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Items: 1 to 20 of 247

1.

Structures of neurexophilin-neurexin complexes reveal a regulatory mechanism of alternative splicing.

Wilson SC, White KI, Zhou Q, Pfuetzner RA, Choi UB, Südhof TC, Brunger AT.

EMBO J. 2019 Nov 15;38(22):e101603. doi: 10.15252/embj.2019101603. Epub 2019 Sep 30.

2.

The pre-synaptic fusion machinery.

Brunger AT, Choi UB, Lai Y, Leitz J, White KI, Zhou Q.

Curr Opin Struct Biol. 2019 Feb;54:179-188. doi: 10.1016/j.sbi.2019.03.007. Epub 2019 Apr 12. Review.

3.

Resolving indexing ambiguities in X-ray free-electron laser diffraction patterns.

Uervirojnangkoorn M, Lyubimov AY, Zhou Q, Weis WI, Brunger AT.

Acta Crystallogr D Struct Biol. 2019 Feb 1;75(Pt 2):234-241. doi: 10.1107/S2059798318013177. Epub 2019 Feb 6.

4.

Structural principles of SNARE complex recognition by the AAA+ protein NSF.

White KI, Zhao M, Choi UB, Pfuetzner RA, Brunger AT.

Elife. 2018 Sep 10;7. pii: e38888. doi: 10.7554/eLife.38888.

5.

NSF-mediated disassembly of on- and off-pathway SNARE complexes and inhibition by complexin.

Choi UB, Zhao M, White KI, Pfuetzner RA, Esquivies L, Zhou Q, Brunger AT.

Elife. 2018 Jul 9;7. pii: e36497. doi: 10.7554/eLife.36497.

6.

Molecular Mechanisms of Fast Neurotransmitter Release.

Brunger AT, Choi UB, Lai Y, Leitz J, Zhou Q.

Annu Rev Biophys. 2018 May 20;47:469-497. doi: 10.1146/annurev-biophys-070816-034117. Review.

7.

Ca2+-Triggered Synaptic Vesicle Fusion Initiated by Release of Inhibition.

Brunger AT, Leitz J, Zhou Q, Choi UB, Lai Y.

Trends Cell Biol. 2018 Aug;28(8):631-645. doi: 10.1016/j.tcb.2018.03.004. Epub 2018 Apr 26. Review.

8.

The Conformational Flexibility of the Acyltransferase from the Disorazole Polyketide Synthase Is Revealed by an X-ray Free-Electron Laser Using a Room-Temperature Sample Delivery Method for Serial Crystallography.

Mathews II, Allison K, Robbins T, Lyubimov AY, Uervirojnangkoorn M, Brunger AT, Khosla C, DeMirci H, McPhillips SE, Hollenbeck M, Soltis M, Cohen AE.

Biochemistry. 2017 Sep 12;56(36):4751-4756. doi: 10.1021/acs.biochem.7b00711. Epub 2017 Aug 31.

9.

The primed SNARE-complexin-synaptotagmin complex for neuronal exocytosis.

Zhou Q, Zhou P, Wang AL, Wu D, Zhao M, Südhof TC, Brunger AT.

Nature. 2017 Aug 24;548(7668):420-425. doi: 10.1038/nature23484. Epub 2017 Aug 16.

10.

Molecular Mechanisms of Synaptic Vesicle Priming by Munc13 and Munc18.

Lai Y, Choi UB, Leitz J, Rhee HJ, Lee C, Altas B, Zhao M, Pfuetzner RA, Wang AL, Brose N, Rhee J, Brunger AT.

Neuron. 2017 Aug 2;95(3):591-607.e10. doi: 10.1016/j.neuron.2017.07.004.

11.

Morphologies of synaptic protein membrane fusion interfaces.

Gipson P, Fukuda Y, Danev R, Lai Y, Chen DH, Baumeister W, Brunger AT.

Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):9110-9115. doi: 10.1073/pnas.1708492114. Epub 2017 Jul 24.

12.

Conformational change of syntaxin linker region induced by Munc13s initiates SNARE complex formation in synaptic exocytosis.

Wang S, Choi UB, Gong J, Yang X, Li Y, Wang AL, Yang X, Brunger AT, Ma C.

EMBO J. 2017 Mar 15;36(6):816-829. doi: 10.15252/embj.201695775. Epub 2017 Jan 30.

13.

Structure of photosystem II and substrate binding at room temperature.

