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Items: 1 to 20 of 32

1.

Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.

Wilkinson B, Evgrafov OV, Zheng D, Hartel N, Knowles JA, Graham NA, Ichida JK, Coba MP.

Biol Psychiatry. 2018 May 23. pii: S0006-3223(18)31523-3. doi: 10.1016/j.biopsych.2018.05.009. [Epub ahead of print]

PMID:
29961565
2.

CRISPR-Cas9 screens in human cells and primary neurons identify modifiers of C9ORF72 dipeptide-repeat-protein toxicity.

Kramer NJ, Haney MS, Morgens DW, Jovičić A, Couthouis J, Li A, Ousey J, Ma R, Bieri G, Tsui CK, Shi Y, Hertz NT, Tessier-Lavigne M, Ichida JK, Bassik MC, Gitler AD.

Nat Genet. 2018 Apr;50(4):603-612. doi: 10.1038/s41588-018-0070-7. Epub 2018 Mar 5.

PMID:
29507424
3.

Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons.

Shi Y, Lin S, Staats KA, Li Y, Chang WH, Hung ST, Hendricks E, Linares GR, Wang Y, Son EY, Wen X, Kisler K, Wilkinson B, Menendez L, Sugawara T, Woolwine P, Huang M, Cowan MJ, Ge B, Koutsodendris N, Sandor KP, Komberg J, Vangoor VR, Senthilkumar K, Hennes V, Seah C, Nelson AR, Cheng TY, Lee SJ, August PR, Chen JA, Wisniewski N, Hanson-Smith V, Belgard TG, Zhang A, Coba M, Grunseich C, Ward ME, van den Berg LH, Pasterkamp RJ, Trotti D, Zlokovic BV, Ichida JK.

Nat Med. 2018 Mar;24(3):313-325. doi: 10.1038/nm.4490. Epub 2018 Feb 5.

PMID:
29400714
4.

Neuroleptics as therapeutic compounds stabilizing neuromuscular transmission in amyotrophic lateral sclerosis.

Patten SA, Aggad D, Martinez J, Tremblay E, Petrillo J, Armstrong GA, La Fontaine A, Maios C, Liao M, Ciura S, Wen XY, Rafuse V, Ichida J, Zinman L, Julien JP, Kabashi E, Robitaille R, Korngut L, Parker JA, Drapeau P.

JCI Insight. 2017 Nov 16;2(22). pii: 97152. doi: 10.1172/jci.insight.97152. [Epub ahead of print]

5.

Compartmentalized embryoid body culture for induction of spatially patterned differentiation.

Kaneda S, Kawada J, Akutsu H, Ichida J, Ikeuchi Y, Fujii T.

Biomicrofluidics. 2017 Aug 2;11(4):041101. doi: 10.1063/1.4994989. eCollection 2017 Jul.

6.

Human Induced Pluripotent Stem Cell-Derived Motor Neuron Transplant for Neuromuscular Atrophy in a Mouse Model of Sciatic Nerve Injury.

Pepper JP, Wang TV, Hennes V, Sun SY, Ichida JK.

JAMA Facial Plast Surg. 2017 May 1;19(3):197-205. doi: 10.1001/jamafacial.2016.1544.

7.

Iroquois Proteins Promote Skeletal Joint Formation by Maintaining Chondrocytes in an Immature State.

Askary A, Mork L, Paul S, He X, Izuhara AK, Gopalakrishnan S, Ichida JK, McMahon AP, Dabizljevic S, Dale R, Mariani FV, Crump JG.

Dev Cell. 2015 Nov 9;35(3):358-65. doi: 10.1016/j.devcel.2015.10.004.

8.

New approaches for direct conversion of patient fibroblasts into neural cells.

Gopalakrishnan S, Hor P, Ichida JK.

Brain Res. 2017 Feb 1;1656:2-13. doi: 10.1016/j.brainres.2015.10.012. Epub 2015 Oct 16. Review.

9.

Small Molecules Take a Big Step by Converting Fibroblasts into Neurons.

Babos K, Ichida JK.

Cell Stem Cell. 2015 Aug 6;17(2):127-9. doi: 10.1016/j.stem.2015.07.018.

10.

Central role for PICALM in amyloid-β blood-brain barrier transcytosis and clearance.

Zhao Z, Sagare AP, Ma Q, Halliday MR, Kong P, Kisler K, Winkler EA, Ramanathan A, Kanekiyo T, Bu G, Owens NC, Rege SV, Si G, Ahuja A, Zhu D, Miller CA, Schneider JA, Maeda M, Maeda T, Sugawara T, Ichida JK, Zlokovic BV.

Nat Neurosci. 2015 Jul;18(7):978-87. doi: 10.1038/nn.4025. Epub 2015 May 25.

