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Items: 1 to 20 of 68


Role of TNF-TNF Receptor 2 Signal in Regulatory T Cells and Its Therapeutic Implications.

Yang S, Wang J, Brand DD, Zheng SG.

Front Immunol. 2018 Apr 19;9:784. doi: 10.3389/fimmu.2018.00784. eCollection 2018. Review.


The role of Syk in peripheral T cells.

Park JE, Majumdar S, Brand DD, Rosloniec EF, Yi AK, Stuart JM, Kang AH, Myers LK.

Clin Immunol. 2018 Jul;192:50-57. doi: 10.1016/j.clim.2018.04.007. Epub 2018 Apr 16.


mPGES1-Dependent Prostaglandin E2 (PGE2) Controls Antigen-Specific Th17 and Th1 Responses by Regulating T Autocrine and Paracrine PGE2 Production.

Maseda D, Johnson EM, Nyhoff LE, Baron B, Kojima F, Wilhelm AJ, Ward MR, Woodward JG, Brand DD, Crofford LJ.

J Immunol. 2018 Jan 15;200(2):725-736. doi: 10.4049/jimmunol.1601808. Epub 2017 Dec 13.


In Vivo Attenuation of Antibody-Mediated Acute Renal Allograft Rejection by Ex Vivo TGF-β-Induced CD4+Foxp3+ Regulatory T Cells.

Liao T, Xue Y, Zhao D, Li S, Liu M, Chen J, Brand DD, Zheng H, Zhang Y, Zheng SG, Sun Q.

Front Immunol. 2017 Oct 16;8:1334. doi: 10.3389/fimmu.2017.01334. eCollection 2017.


The Role of Leukocyte-Associated Ig-like Receptor-1 in Suppressing Collagen-Induced Arthritis.

Kim S, Easterling ER, Price LC, Smith SL, Coligan JE, Park JE, Brand DD, Rosloniec EF, Stuart JM, Kang AH, Myers LK.

J Immunol. 2017 Oct 15;199(8):2692-2700. doi: 10.4049/jimmunol.1700271. Epub 2017 Sep 8.


Monomeric, porous type II collagen scaffolds promote chondrogenic differentiation of human bone marrow mesenchymal stem cells in vitro.

Tamaddon M, Burrows M, Ferreira SA, Dazzi F, Apperley JF, Bradshaw A, Brand DD, Czernuszka J, Gentleman E.

Sci Rep. 2017 Mar 3;7:43519. doi: 10.1038/srep43519.


Characterization of the Syk-Dependent T Cell Signaling Response to an Altered Peptide.

Park JE, Rotondo JA, Cullins DL, Brand DD, Yi AK, Stuart JM, Kang AH, Myers LK.

J Immunol. 2016 Dec 15;197(12):4569-4575. Epub 2016 Nov 11.


Bone loss and aggravated autoimmune arthritis in HLA-DRβ1-bearing humanized mice following oral challenge with Porphyromonas gingivalis.

Sandal I, Karydis A, Luo J, Prislovsky A, Whittington KB, Rosloniec EF, Dong C, Novack DV, Mydel P, Zheng SG, Radic MZ, Brand DD.

Arthritis Res Ther. 2016 Oct 26;18(1):249.


Cytochrome P450 1B1 Contributes to the Development of Angiotensin II-Induced Aortic Aneurysm in Male Apoe(-/-) Mice.

Thirunavukkarasu S, Khan NS, Song CY, Ghafoor HU, Brand DD, Gonzalez FJ, Malik KU.

Am J Pathol. 2016 Aug;186(8):2204-2219. doi: 10.1016/j.ajpath.2016.04.005. Epub 2016 Jun 11.


In Vivo Dual Fluorescence Imaging to Detect Joint Destruction.

Cho H, Bhatti FU, Lee S, Brand DD, Yi AK, Hasty KA.

Artif Organs. 2016 Oct;40(10):1009-1013. doi: 10.1111/aor.12685. Epub 2016 May 16.


