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The role of CCR5 in directing the mobilization and biological function of CD11b+Gr1+Ly6Clow polymorphonuclear myeloid cells in cancer.

Karin N, Razon H.

Cancer Immunol Immunother. 2018 Sep 19. doi: 10.1007/s00262-018-2245-6. [Epub ahead of print] Review.


Autoantibodies to Chemokines and Cytokines Participate in the Regulation of Cancer and Autoimmunity.

Karin N.

Front Immunol. 2018 Mar 29;9:623. doi: 10.3389/fimmu.2018.00623. eCollection 2018. Review.


Correction: Dissecting the Autocrine and Paracrine Roles of the CCR2-CCL2 Axis in Tumor Survival and Angiogenesis.

Izhak L, Wildbaum G, Jung S, Stein A, Shaked Y, Karin N.

PLoS One. 2018 Apr 12;13(4):e0195170. doi: 10.1371/journal.pone.0195170. eCollection 2018.


Chemokines and cancer: new immune checkpoints for cancer therapy.

Karin N.

Curr Opin Immunol. 2018 Apr;51:140-145. doi: 10.1016/j.coi.2018.03.004. Epub 2018 Mar 24. Review.


CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis.

Zohar Y, Wildbaum G, Novak R, Salzman AL, Thelen M, Alon R, Barsheshet Y, Karp CL, Karin N.

J Clin Invest. 2018 Mar 1;128(3):1200-1201. doi: 10.1172/JCI120358. Epub 2018 Mar 1. No abstract available.


Correction: Predominant Expression of CCL2 at the Tumor Site of Prostate Cancer Patients Directs a Selective Loss of Immunological Tolerance to CCL2 That Could Be Amplified in a Beneficial Manner.

Izhak L, Wildbaum G, Weinberg U, Shaked Y, Alami J, Dumont D, Friedman B, Stein A, Karin N.

J Immunol. 2018 Apr 1;200(7):2509-2510. doi: 10.4049/jimmunol.1800167. Epub 2018 Feb 23. No abstract available.


Correction: A Fusion Protein Encoding the Second Extracellular Domain of CCR5 Arrests Chemokine-Induced Cosignaling and Effectively Suppresses Ongoing Experimental Autoimmune Encephalomyelitis.

Sapir Y, Vitenshtein A, Barsheshet Y, Zohar Y, Wildbaum G, Karin N.

J Immunol. 2018 Apr 1;200(7):2507-2508. doi: 10.4049/jimmunol.1800166. Epub 2018 Feb 21. No abstract available.


Chemokines beyond chemo-attraction: CXCL10 and its significant role in cancer and autoimmunity.

Karin N, Razon H.

Cytokine. 2018 Sep;109:24-28. doi: 10.1016/j.cyto.2018.02.012. Epub 2018 Feb 12.


CCR5 Directs the Mobilization of CD11b+Gr1+Ly6Clow Polymorphonuclear Myeloid Cells from the Bone Marrow to the Blood to Support Tumor Development.

Hawila E, Razon H, Wildbaum G, Blattner C, Sapir Y, Shaked Y, Umansky V, Karin N.

Cell Rep. 2017 Nov 21;21(8):2212-2222. doi: 10.1016/j.celrep.2017.10.104.


CCR5+ Myeloid-Derived Suppressor Cells Are Enriched and Activated in Melanoma Lesions.

Blattner C, Fleming V, Weber R, Himmelhan B, Altevogt P, Gebhardt C, Schulze TJ, Razon H, Hawila E, Wildbaum G, Utikal J, Karin N, Umansky V.

Cancer Res. 2018 Jan 1;78(1):157-167. doi: 10.1158/0008-5472.CAN-17-0348. Epub 2017 Oct 31.


CXCL11-dependent induction of FOXP3-negative regulatory T cells suppresses autoimmune encephalomyelitis.

Zohar Y, Wildbaum G, Novak R, Salzman AL, Thelen M, Alon R, Barsheshet Y, Karp CL, Karin N.

J Clin Invest. 2017 Oct 2;127(10):3913. doi: 10.1172/JCI97015. Epub 2017 Aug 28. No abstract available.


CCR8+FOXp3+ Treg cells as master drivers of immune regulation.

Barsheshet Y, Wildbaum G, Levy E, Vitenshtein A, Akinseye C, Griggs J, Lira SA, Karin N.

Proc Natl Acad Sci U S A. 2017 Jun 6;114(23):6086-6091. doi: 10.1073/pnas.1621280114. Epub 2017 May 22.


The antiangiogenic role of the pro-inflammatory cytokine interleukin-31.

Davidi S, Fremder E, Kan T, Raviv Z, Timaner M, Karin N, Hershkovitz D, Arohneim A, Shaked Y.

Oncotarget. 2017 Mar 7;8(10):16430-16444. doi: 10.18632/oncotarget.14857.


Adoptive Transfer of mRNA-Transfected T Cells Redirected against Diabetogenic CD8 T Cells Can Prevent Diabetes.

Fishman S, Lewis MD, Siew LK, De Leenheer E, Kakabadse D, Davies J, Ziv D, Margalit A, Karin N, Gross G, Wong FS.

Mol Ther. 2017 Feb 1;25(2):456-464. doi: 10.1016/j.ymthe.2016.12.007. Epub 2017 Jan 18.


The cardiac maladaptive ATF3-dependent cross-talk between cardiomyocytes and macrophages is mediated by the IFNγ-CXCL10-CXCR3 axis.

Koren L, Barash U, Zohar Y, Karin N, Aronheim A.

Int J Cardiol. 2017 Feb 1;228:394-400. doi: 10.1016/j.ijcard.2016.11.159. Epub 2016 Nov 10.


The effect of lysophosphatidic acid using a hydrogel or collagen sponge carrier on bone healing in dogs.

Might KR, Martinez SA, Karin N, Lin G, Tarasevich B, Pool RR.

Vet Comp Orthop Traumatol. 2016 Jul 19;29(4):306-13. doi: 10.3415/VCOT-15-08-0137. Epub 2016 Jun 1.


Mechanism of action and efficacy of RX-111, a thieno[2,3-c]pyridine derivative and small molecule inhibitor of protein interaction with glycosaminoglycans (SMIGs), in delayed-type hypersensitivity, TNBS-induced colitis and experimental autoimmune encephalomyelitis.

Harris N, Koppel J, Zsila F, Juhas S, Il'kova G, Kogan FY, Lahmy O, Wildbaum G, Karin N, Zhuk R, Gregor P.

Inflamm Res. 2016 Apr;65(4):285-94. doi: 10.1007/s00011-016-0915-4. Epub 2016 Jan 21.


Biased signaling pathways via CXCR3 control the development and function of CD4+ T cell subsets.

Karin N, Wildbaum G, Thelen M.

J Leukoc Biol. 2016 Jun;99(6):857-62. doi: 10.1189/jlb.2MR0915-441R. Epub 2015 Dec 9. Review.


The Role of Chemokines in Shaping the Balance Between CD4(+) T Cell Subsets and Its Therapeutic Implications in Autoimmune and Cancer Diseases.

Karin N, Wildbaum G.

Front Immunol. 2015 Nov 30;6:609. doi: 10.3389/fimmu.2015.00609. eCollection 2015. Review.


The role of chemokines in adjusting the balance between CD4+ effector T cell subsets and FOXp3-negative regulatory T cells.

Karin N, Wildbaum G.

Int Immunopharmacol. 2015 Oct;28(2):829-35. doi: 10.1016/j.intimp.2015.03.037. Epub 2015 Apr 20. Review.


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