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Items: 1 to 20 of 204


Impact of Daylight Saving Time on circadian timing system: An expert statement.

Meira E Cruz M, Miyazawa M, Manfredini R, Cardinali D, Madrid JA, Reiter R, Araujo JF, Agostinho R, Acuña-Castroviejo D.

Eur J Intern Med. 2019 Feb;60:1-3. doi: 10.1016/j.ejim.2019.01.001. Epub 2019 Jan 5. Review. No abstract available.


Targeting NLRP3 (Nucleotide-Binding Domain, Leucine-Rich-Containing Family, Pyrin Domain-Containing-3) Inflammasome in Cardiovascular Disorders.

Wang Z, Hu W, Lu C, Ma Z, Jiang S, Gu C, Acuña-Castroviejo D, Yang Y.

Arterioscler Thromb Vasc Biol. 2018 Dec;38(12):2765-2779. doi: 10.1161/ATVBAHA.118.311916.


β-RA reduces DMQ/CoQ ratio and rescues the encephalopathic phenotype in Coq9 R239X mice.

Hidalgo-Gutiérrez A, Barriocanal-Casado E, Bakkali M, Díaz-Casado ME, Sánchez-Maldonado L, Romero M, Sayed RK, Prehn C, Escames G, Duarte J, Acuña-Castroviejo D, López LC.

EMBO Mol Med. 2019 Jan;11(1). pii: e9466. doi: 10.15252/emmm.201809466.


Reduction in the levels of CoQ biosynthetic proteins is related to an increase in lifespan without evidence of hepatic mitohormesis.

Rodríguez-Hidalgo M, Luna-Sánchez M, Hidalgo-Gutiérrez A, Barriocanal-Casado E, Mascaraque C, Acuña-Castroviejo D, Rivera M, Escames G, López LC.

Sci Rep. 2018 Sep 18;8(1):14013. doi: 10.1038/s41598-018-32190-y.


Cardiometabolic impact of changing internal time during daylight saving time: a window for a deleterious role within sleep-related breathing disorders.

Meira E Cruz M, Acuña-Castroviejo D.

Intern Emerg Med. 2018 Dec;13(8):1345-1346. doi: 10.1007/s11739-018-1934-7. Epub 2018 Aug 27. No abstract available.


Melatonin Mitigates Mitochondrial Meltdown: Interactions with SIRT3.

Reiter RJ, Tan DX, Rosales-Corral S, Galano A, Jou MJ, Acuna-Castroviejo D.

Int J Mol Sci. 2018 Aug 18;19(8). pii: E2439. doi: 10.3390/ijms19082439. Review.


Analysis of Plasma MicroRNAs as Predictors and Biomarkers of Aging and Frailty in Humans.

Rusanova I, Diaz-Casado ME, Fernández-Ortiz M, Aranda-Martínez P, Guerra-Librero A, García-García FJ, Escames G, Mañas L, Acuña-Castroviejo D.

Oxid Med Cell Longev. 2018 Jul 18;2018:7671850. doi: 10.1155/2018/7671850. eCollection 2018.


The Melatonin Analog IQM316 May Induce Adult Hippocampal Neurogenesis and Preserve Recognition Memories in Mice.

Figueiro-Silva J, Antequera D, Pascual C, de la Fuente Revenga M, Volt H, Acuña-Castroviejo D, Rodríguez-Franco MI, Carro E.

Cell Transplant. 2018 Mar;27(3):423-437. doi: 10.1177/0963689717721217.


The Protective Effect of Melatonin Against Age-Associated, Sarcopenia-Dependent Tubular Aggregate Formation, Lactate Depletion, and Mitochondrial Changes.

Sayed RKA, Fernández-Ortiz M, Diaz-Casado ME, Rusanova I, Rahim I, Escames G, López LC, Mokhtar DM, Acuña-Castroviejo D.

J Gerontol A Biol Sci Med Sci. 2018 Sep 11;73(10):1330-1338. doi: 10.1093/gerona/gly059.


Combination of melatonin and rapamycin for head and neck cancer therapy: Suppression of AKT/mTOR pathway activation, and activation of mitophagy and apoptosis via mitochondrial function regulation.

Shen YQ, Guerra-Librero A, Fernandez-Gil BI, Florido J, García-López S, Martinez-Ruiz L, Mendivil-Perez M, Soto-Mercado V, Acuña-Castroviejo D, Ortega-Arellano H, Carriel V, Diaz-Casado ME, Reiter RJ, Rusanova I, Nieto A, López LC, Escames G.

