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Items: 1 to 20 of 52


Formation of nanotubular TiO2 structures with varied surface characteristics for biomaterial applications.

Aguirre R, Echeverry-Rendón M, Quintero D, Castaño JG, Harmsen MC, Robledo S, Echeverría E F.

J Biomed Mater Res A. 2018 May;106(5):1341-1354. doi: 10.1002/jbm.a.36331. Epub 2018 Jan 31.


Lysine-Less Variants of Spinal Muscular Atrophy SMN and SMNΔ7 Proteins Are Degraded by the Proteasome Pathway.

Sánchez-Lanzas R, Castaño JG.

Int J Mol Sci. 2017 Dec 8;18(12). pii: E2667. doi: 10.3390/ijms18122667.


CCAAT/Enhancer binding protein β silencing mitigates glial activation and neurodegeneration in a rat model of Parkinson's disease.

Morales-Garcia JA, Gine E, Hernandez-Encinas E, Aguilar-Morante D, Sierra-Magro A, Sanz-SanCristobal M, Alonso-Gil S, Sanchez-Lanzas R, Castaño JG, Santos A, Perez-Castillo A.

Sci Rep. 2017 Oct 19;7(1):13526. doi: 10.1038/s41598-017-13269-4.


Modification of titanium alloys surface properties by plasma electrolytic oxidation (PEO) and influence on biological response.

Echeverry-Rendón M, Galvis O, Aguirre R, Robledo S, Castaño JG, Echeverría F.

J Mater Sci Mater Med. 2017 Sep 27;28(11):169. doi: 10.1007/s10856-017-5972-x.


Protein degradation in a LAMP-2-deficient B-lymphoblastoid cell line from a patient with Danon disease.

Sánchez-Lanzas R, Alvarez-Castelao B, Bermejo T, Ayuso T, Tuñón T, Castaño JG.

Biochim Biophys Acta. 2016 Aug;1862(8):1423-32. doi: 10.1016/j.bbadis.2016.04.014. Epub 2016 Apr 26.


α-Synuclein expression levels do not significantly affect proteasome function and expression in mice and stably transfected PC12 cell lines.

Martìn-Clemente B, Alvarez-Castelao B, Mayo I, Sierra AB, Díaz V, Milán M, Fariñas I, Gómez-Isla T, Ferrer I, Castaño JG.

J Biol Chem. 2016 Apr 22;291(17):8986. doi: 10.1074/jbc.A116.409028. No abstract available.


Osseointegration improvement by plasma electrolytic oxidation of modified titanium alloys surfaces.

Echeverry-Rendón M, Galvis O, Quintero Giraldo D, Pavón J, López-Lacomba JL, Jiménez-Piqué E, Anglada M, Robledo SM, Castaño JG, Echeverría F.

J Mater Sci Mater Med. 2015 Feb;26(2):72. doi: 10.1007/s10856-015-5408-4. Epub 2015 Jan 29.


Proteins directly interacting with mammalian 20S proteasomal subunits and ubiquitin-independent proteasomal degradation.

Sánchez-Lanzas R, Castaño JG.

Biomolecules. 2014 Dec 19;4(4):1140-54. doi: 10.3390/biom4041140. Review.


Epitope Mapping of Antibodies to Alpha-Synuclein in LRRK2 Mutation Carriers, Idiopathic Parkinson Disease Patients, and Healthy Controls.

Alvarez-Castelao B, Gorostidi A, Ruíz-Martínez J, López de Munain A, Castaño JG.

Front Aging Neurosci. 2014 Jul 15;6:169. doi: 10.3389/fnagi.2014.00169. eCollection 2014.


Mechanism of cleavage of alpha-synuclein by the 20S proteasome and modulation of its degradation by the RedOx state of the N-terminal methionines.

Alvarez-Castelao B, Goethals M, Vandekerckhove J, Castaño JG.

Biochim Biophys Acta. 2014 Feb;1843(2):352-65. doi: 10.1016/j.bbamcr.2013.11.018. Epub 2013 Dec 3.


The N-terminal region of Nurr1 (a.a 1-31) is essential for its efficient degradation by the ubiquitin proteasome pathway.

Alvarez-Castelao B, Losada F, Ahicart P, Castaño JG.

PLoS One. 2013;8(2):e55999. doi: 10.1371/journal.pone.0055999. Epub 2013 Feb 7.


A critical appraisal of quantitative studies of protein degradation in the framework of cellular proteostasis.

Alvarez-Castelao B, Ruiz-Rivas C, Castaño JG.

Biochem Res Int. 2012;2012:823597. doi: 10.1155/2012/823597. Epub 2012 Oct 21.


Reduced protein stability of human DJ-1/PARK7 L166P, linked to autosomal recessive Parkinson disease, is due to direct endoproteolytic cleavage by the proteasome.

Alvarez-Castelao B, Muñoz C, Sánchez I, Goethals M, Vandekerckhove J, Castaño JG.

Biochim Biophys Acta. 2012 Feb;1823(2):524-33. doi: 10.1016/j.bbamcr.2011.11.010. Epub 2011 Dec 8.


Synphilin-1 inhibits alpha-synuclein degradation by the proteasome.

Alvarez-Castelao B, Castaño JG.

Cell Mol Life Sci. 2011 Aug;68(15):2643-54. doi: 10.1007/s00018-010-0592-3. Epub 2010 Nov 20.


Cytomegalovirus promoter up-regulation is the major cause of increased protein levels of unstable reporter proteins after treatment of living cells with proteasome inhibitors.

Alvarez-Castelao B, Martín-Guerrero I, García-Orad A, Castaño JG.

J Biol Chem. 2009 Oct 9;284(41):28253-62. doi: 10.1074/jbc.M109.004101. Epub 2009 Aug 13. Retraction in: J Biol Chem. 2016 Apr 22;291(17):8985.


Parkin deficiency increases the resistance of midbrain neurons and glia to mild proteasome inhibition: the role of autophagy and glutathione homeostasis.

Casarejos MJ, Solano RM, Rodriguez-Navarro JA, Gómez A, Perucho J, Castaño JG, García de Yébenes J, Mena MA.

J Neurochem. 2009 Sep;110(5):1523-37. doi: 10.1111/j.1471-4159.2009.06248.x. Epub 2009 Jun 22.


Infection with Salmonella typhimurium has no effect on the composition and cleavage specificity of the 20S proteasome in human lymphoid cells.

Marcilla M, de Castro JA, Castaño JG, Alvarez I.

Immunology. 2007 Sep;122(1):131-9. Epub 2007 May 9.


Inhibition of 26S proteasome activity by huntingtin filaments but not inclusion bodies isolated from mouse and human brain.

Díaz-Hernández M, Valera AG, Morán MA, Gómez-Ramos P, Alvarez-Castelao B, Castaño JG, Hernández F, Lucas JJ.

J Neurochem. 2006 Sep;98(5):1585-96. Epub 2006 Jun 19.

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