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Items: 1 to 20 of 1170

1.

KLOTHO heterozygosity attenuates APOE4-related amyloid burden in preclinical AD.

Erickson CM, Schultz SA, Oh JM, Darst BF, Ma Y, Norton D, Betthauser T, Gallagher CL, Carlsson CM, Bendlin BB, Asthana S, Hermann BP, Sager MA, Blennow K, Zetterberg H, Engelman CD, Christian BT, Johnson SC, Dubal DB, Okonkwo OC.

Neurology. 2019 Mar 13. pii: 10.1212/WNL.0000000000007323. doi: 10.1212/WNL.0000000000007323. [Epub ahead of print]

PMID:
30867273
2.

Development of parallel reaction monitoring assays for cerebrospinal fluid proteins associated with Alzheimer's disease.

Andersson A, Remnestål J, Nellgård B, Vunk H, Kotol D, Edfors F, Uhlén M, Schwenk JM, Ilag LL, Zetterberg H, Blennow K, Månberg A, Nilsson P, Fredolini C.

Clin Chim Acta. 2019 Mar 8. pii: S0009-8981(19)30348-1. doi: 10.1016/j.cca.2019.03.243. [Epub ahead of print]

3.

Cerebrospinal fluid biomarkers of neurodegeneration, synaptic integrity, and astroglial activation across the clinical Alzheimer's disease spectrum.

Bos I, Vos S, Verhey F, Scheltens P, Teunissen C, Engelborghs S, Sleegers K, Frisoni G, Blin O, Richardson JC, Bordet R, Tsolaki M, Popp J, Peyratout G, Martinez-Lage P, Tainta M, Lleó A, Johannsen P, Freund-Levi Y, Frölich L, Vandenberghe R, Westwood S, Dobricic V, Barkhof F, Legido-Quigley C, Bertram L, Lovestone S, Streffer J, Andreasson U, Blennow K, Zetterberg H, Visser PJ.

Alzheimers Dement. 2019 Mar 7. pii: S1552-5260(19)30018-4. doi: 10.1016/j.jalz.2019.01.004. [Epub ahead of print]

PMID:
30853464
4.

Serum Neurofilament Light is Elevated Differentially in Older Adults with Uncomplicated Mild Traumatic Brain Injuries.

Iverson GL, Reddi PJ, Posti JP, Kotilainen AK, Tenovuo O, Öhman J, Zetterberg H, Blennow K, Luoto TM.

J Neurotrauma. 2019 Mar 7. doi: 10.1089/neu.2018.6341. [Epub ahead of print]

PMID:
30843469
5.

Human cerebrospinal fluid 6E10-immunoreactive protein species contain amyloid precursor protein fragments.

Grant MKO, Handoko M, Rozga M, Brinkmalm G, Portelius E, Blennow K, Ashe KH, Zahs KR, Liu P.

PLoS One. 2019 Feb 28;14(2):e0212815. doi: 10.1371/journal.pone.0212815. eCollection 2019.

6.

Pyroglutamation of amyloid-βx-42 (Aβx-42) followed by Aβ1-40 deposition underlies plaque polymorphism in progressing Alzheimer's disease pathology.

Michno W, Nyström S, Wehrli P, Lashley T, Brinkmalm G, Guerard L, Syvänen S, Sehlin D, Kaya I, Brinet D, Nilsson KPR, Hammarström P, Blennow K, Zetterberg H, Hanrieder J.

J Biol Chem. 2019 Feb 27. pii: jbc.RA118.006604. doi: 10.1074/jbc.RA118.006604. [Epub ahead of print]

7.

A distinct brain beta amyloid signature in cerebral amyloid angiopathy compared to Alzheimer's disease.

Gkanatsiou E, Portelius E, Toomey CE, Blennow K, Zetterberg H, Lashley T, Brinkmalm G.

Neurosci Lett. 2019 Feb 23;701:125-131. doi: 10.1016/j.neulet.2019.02.033. [Epub ahead of print]

PMID:
30807796
8.

Synaptic vesicle protein 2A as a potential biomarker in synaptopathies.

Heurling K, Ashton NJ, Leuzy A, Zimmer ER, Blennow K, Zetterberg H, Eriksson J, Lubberink M, Schöll M.

Mol Cell Neurosci. 2019 Feb 20. pii: S1044-7431(18)30297-5. doi: 10.1016/j.mcn.2019.02.001. [Epub ahead of print] Review.

9.

Increased Secondary Nucleation Underlies Accelerated Aggregation of the Four-Residue N-Terminally Truncated Aβ42 Species Aβ5-42.

Weiffert T, Meisl G, Flagmeier P, De S, Dunning CJR, Frohm B, Zetterberg H, Blennow K, Portelius E, Klenerman D, Dobson CM, Knowles TPJ, Linse S.

ACS Chem Neurosci. 2019 Mar 8. doi: 10.1021/acschemneuro.8b00676. [Epub ahead of print]

PMID:
30793584
10.

Association of IL1RAP-related genetic variation with cerebrospinal fluid concentration of Alzheimer-associated tau protein.

