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Items: 12

1.

The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue.

Tomita T, Maruyama K, Saido TC, Kume H, Shinozaki K, Tokuhiro S, Capell A, Walter J, Gr├╝nberg J, Haass C, Iwatsubo T, Obata K.

Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):2025-30.

2.

Genes and mechanisms involved in beta-amyloid generation and Alzheimer's disease.

Steiner H, Capell A, Leimer U, Haass C.

Eur Arch Psychiatry Clin Neurosci. 1999;249(6):266-70. Review.

PMID:
10653281
3.
4.

[beta-amyloid cascade: current status and future directions].

Iwatsubo T.

Rinsho Shinkeigaku. 2000 Dec;40(12):1228-30. Review. Japanese.

PMID:
11464463
5.

[Beta-amyloid protein: recent progress in basic research and therapeutic approaches].

Iwatsubo T.

Rinsho Shinkeigaku. 2001 Dec;41(12):1198-200. Review. Japanese.

PMID:
12235837
6.

Presenilins and Alzheimer's disease: the role of A beta 42.

Eckman CB.

J Neural Transm Suppl. 1998;53:181-4. Review.

PMID:
9700656
7.

Presenilins and Alzheimer's disease: biological functions and pathogenic mechanisms.

Czech C, Tremp G, Pradier L.

Prog Neurobiol. 2000 Mar;60(4):363-84. Review.

PMID:
10670705
8.

[Advances in molecular biology and clinical study of amyloid precursor protein for Alzheimer's disease].

Xu BG, Wu X.

Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2004 Apr;26(2):201-9. Review. Chinese.

PMID:
15171563
9.

Molecular genetics of Alzheimer disease.

St George-Hyslop PH.

Semin Neurol. 1999;19(4):371-83. Review.

PMID:
10716660
10.

Monogenic determinants of familial Alzheimer's disease: presenilin-2 mutations.

Renbaum P, Levy-Lahad E.

Cell Mol Life Sci. 1998 Sep;54(9):910-9. Review.

PMID:
9791533
11.

Presenilins: structural aspects and posttranslational events.

Checler F.

Mol Neurobiol. 1999 Jun;19(3):255-65. Review.

PMID:
10495106
12.

A new paradigm for neurotoxicity by FAD mutants of betaAPP: a signaling abnormality.

Nishimoto I.

Neurobiol Aging. 1998 Jan-Feb;19(1 Suppl):S33-8. Review.

PMID:
9562465

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