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Items: 1 to 20 of 53

1.
2.

Polyamine analogues targeting epigenetic gene regulation.

Huang Y, Marton LJ, Woster PM, Casero RA.

Essays Biochem. 2009 Nov 4;46:95-110. doi: 10.1042/bse0460007. Review.

3.

Reversible inhibitors of LSD1 as therapeutic agents in acute myeloid leukemia: clinical significance and progress to date.

Mould DP, McGonagle AE, Wiseman DH, Williams EL, Jordan AM.

Med Res Rev. 2015 May;35(3):586-618. doi: 10.1002/med.21334. Review.

PMID:
25418875
4.

A Systematic Review of Histone Lysine-Specific Demethylase 1 and Its Inhibitors.

Zheng YC, Ma J, Wang Z, Li J, Jiang B, Zhou W, Shi X, Wang X, Zhao W, Liu HM.

Med Res Rev. 2015 Sep;35(5):1032-71. doi: 10.1002/med.21350. Review.

PMID:
25990136
5.

Medicinal chemistry insights in the discovery of novel LSD1 inhibitors.

Wang X, Huang B, Suzuki T, Liu X, Zhan P.

Epigenomics. 2015;7(8):1379-96. doi: 10.2217/epi.15.86. Review.

PMID:
26646727
6.

Targeting histone methyltransferases and demethylases in clinical trials for cancer therapy.

Morera L, Lübbert M, Jung M.

Clin Epigenetics. 2016 May 24;8:57. doi: 10.1186/s13148-016-0223-4. Review.

7.

Lysine-specific histone demethylase 1 (LSD1): A potential molecular target for tumor therapy.

Chen Y, Jie W, Yan W, Zhou K, Xiao Y.

Crit Rev Eukaryot Gene Expr. 2012;22(1):53-9. Review.

PMID:
22339659
8.

The histone LSD1 demethylase in stemness and cancer transcription programs.

Amente S, Lania L, Majello B.

Biochim Biophys Acta. 2013 Oct;1829(10):981-6. doi: 10.1016/j.bbagrm.2013.05.002. Review.

9.

Epigenetic Therapy in Acute Myeloid Leukemia: Current and Future Directions.

Kim TK, Gore SD, Zeidan AM.

Semin Hematol. 2015 Jul;52(3):172-83. doi: 10.1053/j.seminhematol.2015.04.003. Review.

PMID:
26111464
10.

Small molecule epigenetic inhibitors targeted to histone lysine methyltransferases and demethylases.

Wang Z, Patel DJ.

Q Rev Biophys. 2013 Nov;46(4):349-73. doi: 10.1017/S0033583513000085. Review.

11.

Mechanisms involved in the regulation of histone lysine demethylases.

Lan F, Nottke AC, Shi Y.

Curr Opin Cell Biol. 2008 Jun;20(3):316-25. doi: 10.1016/j.ceb.2008.03.004. Review.

12.

[Histone demethylase LSD1 and its biological functions].

Shao GB, Huang XJ, Gong AH, Zhang ZJ, Lu RZ, Sang JR.

Yi Chuan. 2010 Apr;32(4):331-8. Review. Chinese.

PMID:
20423886
13.

Epigenetic regulators and their impact on therapy in acute myeloid leukemia.

Pastore F, Levine RL.

Haematologica. 2016 Mar;101(3):269-78. doi: 10.3324/haematol.2015.140822. Review.

14.

Histone deacetylase inhibitors for the treatment of myelodysplastic syndrome and acute myeloid leukemia.

Quintás-Cardama A, Santos FP, Garcia-Manero G.

Leukemia. 2011 Feb;25(2):226-35. doi: 10.1038/leu.2010.276. Review.

PMID:
21116282
15.

Regulation of histone H3K4 methylation in brain development and disease.

Shen E, Shulha H, Weng Z, Akbarian S.

Philos Trans R Soc Lond B Biol Sci. 2014 Sep 26;369(1652). pii: 20130514. doi: 10.1098/rstb.2013.0514. Review.

16.

Histone H3K4 demethylases are essential in development and differentiation.

Benevolenskaya EV.

Biochem Cell Biol. 2007 Aug;85(4):435-43. Review.

PMID:
17713579
17.

Demethylation and re-expression of epigenetically silenced tumor suppressor genes: sensitization of cancer cells by combination therapy.

Sarkar S, Goldgar S, Byler S, Rosenthal S, Heerboth S.

Epigenomics. 2013 Feb;5(1):87-94. doi: 10.2217/epi.12.68. Review.

PMID:
23414323
18.

Histone lysine methylation and demethylation pathways in cancer.

Varier RA, Timmers HT.

Biochim Biophys Acta. 2011 Jan;1815(1):75-89. doi: 10.1016/j.bbcan.2010.10.002. Review.

PMID:
20951770
19.

Epigenetic regulation of adipogenesis by histone methylation.

Ge K.

Biochim Biophys Acta. 2012 Jul;1819(7):727-32. doi: 10.1016/j.bbagrm.2011.12.008. Review.

20.

Epigenetic control of cytokine gene expression: regulation of the TNF/LT locus and T helper cell differentiation.

Falvo JV, Jasenosky LD, Kruidenier L, Goldfeld AE.

Adv Immunol. 2013;118:37-128. doi: 10.1016/B978-0-12-407708-9.00002-9. Review.

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