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J Eur Acad Dermatol Venereol. 2004 Nov;18(6):676-8.

Burning mouth syndrome: the efficacy of lipoic acid on subgroups.

Author information

1
Stomatology Clinic, II University of Medicine and Surgery, Naples, Italy. femiano@libero.it

Abstract

OBJECTIVE:

We have examined the effect of alpha-lipoic acid (ALA, tioctic acid; Tiobec), a free radical scavenger, on the discomfort of burning mouth syndrome (BMS) in patients who had used tranquillizers previously, compared with those who had not.

METHODS:

In this study we gave lipoic acid for 2 months to two groups of 20 BMS patients, one of which had previously been treated with tranquillizers.

RESULTS:

The results showed greater effectiveness of lipoic acid in BMS patients who had not previously used tranquillizers.

CONCLUSIONS:

The patients with BMS who had previously been treated with tranquillizers responded poorly to therapy with lipoic acid compared with those who had not received previous psychotropic therapy.

[Indexed for MEDLINE]

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