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Items: 1 to 20 of 253


Antitumor activity of cell-penetrant kinin B1 receptor antagonists in human triple-negative breast cancer cells.

Dubuc C, Savard M, Bovenzi V, Lessard A, Côté J, Neugebauer W, Geha S, Chemtob S, Gobeil F Jr.

J Cell Physiol. 2018 Aug 21. doi: 10.1002/jcp.27103. [Epub ahead of print]


Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny.

Beaudry-Richard A, Nadeau-Vallée M, Prairie É, Maurice N, Heckel É, Nezhady M, Pundir S, Madaan A, Boudreault A, Hou X, Quiniou C, Sierra EM, Beaulac A, Lodygensky G, Robertson SA, Keelan J, Adams-Waldorf K, Olson DM, Rivera JC, Lubell WD, Joyal JS, Bouchard JF, Chemtob S.

Sci Rep. 2018 Aug 8;8(1):11875. doi: 10.1038/s41598-018-30087-4.


Receptors of intermediates of carbohydrate metabolism, GPR91 and GPR99, mediate axon growth.

Cherif H, Duhamel F, Cécyre B, Bouchard A, Quintal A, Chemtob S, Bouchard JF.

PLoS Biol. 2018 May 17;16(5):e2003619. doi: 10.1371/journal.pbio.2003619. eCollection 2018 May.


Targeting intracellular B2 receptors using novel cell-penetrating antagonists to arrest growth and induce apoptosis in human triple-negative breast cancer.

Dubuc C, Savard M, Bovenzi V, Lessard A, Fortier A, Côté J, Neugebauer W, Rizzolio F, Geha S, Giordano A, Chemtob S, Gobeil F.

Oncotarget. 2018 Jan 5;9(11):9885-9906. doi: 10.18632/oncotarget.24009. eCollection 2018 Feb 9.


Ischemic Retinopathies: Oxidative Stress and Inflammation.

Rivera JC, Dabouz R, Noueihed B, Omri S, Tahiri H, Chemtob S.

Oxid Med Cell Longev. 2017;2017:3940241. doi: 10.1155/2017/3940241. Epub 2017 Dec 19. Review.


miR-126-5p promotes retinal endothelial cell survival through SetD5 regulation in neurons.

Villain G, Poissonnier L, Noueihed B, Bonfils G, Rivera JC, Chemtob S, Soncin F, Mattot V.

Development. 2018 Jan 8;145(1). pii: dev156232. doi: 10.1242/dev.156232.


Influences of Histidine-1 and Azaphenylalanine-4 on the Affinity, Anti-inflammatory, and Antiangiogenic Activities of Azapeptide Cluster of Differentiation 36 Receptor Modulators.

Chignen Possi K, Mulumba M, Omri S, Garcia-Ramos Y, Tahiri H, Chemtob S, Ong H, Lubell WD.

J Med Chem. 2017 Nov 22;60(22):9263-9274. doi: 10.1021/acs.jmedchem.7b01209. Epub 2017 Nov 1.


Tetrahydrobiopterin (BH4) deficiency is associated with augmented inflammation and microvascular degeneration in the retina.

Rivera JC, Noueihed B, Madaan A, Lahaie I, Pan J, Belik J, Chemtob S.

J Neuroinflammation. 2017 Sep 6;14(1):181. doi: 10.1186/s12974-017-0955-x.


Preterm Birth and Neonatal Injuries: Importance of Interleukin-1 and Potential of Interleukin-1 Receptor Antagonists.

Nadeau-Vallee M, Obari D, Beaudry-Richard A, Sierra EM, Beaulac A, Maurice N, Olson DM, Chemtob S.

Curr Pharm Des. 2017;23(40):6132-6141. doi: 10.2174/1381612823666170825145114.


Retinopathy of prematurity: inflammation, choroidal degeneration, and novel promising therapeutic strategies.

Rivera JC, Holm M, Austeng D, Morken TS, Zhou TE, Beaudry-Richard A, Sierra EM, Dammann O, Chemtob S.

J Neuroinflammation. 2017 Aug 22;14(1):165. doi: 10.1186/s12974-017-0943-1. Review.


Antenatal Suppression of IL-1 Protects against Inflammation-Induced Fetal Injury and Improves Neonatal and Developmental Outcomes in Mice.