Zettergren A, Höglund K, Kern S, Thorvaldsson V, Johan Skoog M, Hansson O, Andreasen N, Bogdanovic N, Blennow K, Skoog I, Zetterberg H.

Sci Rep. 2019 Feb 21;9(1):2460. doi: 10.1038/s41598-018-36650-3.

11.

Sleep oscillation-specific associations with Alzheimer's disease CSF biomarkers: novel roles for sleep spindles and tau.

Kam K, Parekh A, Sharma RA, Andrade A, Lewin M, Castillo B, Bubu OM, Chua NJ, Miller MD, Mullins AE, Glodzik L, Mosconi L, Gosselin N, Prathamesh K, Chen Z, Blennow K, Zetterberg H, Bagchi N, Cavedoni B, Rapoport DM, Ayappa I, de Leon MJ, Petkova E, Varga AW, Osorio RS.

Mol Neurodegener. 2019 Feb 21;14(1):10. doi: 10.1186/s13024-019-0309-5.

12.

Longitudinal measurement of serum neurofilament light in presymptomatic familial Alzheimer's disease.

Weston PSJ, Poole T, O'Connor A, Heslegrave A, Ryan NS, Liang Y, Druyeh R, Mead S, Blennow K, Schott JM, Frost C, Zetterberg H, Fox NC.

Alzheimers Res Ther. 2019 Feb 20;11(1):19. doi: 10.1186/s13195-019-0472-5.

13.

NFL blood levels are moderated by subconcussive impacts in a cohort of college football players.

Rubin LH, Tierney R, Kawata K, Wesley L, Lee JH, Blennow K, Zetterberg H, Langford D.

Brain Inj. 2019;33(4):456-462. doi: 10.1080/02699052.2019.1565895. Epub 2019 Jan 11.

PMID:
30776989
14.

A plasma protein classifier for predicting amyloid burden for preclinical Alzheimer's disease.

Ashton NJ, Nevado-Holgado AJ, Barber IS, Lynham S, Gupta V, Chatterjee P, Goozee K, Hone E, Pedrini S, Blennow K, Schöll M, Zetterberg H, Ellis KA, Bush AI, Rowe CC, Villemagne VL, Ames D, Masters CL, Aarsland D, Powell J, Lovestone S, Martins R, Hye A.

Sci Adv. 2019 Feb 6;5(2):eaau7220. doi: 10.1126/sciadv.aau7220. eCollection 2019 Feb.

15.

Cerebrospinal fluid biomarkers for understanding multiple aspects of Alzheimer's disease pathogenesis.

Dhiman K, Blennow K, Zetterberg H, Martins RN, Gupta VB.

Cell Mol Life Sci. 2019 Feb 15. doi: 10.1007/s00018-019-03040-5. [Epub ahead of print] Review.

PMID:
30770953
16.

Correlation of blood biomarkers and biomarker panels with traumatic findings on computed tomography after traumatic brain injury.

Posti JP, Takala RS, Lagerstedt L, Dickens AM, Hossain I, Mohammadian M, Ala-Seppälä HM, Frantzén J, Van Gils M, Hutchinson PJ, Katila AJ, Maanpää HR, Menon D, Newcombe V, Tallus J, Hrusovsky K, Wilson D, Gill J, Sanchez JC, Tenovuo O, Zetterberg H, Blennow K.

J Neurotrauma. 2019 Feb 14. doi: 10.1089/neu.2018.6254. [Epub ahead of print]

PMID:
30760178
17.

Comparison of plasma and cerebrospinal fluid neurofilament light in a multiple sclerosis trial.

de Flon P, Laurell K, Sundström P, Blennow K, Söderström L, Zetterberg H, Gunnarsson M, Svenningsson A.

Acta Neurol Scand. 2019 Feb 11. doi: 10.1111/ane.13078. [Epub ahead of print]

PMID:
30740668
18.

Neurogranin as a potential synaptic marker in the cerebrospinal fluid of patients with a first episode psychosis.

Santillo AF, Lundgren S, Xu C, Orhan F, Fatouros-Bergman H, Blennow K, Zetterberg H, Portelius E; Karolinska Schizophrenia Project (KaSP) Consortium, Cervenka S, Jönsson EG, Erhardt S, Engberg G.

Schizophr Res. 2019 Feb 4. pii: S0920-9964(19)30010-6. doi: 10.1016/j.schres.2019.01.010. [Epub ahead of print] No abstract available.

PMID:
30733168
19.

Peptidomic analysis of cartilage and subchondral bone in OA patients.

Gatenholm B, Gobom J, Skillbäck T, Blennow K, Zetterberg H, Brittberg M.

Eur J Clin Invest. 2019 Feb 6:e13082. doi: 10.1111/eci.13082. [Epub ahead of print]

PMID:
30725487
20.

Cerebrospinal fluid levels of glial marker YKL-40 strongly associated with axonal injury in HIV infection.

Hermansson L, Yilmaz A, Axelsson M, Blennow K, Fuchs D, Hagberg L, Lycke J, Zetterberg H, Gisslén M.

J Neuroinflammation. 2019 Jan 24;16(1):16. doi: 10.1186/s12974-019-1404-9.

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