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Long-Acting and Selective Oxytocin Peptide Analogs Show Antidiabetic and Antiobesity Effects in Male Mice.

Snider B, Geiser A, Yu XP, Beebe EC, Willency JA, Qing K, Guo L, Lu J, Wang X, Yang Q, Efanov A, Adams AC, Coskun T, Emmerson PJ, Alsina-Fernandez J, Ai M.

J Endocr Soc. 2019 May 16;3(7):1423-1444. doi: 10.1210/js.2019-00004. eCollection 2019 Jul 1.


Vagal nerve stimulation for intractable hiccups is not a panacea: a case report and review of the literature.

Grewal SS, Adams AC, Van Gompel JJ.

Int J Neurosci. 2018 Dec;128(12):1114-1117. doi: 10.1080/00207454.2018.1486307. Epub 2018 Jul 3. Review.


Eccentric exercise increases circulating fibroblast activation protein α but not bioactive fibroblast growth factor 21 in healthy humans.

Parmar B, Lewis JE, Samms RJ, Ebling FJP, Cheng CC, Adams AC, Mallinson J, Cooper S, Taylor T, Ghasemi R, Stephens FB, Tsintzas K.

Exp Physiol. 2018 Jun;103(6):876-883. doi: 10.1113/EP086669.


Cholic Acid Supplementation of a High-Fat Obesogenic Diet Suppresses Hepatic Triacylglycerol Accumulation in Mice via a Fibroblast Growth Factor 21-Dependent Mechanism.

Ippagunta SM, Kharitonenkov A, Adams AC, Hillgartner FB.

J Nutr. 2018 Apr 1;148(4):510-517. doi: 10.1093/jn/nxy022.


CMPF, a Metabolite Formed Upon Prescription Omega-3-Acid Ethyl Ester Supplementation, Prevents and Reverses Steatosis.

Prentice KJ, Wendell SG, Liu Y, Eversley JA, Salvatore SR, Mohan H, Brandt SL, Adams AC, Serena Wang X, Wei D, FitzGerald GA, Durham TB, Hammond CD, Sloop KW, Skarke C, Schopfer FJ, Wheeler MB.

EBioMedicine. 2018 Jan;27:200-213. doi: 10.1016/j.ebiom.2017.12.019. Epub 2017 Dec 19.


Acute loss of adipose tissue-derived adiponectin triggers immediate metabolic deterioration in mice.

Xia JY, Sun K, Hepler C, Ghaben AL, Gupta RK, An YA, Holland WL, Morley TS, Adams AC, Gordillo R, Kusminski CM, Scherer PE.

Diabetologia. 2018 Apr;61(4):932-941. doi: 10.1007/s00125-017-4516-8. Epub 2017 Dec 9.


Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury.

Desai BN, Singhal G, Watanabe M, Stevanovic D, Lundasen T, Fisher FM, Mather ML, Vardeh HG, Douris N, Adams AC, Nasser IA, FitzGerald GA, Flier JS, Skarke C, Maratos-Flier E.

Mol Metab. 2017 Nov;6(11):1395-1406. doi: 10.1016/j.molmet.2017.08.004. Epub 2017 Aug 19.


Discrepancies between recruitment status and actual trial status: a cross-sectional analysis.

Jones CW, Safferman MR, Adams AC, Platts-Mills TF.

BMJ Open. 2017 Oct 11;7(10):e017719. doi: 10.1136/bmjopen-2017-017719.


Antibody-Mediated Targeting of the FGFR1c Isoform Increases Glucose Uptake in White and Brown Adipose Tissue in Male Mice.

Lewis JE, Samms RJ, Cooper S, Luckett JC, Perkins AC, Dunbar JD, Smith DP, Emmerson PJ, Adams AC, Ebling FJP, Tsintzas K.

Endocrinology. 2017 Oct 1;158(10):3090-3096. doi: 10.1210/en.2017-00591.


FGF21 Is an Insulin-Dependent Postprandial Hormone in Adult Humans.

