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Items: 1 to 20 of 45

1.

Translational synthetic chemistry.

Kesavan S, Marcaurelle LA.

Nat Chem Biol. 2013 Apr;9(4):210-3. doi: 10.1038/nchembio.1207. No abstract available.

PMID:
23508175
2.

Targeting the Hedgehog Signaling Pathway with Small Molecules from Natural Sources.

Petricci E, Manetti F.

Curr Med Chem. 2015;22(35):4058-90. Review.

PMID:
26337106
3.

Targeting protein-protein interactions for therapeutic intervention: a challenge for the future.

Zinzalla G, Thurston DE.

Future Med Chem. 2009 Apr;1(1):65-93. doi: 10.4155/fmc.09.12. Review.

4.

Natural products as lead structures: chemical transformations to create lead-like libraries.

Pascolutti M, Quinn RJ.

Drug Discov Today. 2014 Mar;19(3):215-21. doi: 10.1016/j.drudis.2013.10.013. Epub 2013 Oct 27. Review.

5.

Target profiling of small molecules by chemical proteomics.

Rix U, Superti-Furga G.

Nat Chem Biol. 2009 Sep;5(9):616-24. doi: 10.1038/nchembio.216. Review.

PMID:
19690537
6.

Drugging the "undruggable".

Verdine GL.

Harvey Lect. 2006-2007;102:1-15. Review. No abstract available.

PMID:
20166561
7.

Natural products as chemical probes.

Carlson EE.

ACS Chem Biol. 2010 Jul 16;5(7):639-53. doi: 10.1021/cb100105c. Review.

8.

The role of HTS in drug discovery at the University of Michigan.

Larsen MJ, Larsen SD, Fribley A, Grembecka J, Homan K, Mapp A, Haak A, Nikolovska-Coleska Z, Stuckey JA, Sun D, Sherman DH.

Comb Chem High Throughput Screen. 2014 Mar;17(3):210-30. Review.

9.

[Structural diversity oriented synthesis to explore the living world].

Wong YS.

Med Sci (Paris). 2015 Jan;31(1):93-7. doi: 10.1051/medsci/20153101018. Epub 2015 Feb 6. Review. French.

10.

Macrocycles as protein-protein interaction inhibitors.

Dougherty PG, Qian Z, Pei D.

Biochem J. 2017 Mar 15;474(7):1109-1125. doi: 10.1042/BCJ20160619. Review.

PMID:
28298556
11.

Industrial natural product chemistry for drug discovery and development.

Bauer A, Brönstrup M.

Nat Prod Rep. 2014 Jan;31(1):35-60. doi: 10.1039/c3np70058e. Review.

PMID:
24142193
12.

Integrating virtual screening and combinatorial chemistry for accelerated drug discovery.

López-Vallejo F, Caulfield T, Martínez-Mayorga K, Giulianotti MA, Nefzi A, Houghten RA, Medina-Franco JL.

Comb Chem High Throughput Screen. 2011 Jul;14(6):475-87. Review.

PMID:
21521151
13.

From Protein Communication to Drug Discovery.

Persico M, Di Dato A, Orteca N, Fattorusso C, Novellino E, Andreoli M, Ferlini C.

Curr Top Med Chem. 2015;15(20):2019-31. Review.

PMID:
25986690
14.

Target identification for biologically active small molecules using chemical biology approaches.

Lee H, Lee JW.

Arch Pharm Res. 2016 Sep;39(9):1193-201. doi: 10.1007/s12272-016-0791-z. Epub 2016 Jul 8. Review.

PMID:
27387321
15.

Role of natural product diversity in chemical biology.

Hong J.

Curr Opin Chem Biol. 2011 Jun;15(3):350-4. doi: 10.1016/j.cbpa.2011.03.004. Epub 2011 Apr 12. Review.

16.

Natural products as leads to potential drugs: an old process or the new hope for drug discovery?

Newman DJ.

J Med Chem. 2008 May 8;51(9):2589-99. doi: 10.1021/jm0704090. Epub 2008 Apr 5. Review. No abstract available.

PMID:
18393402
17.

Recent Progress in Histone Demethylase Inhibitors.

McAllister TE, England KS, Hopkinson RJ, Brennan PE, Kawamura A, Schofield CJ.

J Med Chem. 2016 Feb 25;59(4):1308-29. doi: 10.1021/acs.jmedchem.5b01758. Epub 2016 Feb 2. Review.

PMID:
26710088
18.

Application of natural product-inspired diversity-oriented synthesis to drug discovery.

Marcaurelle LA, Johannes CW.

Prog Drug Res. 2008;66:187, 189-216. Review.

PMID:
18416306
19.

Utilizing diversity-oriented synthesis in antimicrobial drug discovery.

Comer E, Duvall JR, duPont Lee M 4th.

Future Med Chem. 2014;6(17):1927-42. doi: 10.4155/fmc.14.111. Review.

PMID:
25495985
20.

Reverse Pharmacognosy and Reverse Pharmacology; Two Closely Related Approaches for Drug Discovery Development.

Saeidnia S, Gohari AR, Manayi A.

Curr Pharm Biotechnol. 2016;17(11):1016-22. Review.

PMID:
27396403

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