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CD36 Deficiency Inhibits Retinal Inflammation and Retinal Degeneration in Cx3cr1 Knockout Mice.

Lavalette S, Conart JB, Touhami S, Roubeix C, Houssier M, Augustin S, Raoul W, Combadière C, Febbraio M, Ong H, Chemtob S, Sahel JA, Delarasse C, Guillonneau X, Sennlaub F.

Front Immunol. 2020 Jan 8;10:3032. doi: 10.3389/fimmu.2019.03032. eCollection 2019.


Dynamic Chirality in the Mechanism of Action of Allosteric CD36 Modulators of Macrophage-Driven Inflammation.

Danelius E, Ohm RG, Ahsanullah, Mulumba M, Ong H, Chemtob S, Erdelyi M, Lubell WD.

J Med Chem. 2019 Dec 26;62(24):11071-11079. doi: 10.1021/acs.jmedchem.9b00918. Epub 2019 Dec 13.


Application of N-Dodecyl l-Peptide to Enhance Serum Stability while Maintaining Inhibitory Effects on Myometrial Contractions Ex Vivo.

Poupart J, Hou X, Chemtob S, Lubell WD.

Molecules. 2019 Nov 15;24(22). pii: E4141. doi: 10.3390/molecules24224141.


Propranolol Attenuates Proangiogenic Activity of Mononuclear Phagocytes: Implication in Choroidal Neovascularization.

Omri S, Tahiri H, Pierre WC, Desjarlais M, Lahaie I, Loiselle SE, Rezende F, Lodygensky G, Hebert TE, Ong H, Chemtob S.

Invest Ophthalmol Vis Sci. 2019 Nov 1;60(14):4632-4642. doi: 10.1167/iovs.18-25502.


Immunometabolic modulation of retinal inflammation by CD36 ligand.

Mellal K, Omri S, Mulumba M, Tahiri H, Fortin C, Dorion MF, Pham H, Garcia Ramos Y, Zhang J, Pundir S, Joyal JS, Bouchard JF, Sennlaub F, Febbraio M, Hardy P, Gravel SP, Marleau S, Lubell WD, Chemtob S, Ong H.

Sci Rep. 2019 Sep 9;9(1):12903. doi: 10.1038/s41598-019-49472-8.


The Inability of the Choroid to Revascularize in Oxygen-Induced Retinopathy Results from Increased p53/miR-Let-7b Activity.

Zhou TE, Zhu T, Rivera JC, Omri S, Tahiri H, Lahaie I, Rouget R, Wirth M, Nattel S, Lodygensky G, Ferbeyre G, Nezhady M, Desjarlais M, Hamel P, Chemtob S.

Am J Pathol. 2019 Nov;189(11):2340-2356. doi: 10.1016/j.ajpath.2019.07.009. Epub 2019 Aug 17.


Assessing therapeutic response non-invasively in a neonatal rat model of acute inflammatory white matter injury using high-field MRI.

Pierre WC, Akakpo L, Londono I, Pouliot P, Chemtob S, Lesage F, Lodygensky GA.

Brain Behav Immun. 2019 Oct;81:348-360. doi: 10.1016/j.bbi.2019.06.032. Epub 2019 Jun 24.


Müller Cell-Localized G-Protein-Coupled Receptor 81 (Hydroxycarboxylic Acid Receptor 1) Regulates Inner Retinal Vasculature via Norrin/Wnt Pathways.

Madaan A, Chaudhari P, Nadeau-Vallée M, Hamel D, Zhu T, Mitchell G, Samuels M, Pundir S, Dabouz R, Howe Cheng CW, Mohammad Nezhady MA, Joyal JS, Rivera JC, Chemtob S.

Am J Pathol. 2019 Sep;189(9):1878-1896. doi: 10.1016/j.ajpath.2019.05.016. Epub 2019 Jun 18.


MicroRNA expression profile in retina and choroid in oxygen-induced retinopathy model.

Desjarlais M, Rivera JC, Lahaie I, Cagnone G, Wirt M, Omri S, Chemtob S.

PLoS One. 2019 Jun 12;14(6):e0218282. doi: 10.1371/journal.pone.0218282. eCollection 2019.


Induced and spontaneous colitis mouse models reveal complex interactions between IL-10 and IL-12/IL-23 pathways.

