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Items: 1 to 20 of 22

1.

Repeat polymorphisms in the Homo sapiens heme oxygenase-1 gene in diabetic and idiopathic gastroparesis.

Gibbons SJ, Grover M, Choi KM, Wadhwa A, Zubair A, Wilson LA, Wu Y, Abell TL, Hasler WL, Koch KL, McCallum RW, Nguyen LAB, Parkman HP, Sarosiek I, Snape WJ, Tonascia J, Hamilton FA, Pasricha PJ, Farrugia G.

PLoS One. 2017 Nov 21;12(11):e0187772. doi: 10.1371/journal.pone.0187772. eCollection 2017.

2.

Arterial stiffness induces remodeling phenotypes in pulmonary artery smooth muscle cells via YAP/TAZ-mediated repression of cyclooxygenase-2.

Dieffenbach PB, Haeger CM, Coronata AMF, Choi KM, Varelas X, Tschumperlin DJ, Fredenburgh LE.

Am J Physiol Lung Cell Mol Physiol. 2017 Sep 1;313(3):L628-L647. doi: 10.1152/ajplung.00173.2017. Epub 2017 Jun 22.

PMID:
28642262
3.

Zinc deficiency primes the lung for ventilator-induced injury.

Boudreault F, Pinilla-Vera M, Englert JA, Kho AT, Isabelle C, Arciniegas AJ, Barragan-Bradford D, Quintana C, Amador-Munoz D, Guan J, Choi KM; MICU Registry, Sholl L, Hurwitz S, Tschumperlin DJ, Baron RM.

JCI Insight. 2017 Jun 2;2(11). pii: 86507. doi: 10.1172/jci.insight.86507. [Epub ahead of print]

4.

Hyperglycemia Increases Interstitial Cells of Cajal via MAPK1 and MAPK3 Signaling to ETV1 and KIT, Leading to Rapid Gastric Emptying.

Hayashi Y, Toyomasu Y, Saravanaperumal SA, Bardsley MR, Smestad JA, Lorincz A, Eisenman ST, Cipriani G, Nelson Holte MH, Al Khazal FJ, Syed SA, Gajdos GB, Choi KM, Stoltz GJ, Miller KE, Kendrick ML, Rubin BP, Gibbons SJ, Bharucha AE, Linden DR, Maher LJ 3rd, Farrugia G, Ordog T.

Gastroenterology. 2017 Aug;153(2):521-535.e20. doi: 10.1053/j.gastro.2017.04.020. Epub 2017 Apr 21.

PMID:
28438610
5.

Caloric Restriction and Rapamycin Differentially Alter Energy Metabolism in Yeast.

Choi KM, Hong SJ, van Deursen JM, Kim S, Kim KH, Lee CK.

J Gerontol A Biol Sci Med Sci. 2017 Mar 8. doi: 10.1093/gerona/glx024. [Epub ahead of print]

PMID:
28329151
6.

TAZ activation drives fibroblast spheroid growth, expression of profibrotic paracrine signals, and context-dependent ECM gene expression.

Jorgenson AJ, Choi KM, Sicard D, Smith KM, Hiemer SE, Varelas X, Tschumperlin DJ.

Am J Physiol Cell Physiol. 2017 Mar 1;312(3):C277-C285. doi: 10.1152/ajpcell.00205.2016. Epub 2016 Nov 23.

PMID:
27881410
7.

Human airway organoid engineering as a step toward lung regeneration and disease modeling.

Tan Q, Choi KM, Sicard D, Tschumperlin DJ.

Biomaterials. 2017 Jan;113:118-132. doi: 10.1016/j.biomaterials.2016.10.046. Epub 2016 Oct 28.

PMID:
27815996
8.

Interleukin 10 Restores Gastric Emptying, Electrical Activity, and Interstitial Cells of Cajal Networks in Diabetic Mice.

Choi KM, Gibbons SJ, Sha L, Beyder A, Verhulst PJ, Cipriani G, Phillips JE, Bauer AJ, Ordog T, Camp JJ, Ge X, Bharucha AE, Linden DR, Szurszewski JH, Kashyap PC, Farrugia G.

Cell Mol Gastroenterol Hepatol. 2016 Apr 23;2(4):454-467. eCollection 2016 Jul.

9.

Effects of hemin on heme oxygenase-1, gastric emptying, and symptoms in diabetic gastroparesis.

Bharucha AE, Daley SL, Low PA, Gibbons SJ, Choi KM, Camilleri M, Saw JJ, Farrugia G, Zinsmeister AR.

Neurogastroenterol Motil. 2016 Nov;28(11):1731-1740. doi: 10.1111/nmo.12874. Epub 2016 Jun 9.

10.

Diabetic Csf1op/op mice lacking macrophages are protected against the development of delayed gastric emptying.

Cipriani G, Gibbons SJ, Verhulst PJ, Choi KM, Eisenman ST, Hein SS, Ordog T, Linden DR, Szurszewski JH, Farrugia G.