Young ID, Ibrahim M, Chatterjee R, Gul S, Fuller F, Koroidov S, Brewster AS, Tran R, Alonso-Mori R, Kroll T, Michels-Clark T, Laksmono H, Sierra RG, Stan CA, Hussein R, Zhang M, Douthit L, Kubin M, de Lichtenberg C, Long Vo P, Nilsson H, Cheah MH, Shevela D, Saracini C, Bean MA, Seuffert I, Sokaras D, Weng TC, Pastor E, Weninger C, Fransson T, Lassalle L, Bräuer P, Aller P, Docker PT, Andi B, Orville AM, Glownia JM, Nelson S, Sikorski M, Zhu D, Hunter MS, Lane TJ, Aquila A, Koglin JE, Robinson J, Liang M, Boutet S, Lyubimov AY, Uervirojnangkoorn M, Moriarty NW, Liebschner D, Afonine PV, Waterman DG, Evans G, Wernet P, Dobbek H, Weis WI, Brunger AT, Zwart PH, Adams PD, Zouni A, Messinger J, Bergmann U, Sauter NK, Kern J, Yachandra VK, Yano J.

Nature. 2016 Dec 15;540(7633):453-457. doi: 10.1038/nature20161. Epub 2016 Nov 21.

14.

C-terminal domain of mammalian complexin-1 localizes to highly curved membranes.

Gong J, Lai Y, Li X, Wang M, Leitz J, Hu Y, Zhang Y, Choi UB, Cipriano D, Pfuetzner RA, Südhof TC, Yang X, Brunger AT, Diao J.

Proc Natl Acad Sci U S A. 2016 Nov 22;113(47):E7590-E7599. Epub 2016 Nov 7.

15.

Advances in X-ray free electron laser (XFEL) diffraction data processing applied to the crystal structure of the synaptotagmin-1 / SNARE complex.

Lyubimov AY, Uervirojnangkoorn M, Zeldin OB, Zhou Q, Zhao M, Brewster AS, Michels-Clark T, Holton JM, Sauter NK, Weis WI, Brunger AT.

Elife. 2016 Oct 12;5. pii: e18740. doi: 10.7554/eLife.18740.

16.

De novo phasing with X-ray laser reveals mosquito larvicide BinAB structure.

Colletier JP, Sawaya MR, Gingery M, Rodriguez JA, Cascio D, Brewster AS, Michels-Clark T, Hice RH, Coquelle N, Boutet S, Williams GJ, Messerschmidt M, DePonte DP, Sierra RG, Laksmono H, Koglin JE, Hunter MS, Park HW, Uervirojnangkoorn M, Bideshi DK, Brunger AT, Federici BA, Sauter NK, Eisenberg DS.

Nature. 2016 Nov 3;539(7627):43-47. doi: 10.1038/nature19825. Epub 2016 Sep 28.

17.

Expression of C1ql3 in Discrete Neuronal Populations Controls Efferent Synapse Numbers and Diverse Behaviors.

Martinelli DC, Chew KS, Rohlmann A, Lum MY, Ressl S, Hattar S, Brunger AT, Missler M, Südhof TC.

Neuron. 2016 Sep 7;91(5):1034-1051. doi: 10.1016/j.neuron.2016.07.002. Epub 2016 Jul 28.

18.

N-terminal domain of complexin independently activates calcium-triggered fusion.

Lai Y, Choi UB, Zhang Y, Zhao M, Pfuetzner RA, Wang AL, Diao J, Brunger AT.

Proc Natl Acad Sci U S A. 2016 Aug 9;113(32):E4698-707. doi: 10.1073/pnas.1604348113. Epub 2016 Jul 21.

19.

Phosphorylation of residues inside the SNARE complex suppresses secretory vesicle fusion.

Malmersjö S, Di Palma S, Diao J, Lai Y, Pfuetzner RA, Wang AL, McMahon MA, Hayer A, Porteus M, Bodenmiller B, Brunger AT, Meyer T.

EMBO J. 2016 Aug 15;35(16):1810-21. doi: 10.15252/embj.201694071. Epub 2016 Jul 11.

20.

IOTA: integration optimization, triage and analysis tool for the processing of XFEL diffraction images.

Lyubimov AY, Uervirojnangkoorn M, Zeldin OB, Brewster AS, Murray TD, Sauter NK, Berger JM, Weis WI, Brunger AT.

J Appl Crystallogr. 2016 May 11;49(Pt 3):1057-1064. eCollection 2016 Jun 1.

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