Hurtubise R, Audiger C, Dominguez-Punaro MC, Chabot-Roy G, Chognard G, Raymond-Marchand L, Coderre L, Chemtob S, Michnick SW, Rioux JD, Lesage S.

Cytokine. 2019 Sep;121:154738. doi: 10.1016/j.cyto.2019.154738. Epub 2019 May 31.


Paired Utility of Aza-Amino Acyl Proline and Indolizidinone Amino Acid Residues for Peptide Mimicry: Conception of Prostaglandin F2α Receptor Allosteric Modulators That Delay Preterm Birth.

Mir FM, Atmuri NDP, Bourguet CB, Fores JR, Hou X, Chemtob S, Lubell WD.

J Med Chem. 2019 May 9;62(9):4500-4525. doi: 10.1021/acs.jmedchem.9b00056. Epub 2019 Apr 23.


Probing Anti-inflammatory Properties Independent of NF-κB Through Conformational Constraint of Peptide-Based Interleukin-1 Receptor Biased Ligands.

Geranurimi A, Cheng CWH, Quiniou C, Zhu T, Hou X, Rivera JC, St-Cyr DJ, Beauregard K, Bernard-Gauthier V, Chemtob S, Lubell WD.

Front Chem. 2019 Feb 13;7:23. doi: 10.3389/fchem.2019.00023. eCollection 2019.


Cooperative effects of sequential PGF2α and IL-1β on IL-6 and COX-2 expression in human myometrial cells†.

Leimert KB, Verstraeten BSE, Messer A, Nemati R, Blackadar K, Fang X, Robertson SA, Chemtob S, Olson DM.

Biol Reprod. 2019 May 1;100(5):1370-1385. doi: 10.1093/biolre/ioz029.


Multifactorial contributions to WINROP to enhance prediction of severe retinopathy of prematurity.

Wirth M, Desjarlais M, Chemtob S, Hascoët JM.

Acta Paediatr. 2019 Jun;108(6):1170. doi: 10.1111/apa.14736. Epub 2019 Feb 17. No abstract available.


Maternal and fetal intrauterine tissue crosstalk promotes proinflammatory amplification and uterine transition†.

Leimert KB, Messer A, Gray T, Fang X, Chemtob S, Olson DM.

Biol Reprod. 2019 Mar 1;100(3):783-797. doi: 10.1093/biolre/ioy232.


Evaluating the neuroprotective effect of 17β-estradiol in rodent models of oxidative retinopathies.

Chaychi S, Polosa A, Chemtob S, Lachapelle P.

Doc Ophthalmol. 2018 Dec;137(3):151-168. doi: 10.1007/s10633-018-9658-6. Epub 2018 Oct 27.


Azasulfurylpeptide Modulation of CD36-Mediated Inflammation Without Effect on Neovascularization.

Turcotte S, Mellal K, Chingle R, Mulumba M, Omri S, Dif-Yaiche L, Chemtob S, Ong H, Lubell WD.

Biomedicines. 2018 Oct 22;6(4). pii: E98. doi: 10.3390/biomedicines6040098.


Antitumor activity of cell-penetrant kinin B1 receptor antagonists in human triple-negative breast cancer cells.

Dubuc C, Savard M, Bovenzi V, Lessard A, Côté J, Neugebauer W, Geha S, Chemtob S, Gobeil F Jr.

J Cell Physiol. 2019 Mar;234(3):2851-2865. doi: 10.1002/jcp.27103. Epub 2018 Aug 21.


Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny.

Beaudry-Richard A, Nadeau-Vallée M, Prairie É, Maurice N, Heckel É, Nezhady M, Pundir S, Madaan A, Boudreault A, Hou X, Quiniou C, Sierra EM, Beaulac A, Lodygensky G, Robertson SA, Keelan J, Adams-Waldorf K, Olson DM, Rivera JC, Lubell WD, Joyal JS, Bouchard JF, Chemtob S.

Sci Rep. 2018 Aug 8;8(1):11875. doi: 10.1038/s41598-018-30087-4.


Receptors of intermediates of carbohydrate metabolism, GPR91 and GPR99, mediate axon growth.

Cherif H, Duhamel F, Cécyre B, Bouchard A, Quintal A, Chemtob S, Bouchard JF.

PLoS Biol. 2018 May 17;16(5):e2003619. doi: 10.1371/journal.pbio.2003619. eCollection 2018 May.

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