Samms RJ, Lewis JE, Norton L, Stephens FB, Gaffney CJ, Butterfield T, Smith DP, Cheng CC, Perfield JW 2nd, Adams AC, Ebling FJP, Tsintzas K.

J Clin Endocrinol Metab. 2017 Oct 1;102(10):3806-3813. doi: 10.1210/jc.2017-01257.


Clinical Reasoning: A 54-year-old woman with dementia, myoclonus, and ataxia.

Ali F, Murray JA, Adams AC, Flanagan EP.

Neurology. 2017 Jul 11;89(2):e7-e12. doi: 10.1212/WNL.0000000000004093. No abstract available.


Reduced adiposity attenuates FGF21 mediated metabolic improvements in the Siberian hamster.

Lewis JE, Samms RJ, Cooper S, Luckett JC, Perkins AC, Adams AC, Tsintzas K, Ebling FJP.

Sci Rep. 2017 Jun 26;7(1):4238. doi: 10.1038/s41598-017-03607-x.


Precise stimulation location optimizes speech outcomes in essential tremor.

Matsumoto JY, Fossett T, Kim M, Duffy JR, Strand E, McKeon A, Lee KH, Stead M, Burnett M, Adams AC, Klassen BT.

Parkinsonism Relat Disord. 2016 Nov;32:60-65. doi: 10.1016/j.parkreldis.2016.08.017. Epub 2016 Aug 25.


Fibroblast growth factor 21 has no direct role in regulating fertility in female mice.

Singhal G, Douris N, Fish AJ, Zhang X, Adams AC, Flier JS, Pissios P, Maratos-Flier E.

Mol Metab. 2016 May 18;5(8):690-698. doi: 10.1016/j.molmet.2016.05.010. eCollection 2016 Aug.


FGF21 Improves the Adipocyte Dysfunction Related to Seipin Deficiency.

Dollet L, Levrel C, Coskun T, Le Lay S, Le May C, Ayer A, Venara Q, Adams AC, Gimeno RE, Magré J, Cariou B, Prieur X.

Diabetes. 2016 Nov;65(11):3410-3417. Epub 2016 Aug 23.


Fibroblast Growth Factor 21-Null Mice Do Not Exhibit an Impaired Response to Fasting.

Antonellis PJ, Hayes MP, Adams AC.

Front Endocrinol (Lausanne). 2016 Jun 30;7:77. doi: 10.3389/fendo.2016.00077. eCollection 2016.


The Nuclear Receptor Rev-erbα Regulates Adipose Tissue-specific FGF21 Signaling.

Jager J, Wang F, Fang B, Lim HW, Peed LC, Steger DJ, Won KJ, Kharitonenkov A, Adams AC, Lazar MA.

J Biol Chem. 2016 May 13;291(20):10867-75. doi: 10.1074/jbc.M116.719120. Epub 2016 Mar 21.


Overexpression of β-Klotho in Adipose Tissue Sensitizes Male Mice to Endogenous FGF21 and Provides Protection From Diet-Induced Obesity.

Samms RJ, Cheng CC, Kharitonenkov A, Gimeno RE, Adams AC.

Endocrinology. 2016 Apr;157(4):1467-80. doi: 10.1210/en.2015-1722. Epub 2016 Feb 22.


Fibroblast Growth Factor 21 (FGF21) Protects against High Fat Diet Induced Inflammation and Islet Hyperplasia in Pancreas.

Singhal G, Fisher FM, Chee MJ, Tan TG, El Ouaamari A, Adams AC, Najarian R, Kulkarni RN, Benoist C, Flier JS, Maratos-Flier E.

PLoS One. 2016 Feb 12;11(2):e0148252. doi: 10.1371/journal.pone.0148252. eCollection 2016.


The Sweetest Thing: Regulation of Macronutrient Preference by FGF21.

Adams AC, Gimeno RE.

Cell Metab. 2016 Feb 9;23(2):227-8. doi: 10.1016/j.cmet.2016.01.013.

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