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Items: 1 to 20 of 38

1.

Targeting chromatin readers.

James LI, Frye SV.

Clin Pharmacol Ther. 2013 Apr;93(4):312-4. doi: 10.1038/clpt.2013.6. Epub 2013 Jan 17. Review.

2.

Selective targeting of epigenetic reader domains.

Greschik H, Schüle R, Günther T.

Expert Opin Drug Discov. 2017 May;12(5):449-463. doi: 10.1080/17460441.2017.1303474. Epub 2017 Mar 14. Review.

PMID:
28277835
3.

Drugging Chromatin in Cancer: Recent Advances and Novel Approaches.

Cai SF, Chen CW, Armstrong SA.

Mol Cell. 2015 Nov 19;60(4):561-70. doi: 10.1016/j.molcel.2015.10.042. Review.

4.

Marked for death: targeting epigenetic changes in cancer.

Pfister SX, Ashworth A.

Nat Rev Drug Discov. 2017 Apr;16(4):241-263. doi: 10.1038/nrd.2016.256. Epub 2017 Mar 10. Review.

PMID:
28280262
5.

Targeting epigenetic regulators for cancer therapy.

Wee S, Dhanak D, Li H, Armstrong SA, Copeland RA, Sims R, Baylin SB, Liu XS, Schweizer L.

Ann N Y Acad Sci. 2014 Feb;1309:30-6. doi: 10.1111/nyas.12356. Review.

PMID:
24571255
6.

Emerging therapeutic targets in human acute myeloid leukemia (part 2) - bromodomain inhibition should be considered as a possible strategy for various patient subsets.

Reikvam H, Hoang TT, Bruserud Ø.

Expert Rev Hematol. 2015 Jun;8(3):315-27. doi: 10.1586/17474086.2015.1036025. Epub 2015 Apr 22. Review.

PMID:
25901742
7.

Bromodomains: Structure, function and pharmacology of inhibition.

Ferri E, Petosa C, McKenna CE.

Biochem Pharmacol. 2016 Apr 15;106:1-18. doi: 10.1016/j.bcp.2015.12.005. Epub 2015 Dec 18. Review.

PMID:
26707800
8.

Epigenetic control of cardiovascular health by nutritional polyphenols involves multiple chromatin-modifying writer-reader-eraser proteins.

Declerck K, Szarc vel Szic K, Palagani A, Heyninck K, Haegeman G, Morand C, Milenkovic D, Vanden Berghe W.

Curr Top Med Chem. 2016;16(7):788-806. Review.

PMID:
26303416
9.

[Targeted epigenetic therapy of cancer. Achievements and perspectives].

Valdespino-Gómez VM, Valdespino-Castillo VE.

Cir Cir. 2012 Sep-Oct;80(5):470-80. Review. Spanish.

PMID:
23351455
10.

Targeting protein-protein interaction by small molecules.

Jin L, Wang W, Fang G.

Annu Rev Pharmacol Toxicol. 2014;54:435-56. doi: 10.1146/annurev-pharmtox-011613-140028. Epub 2013 Oct 21. Review.

PMID:
24160698
11.

Chromatin as a target for the DNA-binding anticancer drugs.

Majumder P, Pradhan SK, Devi PG, Pal S, Dasgupta D.

Subcell Biochem. 2007;41:145-89. Review.

PMID:
17484128
12.

Targeting epigenetic networks with polypharmacology: a new avenue to tackle cancer.

Franci G, Miceli M, Altucci L.

Epigenomics. 2010 Dec;2(6):731-42. doi: 10.2217/epi.10.62. Review.

PMID:
22122079
13.

Role of Histone Acetylation in Cell Cycle Regulation.

Koprinarova M, Schnekenburger M, Diederich M.

Curr Top Med Chem. 2016;16(7):732-44. Review.

PMID:
26303420
14.

Targeting epigenetics in nervous system disease.

Zhang R, Lu J, Kong X, Jin L, Luo C.

CNS Neurol Disord Drug Targets. 2013 Feb 1;12(1):126-41. Review.

PMID:
23244434
16.

Epigenetic drugs against cancer: an evolving landscape.

Di Costanzo A, Del Gaudio N, Migliaccio A, Altucci L.

Arch Toxicol. 2014 Sep;88(9):1651-68. doi: 10.1007/s00204-014-1315-6. Epub 2014 Aug 2. Review.

PMID:
25085708
17.

Histone profiles in cancer.

Riedel SS, Neff T, Bernt KM.

Pharmacol Ther. 2015 Oct;154:87-109. doi: 10.1016/j.pharmthera.2015.07.004. Epub 2015 Jul 22. Review.

PMID:
26210403
18.

Targeting Chromatin-Mediated Transcriptional Control of Gene Expression in Non-Small Cell Lung Cancer Therapy: Preclinical Rationale and Clinical Results.

Pasini A, Delmonte A, Tesei A, Calistri D, Giordano E.

Drugs. 2015 Oct;75(15):1757-71. doi: 10.1007/s40265-015-0461-3. Review.

PMID:
26347133
19.

Mind the methyl: methyllysine binding proteins in epigenetic regulation.

Wagner T, Robaa D, Sippl W, Jung M.

ChemMedChem. 2014 Mar;9(3):466-83. doi: 10.1002/cmdc.201300422. Epub 2014 Jan 21. Review.

PMID:
24449612
20.

Modular paths to 'decoding' and 'wiping' histone lysine methylation.

Kustatscher G, Ladurner AG.

Curr Opin Chem Biol. 2007 Dec;11(6):628-35. Epub 2007 Nov 7. Review.

PMID:
17988933

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