Nadeau-Vallée M, Chin PY, Belarbi L, Brien MÈ, Pundir S, Berryer MH, Beaudry-Richard A, Madaan A, Sharkey DJ, Lupien-Meilleur A, Hou X, Quiniou C, Beaulac A, Boufaied I, Boudreault A, Carbonaro A, Doan ND, Joyal JS, Lubell WD, Olson DM, Robertson SA, Girard S, Chemtob S.

J Immunol. 2017 Mar 1;198(5):2047-2062. doi: 10.4049/jimmunol.1601600. Epub 2017 Feb 1.


Cone Genesis Tracing by the Chrnb4-EGFP Mouse Line: Evidences of Cellular Material Fusion after Cone Precursor Transplantation.

Decembrini S, Martin C, Sennlaub F, Chemtob S, Biel M, Samardzija M, Moulin A, Behar-Cohen F, Arsenijevic Y.

Mol Ther. 2017 Mar 1;25(3):634-653. doi: 10.1016/j.ymthe.2016.12.015. Epub 2017 Jan 28.


New insights into mechanisms of nuclear translocation of G-protein coupled receptors.

Bhosle VK, Rivera JC, Chemtob S.

Small GTPases. 2017 Jan 26:1-10. doi: 10.1080/21541248.2017.1282402. [Epub ahead of print]


Preventing Corneal Calcification Associated With Xylazine for Longitudinal Optical Coherence Tomography in Young Rodents.

Zhou TE, Sayah DN, Noueihed B, Mazzaferri J, Costantino S, Brunette I, Chemtob S.

Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):461-469. doi: 10.1167/iovs.16-20526.


Lymphocytic Microparticles Modulate Angiogenic Properties of Macrophages in Laser-induced Choroidal Neovascularization.

Tahiri H, Omri S, Yang C, Duhamel F, Samarani S, Ahmad A, Vezina M, Bussières M, Vaucher E, Sapieha P, Hickson G, Hammamji K, Lapointe R, Rodier F, Tremblay S, Royal I, Cailhier JF, Chemtob S, Hardy P.

Sci Rep. 2016 Nov 22;6:37391. doi: 10.1038/srep37391.


Sterile inflammation and pregnancy complications: a review.

Nadeau-Vallée M, Obari D, Palacios J, Brien MÈ, Duval C, Chemtob S, Girard S.

Reproduction. 2016 Dec;152(6):R277-R292. Epub 2016 Sep 27. Review.


Choroidal Involution Is Associated with a Progressive Degeneration of the Outer Retinal Function in a Model of Retinopathy of Prematurity: Early Role for IL-1β.

Zhou TE, Rivera JC, Bhosle VK, Lahaie I, Shao Z, Tahiri H, Zhu T, Polosa A, Dorfman A, Beaudry-Richard A, Costantino S, Lodygensky GA, Lachapelle P, Chemtob S.

Am J Pathol. 2016 Dec;186(12):3100-3116. doi: 10.1016/j.ajpath.2016.08.004. Epub 2016 Oct 18.


Erratum: Nuclear localization of platelet-activating factor receptor controls retinal neovascularization.

Bhosle VK, Rivera JC, Zhou TE, Omri S, Sanchez M, Hamel D, Zhu T, Rouget R, Rabea AA, Hou X, Lahaie I, Ribeiro-da-Silva A, Chemtob S.

Cell Discov. 2016 Sep 20;2:16034. doi: 10.1038/celldisc.2016.34. eCollection 2016.


Review of the mechanisms and therapeutic avenues for retinal and choroidal vascular dysfunctions in retinopathy of prematurity.

Rivera JC, Madaan A, Zhou TE, Chemtob S.

Acta Paediatr. 2016 Dec;105(12):1421-1433. doi: 10.1111/apa.13586. Epub 2016 Sep 28. Review.


Lactate produced during labor modulates uterine inflammation via GPR81 (HCA1).

Madaan A, Nadeau-Vallée M, Rivera JC, Obari D, Hou X, Sierra EM, Girard S, Olson DM, Chemtob S.

Am J Obstet Gynecol. 2017 Jan;216(1):60.e1-60.e17. doi: 10.1016/j.ajog.2016.09.072. Epub 2016 Sep 9.


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