11.

Probing disorders of the nervous system using reprogramming approaches.

Ichida JK, Kiskinis E.

EMBO J. 2015 Jun 3;34(11):1456-77. doi: 10.15252/embj.201591267. Epub 2015 Apr 29. Review.

12.

Motoneurons derived from induced pluripotent stem cells develop mature phenotypes typical of endogenous spinal motoneurons.

Toma JS, Shettar BC, Chipman PH, Pinto DM, Borowska JP, Ichida JK, Fawcett JP, Zhang Y, Eggan K, Rafuse VF.

J Neurosci. 2015 Jan 21;35(3):1291-306. doi: 10.1523/JNEUROSCI.2126-14.2015.

13.

Antisense proline-arginine RAN dipeptides linked to C9ORF72-ALS/FTD form toxic nuclear aggregates that initiate in vitro and in vivo neuronal death.

Wen X, Tan W, Westergard T, Krishnamurthy K, Markandaiah SS, Shi Y, Lin S, Shneider NA, Monaghan J, Pandey UB, Pasinelli P, Ichida JK, Trotti D.

Neuron. 2014 Dec 17;84(6):1213-25. doi: 10.1016/j.neuron.2014.12.010.

14.

Modeling pain in vitro using nociceptor neurons reprogrammed from fibroblasts.

Wainger BJ, Buttermore ED, Oliveira JT, Mellin C, Lee S, Saber WA, Wang AJ, Ichida JK, Chiu IM, Barrett L, Huebner EA, Bilgin C, Tsujimoto N, Brenneis C, Kapur K, Rubin LL, Eggan K, Woolf CJ.

Nat Neurosci. 2015 Jan;18(1):17-24. doi: 10.1038/nn.3886. Epub 2014 Nov 24.

15.

Notch inhibition allows oncogene-independent generation of iPS cells.

Ichida JK, Tcw J, Williams LA, Carter AC, Shi Y, Moura MT, Ziller M, Singh S, Amabile G, Bock C, Umezawa A, Rubin LL, Bradner JE, Akutsu H, Meissner A, Eggan K.

Nat Chem Biol. 2014 Aug;10(8):632-639. doi: 10.1038/nchembio.1552. Epub 2014 Jun 22. Erratum in: Nat Chem Biol. 2014 Dec;10(12):1074. T C W, Julia [corrected to TCW, Julia].

16.

Ketamine exposure in early development impairs specification of the primary germ cell layers.

Akeju O, Davis-Dusenbery BN, Cassel SH, Ichida JK, Eggan K.

Neurotoxicol Teratol. 2014 May-Jun;43:59-68. doi: 10.1016/j.ntt.2014.04.001. Epub 2014 Apr 16.

17.

Pathways disrupted in human ALS motor neurons identified through genetic correction of mutant SOD1.

Kiskinis E, Sandoe J, Williams LA, Boulting GL, Moccia R, Wainger BJ, Han S, Peng T, Thams S, Mikkilineni S, Mellin C, Merkle FT, Davis-Dusenbery BN, Ziller M, Oakley D, Ichida J, Di Costanzo S, Atwater N, Maeder ML, Goodwin MJ, Nemesh J, Handsaker RE, Paull D, Noggle S, McCarroll SA, Joung JK, Woolf CJ, Brown RH, Eggan K.

Cell Stem Cell. 2014 Jun 5;14(6):781-95. doi: 10.1016/j.stem.2014.03.004. Epub 2014 Apr 3.

18.

Nanog-independent reprogramming to iPSCs with canonical factors.

Carter AC, Davis-Dusenbery BN, Koszka K, Ichida JK, Eggan K.

Stem Cell Reports. 2014 Jan 31;2(2):119-26. doi: 10.1016/j.stemcr.2013.12.010. eCollection 2014 Feb 11.

19.

Derivation of induced pluripotent stem cells from the baboon: a nonhuman primate model for preclinical testing of stem cell therapies.

Navara CS, Hornecker J, Grow D, Chaudhari S, Hornsby PJ, Ichida JK, Eggan K, McCarrey JR.

Cell Reprogram. 2013 Dec;15(6):495-502. doi: 10.1089/cell.2012.0093. Epub 2013 Nov 4.

20.

β-catenin functions pleiotropically in differentiation and tumorigenesis in mouse embryo-derived stem cells.

Okumura N, Akutsu H, Sugawara T, Miura T, Takezawa Y, Hosoda A, Yoshida K, Ichida JK, Yamada M, Hamatani T, Kuji N, Miyado K, Yoshimura Y, Umezawa A.

PLoS One. 2013 May 14;8(5):e63265. doi: 10.1371/journal.pone.0063265. Print 2013.

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