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Items: 1 to 20 of 134

1.

Longitudinal serum S100β and brain aging in the Lothian Birth Cohort 1936.

Cox SR, Allerhand M, Ritchie SJ, Muñoz Maniega S, Valdés Hernández M, Harris SE, Dickie DA, Anblagan D, Aribisala BS, Morris Z, Sherwood R, Abbott NJ, Starr JM, Bastin ME, Wardlaw JM, Deary IJ.

Neurobiol Aging. 2018 Sep;69:274-282. doi: 10.1016/j.neurobiolaging.2018.05.029. Epub 2018 May 31.

2.

The role of brain barriers in fluid movement in the CNS: is there a 'glymphatic' system?

Abbott NJ, Pizzo ME, Preston JE, Janigro D, Thorne RG.

Acta Neuropathol. 2018 Mar;135(3):387-407. doi: 10.1007/s00401-018-1812-4. Epub 2018 Feb 10. Review.

PMID:
29428972
3.

Molecular characterization of perivascular drainage pathways in the murine brain.

Hannocks MJ, Pizzo ME, Huppert J, Deshpande T, Abbott NJ, Thorne RG, Sorokin L.

J Cereb Blood Flow Metab. 2018 Apr;38(4):669-686. doi: 10.1177/0271678X17749689. Epub 2017 Dec 28.

PMID:
29283289
4.

TRPA1-FGFR2 binding event is a regulatory oncogenic driver modulated by miRNA-142-3p.

Berrout J, Kyriakopoulou E, Moparthi L, Hogea AS, Berrout L, Ivan C, Lorger M, Boyle J, Peers C, Muench S, Gomez JE, Hu X, Hurst C, Hall T, Umamaheswaran S, Wesley L, Gagea M, Shires M, Manfield I, Knowles MA, Davies S, Suhling K, Gonzalez YT, Carragher N, Macleod K, Abbott NJ, Calin GA, Gamper N, Zygmunt PM, Timsah Z.

Nat Commun. 2017 Oct 16;8(1):947. doi: 10.1038/s41467-017-00983-w.

5.

Intrathecal antibody distribution in the rat brain: surface diffusion, perivascular transport and osmotic enhancement of delivery.

Pizzo ME, Wolak DJ, Kumar NN, Brunette E, Brunnquell CL, Hannocks MJ, Abbott NJ, Meyerand ME, Sorokin L, Stanimirovic DB, Thorne RG.

J Physiol. 2018 Feb 1;596(3):445-475. doi: 10.1113/JP275105. Epub 2017 Dec 18.

PMID:
29023798
6.

Improved Method for the Establishment of an In Vitro Blood-Brain Barrier Model Based on Porcine Brain Endothelial Cells.

Nielsen SSE, Siupka P, Georgian A, Preston JE, Tóth AE, Yusof SR, Abbott NJ, Nielsen MS.

J Vis Exp. 2017 Sep 24;(127). doi: 10.3791/56277.

PMID:
28994773
7.

The blood-brain barrier in psychosis.

Pollak TA, Drndarski S, Stone JM, David AS, McGuire P, Abbott NJ.

Lancet Psychiatry. 2018 Jan;5(1):79-92. doi: 10.1016/S2215-0366(17)30293-6. Epub 2017 Aug 3. Review.

PMID:
28781208
8.

Uptake and metabolism of sulphated steroids by the blood-brain barrier in the adult male rat.

Qaiser MZ, Dolman DEM, Begley DJ, Abbott NJ, Cazacu-Davidescu M, Corol DI, Fry JP.

J Neurochem. 2017 Sep;142(5):672-685. doi: 10.1111/jnc.14117. Epub 2017 Aug 3.

9.

Impact of capillary flow hydrodynamics on carrier-mediated transport of opioid derivatives at the blood-brain barrier, based on pH-dependent Michaelis-Menten and Crone-Renkin analyses.

Yusof SR, Abbott NJ, Avdeef A.

Eur J Pharm Sci. 2017 Aug 30;106:274-286. doi: 10.1016/j.ejps.2017.06.016. Epub 2017 Jun 11.

PMID:
28614733
10.

Sustained left ventricular outflow tract ventricular tachycardia following transcatheter aortic valve replacement.

Seto AH, Abbott NJ, Makkar RR, Salazar MA.

