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Items: 1 to 20 of 167

1.

Laboratory Evolution of a Saccharomyces cerevisiae × S. eubayanus Hybrid Under Simulated Lager-Brewing Conditions.

Gorter de Vries AR, Voskamp MA, van Aalst ACA, Kristensen LH, Jansen L, van den Broek M, Salazar AN, Brouwers N, Abeel T, Pronk JT, Daran JG.

Front Genet. 2019 Mar 29;10:242. doi: 10.3389/fgene.2019.00242. eCollection 2019.

2.

A Single-Cell Atlas of the Tumor and Immune Ecosystem of Human Breast Cancer.

Wagner J, Rapsomaniki MA, Chevrier S, Anzeneder T, Langwieder C, Dykgers A, Rees M, Ramaswamy A, Muenst S, Soysal SD, Jacobs A, Windhager J, Silina K, van den Broek M, Dedes KJ, Rodríguez Martínez M, Weber WP, Bodenmiller B.

Cell. 2019 May 16;177(5):1330-1345.e18. doi: 10.1016/j.cell.2019.03.005. Epub 2019 Apr 11.

3.

Understanding the pathobiology in patent ductus arteriosus in prematurity-beyond prostaglandins and oxygen.

Hundscheid T, van den Broek M, van der Lee R, de Boode WP.

Pediatr Res. 2019 Apr 9. doi: 10.1038/s41390-019-0387-7. [Epub ahead of print]

PMID:
30965358
4.

In vivo recombination of Saccharomyces eubayanus maltose-transporter genes yields a chimeric transporter that enables maltotriose fermentation.

Brouwers N, Gorter de Vries AR, van den Broek M, Weening SM, Elink Schuurman TD, Kuijpers NGA, Pronk JT, Daran JG.

PLoS Genet. 2019 Apr 4;15(4):e1007853. doi: 10.1371/journal.pgen.1007853. eCollection 2019 Apr.

5.

The Genetic Makeup and Expression of the Glycolytic and Fermentative Pathways Are Highly Conserved Within the Saccharomyces Genus.

Boonekamp FJ, Dashko S, van den Broek M, Gehrmann T, Daran JM, Daran-Lapujade P.

Front Genet. 2018 Nov 16;9:504. doi: 10.3389/fgene.2018.00504. eCollection 2018.

6.

Allele-specific genome editing using CRISPR-Cas9 is associated with loss of heterozygosity in diploid yeast.

Gorter de Vries AR, Couwenberg LGF, van den Broek M, de la Torre Cortés P, Ter Horst J, Pronk JT, Daran JG.

Nucleic Acids Res. 2018 Dec 5. doi: 10.1093/nar/gky1216. [Epub ahead of print]

7.

Graft-versus-host disease, but not graft-versus-leukemia immunity, is mediated by GM-CSF-licensed myeloid cells.

Tugues S, Amorim A, Spath S, Martin-Blondel G, Schreiner B, De Feo D, Lutz M, Guscetti F, Apostolova P, Haftmann C, Hasselblatt P, Núñez NG, Hottiger MO, van den Broek M, Manz MG, Zeiser R, Becher B.

Sci Transl Med. 2018 Nov 28;10(469). pii: eaat8410. doi: 10.1126/scitranslmed.aat8410.

PMID:
30487251
8.

Prevalence and pathophysiology of early dumping in patients after primary Roux-en-Y gastric bypass during a mixed-meal tolerance test.

Wijma RB, Emous M, van den Broek M, Laskewitz A, Kobold ACM, van Beek AP.

Surg Obes Relat Dis. 2019 Jan;15(1):73-81. doi: 10.1016/j.soard.2018.10.004. Epub 2018 Oct 12.

PMID:
30446401
9.

A toolkit for rapid CRISPR-SpCas9 assisted construction of hexose-transport-deficient Saccharomyces cerevisiae strains.

Wijsman M, Swiat MA, Marques WL, Hettinga JK, van den Broek M, Torre Cortés P, Mans R, Pronk JT, Daran JM, Daran-Lapujade P.

FEMS Yeast Res. 2019 Jan 1;19(1). doi: 10.1093/femsyr/foy107.

10.

Laboratory evolution and physiological analysis of Saccharomyces cerevisiae strains dependent on sucrose uptake via the Phaseolus vulgaris Suf1 transporter.

Marques WL, van der Woude LN, Luttik MAH, van den Broek M, Nijenhuis JM, Pronk JT, van Maris AJA, Mans R, Gombert AK.

Yeast. 2018 Dec;35(12):639-652. doi: 10.1002/yea.3357. Epub 2018 Oct 15.