Cell Mol Gastroenterol Hepatol. 2016 Jan 1;2(1):40-47.

11.

Platelet-Derived Growth Factor Receptor-α Regulates Proliferation of Gastrointestinal Stromal Tumor Cells With Mutations in KIT by Stabilizing ETV1.

Hayashi Y, Bardsley MR, Toyomasu Y, Milosavljevic S, Gajdos GB, Choi KM, Reid-Lombardo KM, Kendrick ML, Bingener-Casey J, Tang CM, Sicklick JK, Gibbons SJ, Farrugia G, Taguchi T, Gupta A, Rubin BP, Fletcher JA, Ramachandran A, Ordog T.

Gastroenterology. 2015 Aug;149(2):420-32.e16. doi: 10.1053/j.gastro.2015.04.006. Epub 2015 Apr 9.

12.

Matrix stiffness-modulated proliferation and secretory function of the airway smooth muscle cells.

Shkumatov A, Thompson M, Choi KM, Sicard D, Baek K, Kim DH, Tschumperlin DJ, Prakash YS, Kong H.

Am J Physiol Lung Cell Mol Physiol. 2015 Jun 1;308(11):L1125-35. doi: 10.1152/ajplung.00154.2014. Epub 2015 Feb 27.

13.

Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis.

Liu F, Lagares D, Choi KM, Stopfer L, Marinković A, Vrbanac V, Probst CK, Hiemer SE, Sisson TH, Horowitz JC, Rosas IO, Fredenburgh LE, Feghali-Bostwick C, Varelas X, Tager AM, Tschumperlin DJ.

Am J Physiol Lung Cell Mol Physiol. 2015 Feb 15;308(4):L344-57. doi: 10.1152/ajplung.00300.2014. Epub 2014 Dec 12.

14.

Effects of aspirin & simvastatin and aspirin, simvastatin, & lipoic acid on heme oxygenase-1 in healthy human subjects.

Bharucha AE, Choi KM, Saw JJ, Gibbons SJ, Farrugia GF, Carlson DA, Zinsmeister AR.

Neurogastroenterol Motil. 2014 Oct;26(10):1437-42. doi: 10.1111/nmo.12404. Epub 2014 Jul 29.

15.

Assessment of gastric emptying in non-obese diabetic mice using a [13C]-octanoic acid breath test.

Creedon CT, Verhulst PJ, Choi KM, Mason JE, Linden DR, Szurszewski JH, Gibbons SJ, Farrugia G.

J Vis Exp. 2013 Mar 23;(73):e50301. doi: 10.3791/50301.

16.

Loss of Kitlow progenitors, reduced stem cell factor and high oxidative stress underlie gastric dysfunction in progeric mice.

Izbeki F, Asuzu DT, Lorincz A, Bardsley MR, Popko LN, Choi KM, Young DL, Hayashi Y, Linden DR, Kuro-o M, Farrugia G, Ordog T.

J Physiol. 2010 Aug 15;588(Pt 16):3101-17. doi: 10.1113/jphysiol.2010.191023. Epub 2010 Jun 25.

17.

Carbon monoxide reverses diabetic gastroparesis in NOD mice.

Kashyap PC, Choi KM, Dutta N, Linden DR, Szurszewski JH, Gibbons SJ, Farrugia G.

Am J Physiol Gastrointest Liver Physiol. 2010 Jun;298(6):G1013-9. doi: 10.1152/ajpgi.00069.2010. Epub 2010 Apr 8.

18.

CD206-positive M2 macrophages that express heme oxygenase-1 protect against diabetic gastroparesis in mice.

Choi KM, Kashyap PC, Dutta N, Stoltz GJ, Ordog T, Shea Donohue T, Bauer AJ, Linden DR, Szurszewski JH, Gibbons SJ, Farrugia G.

Gastroenterology. 2010 Jun;138(7):2399-409, 2409.e1. doi: 10.1053/j.gastro.2010.02.014. Epub 2010 Feb 20.

19.

First-in-human study demonstrating pharmacological activation of heme oxygenase-1 in humans.

Bharucha AE, Kulkarni A, Choi KM, Camilleri M, Lempke M, Brunn GJ, Gibbons SJ, Zinsmeister AR, Farrugia G.

Clin Pharmacol Ther. 2010 Feb;87(2):187-90. doi: 10.1038/clpt.2009.221. Epub 2009 Dec 2.

20.

Heme oxygenase-1 protects interstitial cells of Cajal from oxidative stress and reverses diabetic gastroparesis.

Choi KM, Gibbons SJ, Nguyen TV, Stoltz GJ, Lurken MS, Ordog T, Szurszewski JH, Farrugia G.

Gastroenterology. 2008 Dec;135(6):2055-64, 2064.e1-2. doi: 10.1053/j.gastro.2008.09.003. Epub 2008 Sep 11.

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