Eur Heart J. 2017 Jun 7;38(22):1776. doi: 10.1093/eurheartj/ehx129. No abstract available.

PMID:
28369252
11.

Bidirectional apical-basal traffic of the cation-independent mannose-6-phosphate receptor in brain endothelial cells.

Siupka P, Hersom MN, Lykke-Hartmann K, Johnsen KB, Thomsen LB, Andresen TL, Moos T, Abbott NJ, Brodin B, Nielsen MS.

J Cereb Blood Flow Metab. 2017 Jul;37(7):2598-2613. doi: 10.1177/0271678X17700665. Epub 2017 Mar 24.

12.

In vitro models of the blood-brain barrier: An overview of commonly used brain endothelial cell culture models and guidelines for their use.

Helms HC, Abbott NJ, Burek M, Cecchelli R, Couraud PO, Deli MA, Förster C, Galla HJ, Romero IA, Shusta EV, Stebbins MJ, Vandenhaute E, Weksler B, Brodin B.

J Cereb Blood Flow Metab. 2016 May;36(5):862-90. doi: 10.1177/0271678X16630991. Epub 2016 Feb 11. Review.

13.

Translocation of LRP1 targeted carbon nanotubes of different diameters across the blood-brain barrier in vitro and in vivo.

Kafa H, Wang JT, Rubio N, Klippstein R, Costa PM, Hassan HA, Sosabowski JK, Bansal SS, Preston JE, Abbott NJ, Al-Jamal KT.

J Control Release. 2016 Mar 10;225:217-29. doi: 10.1016/j.jconrel.2016.01.031. Epub 2016 Jan 23.

14.

LRP-1-mediated intracellular antibody delivery to the Central Nervous System.

Tian X, Nyberg S, S Sharp P, Madsen J, Daneshpour N, Armes SP, Berwick J, Azzouz M, Shaw P, Abbott NJ, Battaglia G.

Sci Rep. 2015 Jul 20;5:11990. doi: 10.1038/srep11990.

15.

The interaction of carbon nanotubes with an in vitro blood-brain barrier model and mouse brain in vivo.

Kafa H, Wang JT, Rubio N, Venner K, Anderson G, Pach E, Ballesteros B, Preston JE, Abbott NJ, Al-Jamal KT.

Biomaterials. 2015;53:437-52. doi: 10.1016/j.biomaterials.2015.02.083. Epub 2015 Mar 19.

16.

Characterization of a novel brain barrier ex vivo insect-based P-glycoprotein screening model.

Andersson O, Badisco L, Hansen AH, Hansen SH, Hellman K, Nielsen PA, Olsen LR, Verdonck R, Abbott NJ, Vanden Broeck J, Andersson G.

Pharmacol Res Perspect. 2014 Aug;2(4):e00050. doi: 10.1002/prp2.50. Epub 2014 Jun 9.

17.

Primary porcine brain microvessel endothelial cell isolation and culture.

Patabendige A, Abbott NJ.

Curr Protoc Neurosci. 2014 Oct 8;69:3.27.1-17. doi: 10.1002/0471142301.ns0327s69.

PMID:
25297692
18.

In vitro porcine blood-brain barrier model for permeability studies: pCEL-X software pKa(FLUX) method for aqueous boundary layer correction and detailed data analysis.

Yusof SR, Avdeef A, Abbott NJ.

Eur J Pharm Sci. 2014 Dec 18;65:98-111. doi: 10.1016/j.ejps.2014.09.009. Epub 2014 Sep 18.

19.

A high-content small molecule screen identifies sensitivity of glioblastoma stem cells to inhibition of polo-like kinase 1.

Danovi D, Folarin A, Gogolok S, Ender C, Elbatsh AM, Engström PG, Stricker SH, Gagrica S, Georgian A, Yu D, U KP, Harvey KJ, Ferretti P, Paddison PJ, Preston JE, Abbott NJ, Bertone P, Smith A, Pollard SM.

PLoS One. 2013 Oct 30;8(10):e77053. doi: 10.1371/journal.pone.0077053. eCollection 2013.

20.

A multi-system approach assessing the interaction of anticonvulsants with P-gp.

Dickens D, Yusof SR, Abbott NJ, Weksler B, Romero IA, Couraud PO, Alfirevic A, Pirmohamed M, Owen A.

PLoS One. 2013 May 31;8(5):e64854. doi: 10.1371/journal.pone.0064854. Print 2013.

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