PMID:
30221387
11.

Gemcitabine Synergizes with Immune Checkpoint Inhibitors and Overcomes Resistance in a Preclinical Model and Mesothelioma Patients.

Tallón de Lara P, Cecconi V, Hiltbrunner S, Yagita H, Friess M, Bode B, Opitz I, Vrugt B, Weder W, Stolzmann P, Felley-Bosco E, Stahel RA, Tischler V, Britschgi C, Soldini D, van den Broek M, Curioni-Fontecedro A.

Clin Cancer Res. 2018 Dec 15;24(24):6345-6354. doi: 10.1158/1078-0432.CCR-18-1231. Epub 2018 Aug 28.

PMID:
30154226
12.

Structural, Physiological and Regulatory Analysis of Maltose Transporter Genes in Saccharomyces eubayanus CBS 12357T.

Brickwedde A, Brouwers N, van den Broek M, Gallego Murillo JS, Fraiture JL, Pronk JT, Daran JG.

Front Microbiol. 2018 Aug 10;9:1786. doi: 10.3389/fmicb.2018.01786. eCollection 2018.

13.

A Quantitative Pathology Approach to Analyze the Development of Human Cancer-Associated Tertiary Lymphoid Structures.

Siliņa K, Burkhardt C, Casanova R, Solterman A, van den Broek M.

Methods Mol Biol. 2018;1845:71-86. doi: 10.1007/978-1-4939-8709-2_5.

PMID:
30141008
14.

Selection of Pof-Saccharomyces eubayanus Variants for the Construction of S. cerevisiae × S. eubayanus Hybrids With Reduced 4-Vinyl Guaiacol Formation.

Diderich JA, Weening SM, van den Broek M, Pronk JT, Daran JG.

Front Microbiol. 2018 Jul 27;9:1640. doi: 10.3389/fmicb.2018.01640. eCollection 2018.

15.

Good and Bad Sides of Self-Compassion: A Face Validity Check of the Self-Compassion Scale and an Investigation of its Relations to Coping and Emotional Symptoms in Non-Clinical Adolescents.

Muris P, van den Broek M, Otgaar H, Oudenhoven I, Lennartz J.

J Child Fam Stud. 2018;27(8):2411-2421. doi: 10.1007/s10826-018-1099-z. Epub 2018 May 4.

16.

A local uPAR-plasmin-TGFβ1 positive feedback loop in a qualitative computational model of angiogenic sprouting explains the in vitro effect of fibrinogen variants.

Boas SEM, Carvalho J, van den Broek M, Weijers EM, Goumans MJ, Koolwijk P, Merks RMH.

PLoS Comput Biol. 2018 Jul 6;14(7):e1006239. doi: 10.1371/journal.pcbi.1006239. eCollection 2018 Jul.

17.

Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation.

Arnold IC, Artola-Borán M, Tallón de Lara P, Kyburz A, Taube C, Ottemann K, van den Broek M, Yousefi S, Simon HU, Müller A.

J Exp Med. 2018 Aug 6;215(8):2055-2072. doi: 10.1084/jem.20172049. Epub 2018 Jul 3.

18.

Satiety and gastrointestinal hormones during a Mixed Meal Tolerance Test after gastric bypass surgery: association with plasma amino acid concentrations.

van den Broek M, de Heide LJM, Emous M, Wijma RB, Veeger NJGM, Wolthuis A, Laskewitz AJ, Heiner-Fokkema MR, Muller Kobold AC, Wolffenbuttel BHR, van Beek AP.

Surg Obes Relat Dis. 2018 Aug;14(8):1106-1117. doi: 10.1016/j.soard.2018.05.010. Epub 2018 May 21.

PMID:
29937240
19.

CSF1R-dependent myeloid cells are required for NK‑mediated control of metastasis.

Beffinger M, Tallón de Lara P, Tugues S, Vermeer M, Montagnolo Y, Ohs I, Cecconi V, Lucchiari G, Gagliardi A, Misljencevic N, Sutton J, Spörri R, Becher B, Gupta A, van den Broek M.

JCI Insight. 2018 May 17;3(10). pii: 97792. doi: 10.1172/jci.insight.97792. eCollection 2018 May 17.

20.

WNT ligands control initiation and progression of human papillomavirus-driven squamous cell carcinoma.

Zimmerli D, Cecconi V, Valenta T, Hausmann G, Cantù C, Restivo G, Hafner J, Basler K, van den Broek M.

Oncogene. 2018 Jul;37(27):3753-3762. doi: 10.1038/s41388-018-0244-x. Epub 2018 Apr 17.

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