9(39):25458-25473. doi: 10.18632/oncotarget.25238. eCollection 2018 May 22.

11.

Time-Resolved Analysis Reveals Rapid Dynamics and Broad Scope of the CBP/p300 Acetylome.

Weinert BT, Narita T, Satpathy S, Srinivasan B, Hansen BK, Schölz C, Hamilton WB, Zucconi BE, Wang WW, Liu WR, Brickman JM, Kesicki EA, Lai A, Bromberg KD, Cole PA, Choudhary C.

Cell. 2018 Jun 28;174(1):231-244.e12. doi: 10.1016/j.cell.2018.04.033. Epub 2018 May 24.

12.

Author Correction: Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.

Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T, Faivre E, Ferguson D, Buchanan FG, Martin RL, Torrent M, Chiang GG, Karukurichi K, Langston JW, Weinert BT, Choudhary C, de Vries P, Kluge AF, Patane MA, Van Drie JH, Wang C, McElligott D, Kesicki EA, Marmorstein R, Sun C, Cole PA, Rosenberg SH, Michaelides MR, Lai A, Bromberg KD.

Nature. 2018 Jun;558(7710):E1. doi: 10.1038/s41586-018-0111-5.

PMID:
29769713
13.

DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.

Gupta R, Somyajit K, Narita T, Maskey E, Stanlie A, Kremer M, Typas D, Lammers M, Mailand N, Nussenzweig A, Lukas J, Choudhary C.

Cell. 2018 May 3;173(4):972-988.e23. doi: 10.1016/j.cell.2018.03.050. Epub 2018 Apr 12.

14.

p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage.

Borisova ME, Voigt A, Tollenaere MAX, Sahu SK, Juretschke T, Kreim N, Mailand N, Choudhary C, Bekker-Jensen S, Akutsu M, Wagner SA, Beli P.

Nat Commun. 2018 Mar 9;9(1):1017. doi: 10.1038/s41467-018-03417-3.

15.

lncRNA Panct1 Maintains Mouse Embryonic Stem Cell Identity by Regulating TOBF1 Recruitment to Oct-Sox Sequences in Early G1.

Chakraborty D, Paszkowski-Rogacz M, Berger N, Ding L, Mircetic J, Fu J, Iesmantavicius V, Choudhary C, Anastassiadis K, Stewart AF, Buchholz F.

Cell Rep. 2017 Dec 12;21(11):3012-3021. doi: 10.1016/j.celrep.2017.11.045.

16.

Redox-sensitive alteration of replisome architecture safeguards genome integrity.

Somyajit K, Gupta R, Sedlackova H, Neelsen KJ, Ochs F, Rask MB, Choudhary C, Lukas J.

Science. 2017 Nov 10;358(6364):797-802. doi: 10.1126/science.aao3172.

PMID:
29123070
17.

Discovery of a selective catalytic p300/CBP inhibitor that targets lineage-specific tumours.

Lasko LM, Jakob CG, Edalji RP, Qiu W, Montgomery D, Digiammarino EL, Hansen TM, Risi RM, Frey R, Manaves V, Shaw B, Algire M, Hessler P, Lam LT, Uziel T, Faivre E, Ferguson D, Buchanan FG, Martin RL, Torrent M, Chiang GG, Karukurichi K, Langston JW, Weinert BT, Choudhary C, de Vries P, Van Drie JH, McElligott D, Kesicki E, Marmorstein R, Sun C, Cole PA, Rosenberg SH, Michaelides MR, Lai A, Bromberg KD.

Nature. 2017 Oct 5;550(7674):128-132. doi: 10.1038/nature24028. Epub 2017 Sep 27. Erratum in: Nature. 2018 May 16;:.

18.

Accurate Quantification of Site-specific Acetylation Stoichiometry Reveals the Impact of Sirtuin Deacetylase CobB on the E. coli Acetylome.

Weinert BT, Satpathy S, Hansen BK, Lyon D, Jensen LJ, Choudhary C.

Mol Cell Proteomics. 2017 May;16(5):759-769. doi: 10.1074/mcp.M117.067587. Epub 2017 Mar 2.

19.

Deubiquitylating enzyme USP9x regulates hippo pathway activity by controlling angiomotin protein turnover.

Thanh Nguyen H, Andrejeva D, Gupta R, Choudhary C, Hong X, Eichhorn PJ, Loya AC, Cohen SM.

Cell Discov. 2016 Mar 29;2:16001. doi: 10.1038/celldisc.2016.1. eCollection 2016.

20.

SPATA2 links CYLD to the TNF-α receptor signaling complex and modulates the receptor signaling outcomes.

Wagner SA, Satpathy S, Beli P, Choudhary C.

EMBO J. 2016 Sep 1;35(17):1868-84. doi: 10.15252/embj.201694300. Epub 2016 Jun 15.

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