6β-Hydroxytestosterone, a Cytochrome P450 1B1-Testosterone-Metabolite, Mediates Angiotensin II-Induced Renal Dysfunction in Male Mice.

Pingili AK, Thirunavukkarasu S, Kara M, Brand DD, Katsurada A, Majid DS, Navar LG, Gonzalez FJ, Malik KU.

Hypertension. 2016 May;67(5):916-26. doi: 10.1161/HYPERTENSIONAHA.115.06936. Epub 2016 Feb 29.


The CII-specific autoimmune T-cell response develops in the presence of FTY720 but is regulated by enhanced Treg cells that inhibit the development of autoimmune arthritis.

Miller DC, Whittington KB, Brand DD, Hasty KA, Rosloniec EF.

Arthritis Res Ther. 2016 Jan 12;18:8. doi: 10.1186/s13075-015-0909-6.


Peptide ligand structure and I-Aq binding avidity influence T cell signaling pathway utilization.

Myers LK, Cullins DL, Park JE, Yi AK, Brand DD, Rosloniec EF, Stuart JM, Kang AH.

Clin Immunol. 2015 Oct;160(2):188-97. doi: 10.1016/j.clim.2015.05.002. Epub 2015 May 14.


Genomic locus on chromosome 1 regulates susceptibility to spontaneous arthritis in mice deficiency of IL-1RA.

Deng N, Jiao Y, Cao Y, Liu X, Ma Y, Hasty KA, Brand DD, Stuart JM, Gu W.

BMC Immunol. 2014 Dec 9;15:57. doi: 10.1186/s12865-014-0057-9.


Critical role of all-trans retinoic acid in stabilizing human natural regulatory T cells under inflammatory conditions.

Lu L, Lan Q, Li Z, Zhou X, Gu J, Li Q, Wang J, Chen M, Liu Y, Shen Y, Brand DD, Ryffel B, Horwitz DA, Quismorio FP, Liu Z, Li B, Olsen NJ, Zheng SG.

Proc Natl Acad Sci U S A. 2014 Aug 19;111(33):E3432-40. doi: 10.1073/pnas.1408780111. Epub 2014 Aug 6.


Characterization of T cell phenotype and function in a double transgenic (collagen-specific TCR/HLA-DR1) humanized model of arthritis.

Tang B, Kim S, Hammond S, Cullins DL, Brand DD, Rosloniec EF, Stuart JM, Postlethwaite AE, Kang AH, Myers LK.

Arthritis Res Ther. 2014 Jan 10;16(1):R7. doi: 10.1186/ar4433.


Engineered regulatory T cells coexpressing MHC class II:peptide complexes are efficient inhibitors of autoimmune T cell function and prevent the development of autoimmune arthritis.

Qian Z, Latham KA, Whittington KB, Miller DC, Brand DD, Rosloniec EF.

J Immunol. 2013 Jun 1;190(11):5382-91. doi: 10.4049/jimmunol.1300024. Epub 2013 Apr 29.


Characterisation of freeze-dried type II collagen and chondroitin sulfate scaffolds.

Tamaddon M, Walton RS, Brand DD, Czernuszka JT.

J Mater Sci Mater Med. 2013 May;24(5):1153-65. doi: 10.1007/s10856-013-4882-9. Epub 2013 Feb 8.


Comprehensive mass spectrometric mapping of the hydroxylated amino acid residues of the α1(V) collagen chain.

Yang C, Park AC, Davis NA, Russell JD, Kim B, Brand DD, Lawrence MJ, Ge Y, Westphall MS, Coon JJ, Greenspan DS.

J Biol Chem. 2012 Nov 23;287(48):40598-610. doi: 10.1074/jbc.M112.406850. Epub 2012 Oct 11.


Characterization of inhibitory T cells induced by an analog of type II collagen in an HLA-DR1 humanized mouse model of autoimmune arthritis.

Kimata M, Cullins DL, Brown ML, Brand DD, Rosloniec EF, Myers LK, Stuart JM, Kang AH.

Arthritis Res Ther. 2012 May 8;14(3):R107. doi: 10.1186/ar3832.

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