J Pineal Res. 2018 Apr;64(3). doi: 10.1111/jpi.12461. Epub 2018 Jan 9.


In Vivo Determination of Mitochondrial Respiration in 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Treated Zebrafish Reveals the Efficacy of Melatonin in Restoring Mitochondrial Normalcy.

Díaz-Casado ME, Rusanova I, Aranda P, Fernández-Ortiz M, Sayed RKA, Fernández-Gil BI, Hidalgo-Gutiérrez A, Escames G, López LC, Acuña-Castroviejo D.

Zebrafish. 2018 Feb;15(1):15-26. doi: 10.1089/zeb.2017.1479. Epub 2017 Nov 29.


Effect of Melatonin Supplementation on Antioxidant Status and DNA Damage in High Intensity Trained Athletes.

Ortiz-Franco M, Planells E, Quintero B, Acuña-Castroviejo D, Rusanova I, Escames G, Molina-López J.

Int J Sports Med. 2017 Dec;38(14):1117-1125. doi: 10.1055/s-0043-119881. Epub 2017 Nov 17.


Melatonin Treatment Reduces Oxidative Damage and Normalizes Plasma Pro-Inflammatory Cytokines in Patients Suffering from Charcot-Marie-Tooth Neuropathy: A Pilot Study in Three Children.

Chahbouni M, López MDS, Molina-Carballo A, de Haro T, Muñoz-Hoyos A, Fernández-Ortiz M, Guerra-Librero A, Acuña-Castroviejo D.

Molecules. 2017 Oct 14;22(10). pii: E1728. doi: 10.3390/molecules22101728.


Genetic dissection of endothelial transcriptional activity of zebrafish aryl hydrocarbon receptors (AHRs).

Sugden WW, Leonardo-Mendonça RC, Acuña-Castroviejo D, Siekmann AF.

PLoS One. 2017 Aug 17;12(8):e0183433. doi: 10.1371/journal.pone.0183433. eCollection 2017.


Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases.

López A, Ortiz F, Doerrier C, Venegas C, Fernández-Ortiz M, Aranda P, Díaz-Casado ME, Fernández-Gil B, Barriocanal-Casado E, Escames G, López LC, Acuña-Castroviejo D.

PLoS One. 2017 Aug 11;12(8):e0183090. doi: 10.1371/journal.pone.0183090. eCollection 2017.


Melatonin, clock genes and mitochondria in sepsis.

Acuña-Castroviejo D, Rahim I, Acuña-Fernández C, Fernández-Ortiz M, Solera-Marín J, Sayed RKA, Díaz-Casado ME, Rusanova I, López LC, Escames G.

Cell Mol Life Sci. 2017 Nov;74(21):3965-3987. doi: 10.1007/s00018-017-2610-1. Epub 2017 Aug 7. Review.


Oral Mucositis: Melatonin Gel an Effective New Treatment.

Abdel Moneim AE, Guerra-Librero A, Florido J, Shen YQ, Fernández-Gil B, Acuña-Castroviejo D, Escames G.

Int J Mol Sci. 2017 May 7;18(5). pii: E1003. doi: 10.3390/ijms18051003. Review.


Melatonin enhances neural stem cell differentiation and engraftment by increasing mitochondrial function.

Mendivil-Perez M, Soto-Mercado V, Guerra-Librero A, Fernandez-Gil BI, Florido J, Shen YQ, Tejada MA, Capilla-Gonzalez V, Rusanova I, Garcia-Verdugo JM, Acuña-Castroviejo D, López LC, Velez-Pardo C, Jimenez-Del-Rio M, Ferrer JM, Escames G.

J Pineal Res. 2017 Sep;63(2). doi: 10.1111/jpi.12415. Epub 2017 May 18.


Melatonin, a Full Service Anti-Cancer Agent: Inhibition of Initiation, Progression and Metastasis.

Reiter RJ, Rosales-Corral SA, Tan DX, Acuna-Castroviejo D, Qin L, Yang SF, Xu K.

Int J Mol Sci. 2017 Apr 17;18(4). pii: E843. doi: 10.3390/ijms18040843. Review.


Melatonin protects rats from radiotherapy-induced small intestine toxicity.

Fernández-Gil B, Moneim AE, Ortiz F, Shen YQ, Soto-Mercado V, Mendivil-Perez M, Guerra-Librero A, Acuña-Castroviejo D, Molina-Navarro MM, García-Verdugo JM, Sayed RK, Florido J, Luna JD, López LC, Escames G.

PLoS One. 2017 Apr 12;12(4):e0174474. doi: 10.1371/journal.pone.0174474. eCollection 2017.

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