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Items: 9

1.

Monitoring tumorigenesis and senescence in vivo with a p16(INK4a)-luciferase model.

Burd CE, Sorrentino JA, Clark KS, Darr DB, Krishnamurthy J, Deal AM, Bardeesy N, Castrillon DH, Beach DH, Sharpless NE.

Cell. 2013 Jan 17;152(1-2):340-51. doi: 10.1016/j.cell.2012.12.010.

2.

The molecular balancing act of p16(INK4a) in cancer and aging.

LaPak KM, Burd CE.

Mol Cancer Res. 2014 Feb;12(2):167-83. doi: 10.1158/1541-7786.MCR-13-0350. Epub 2013 Oct 17. Review.

3.

p16(Ink4a) overexpression in cancer: a tumor suppressor gene associated with senescence and high-grade tumors.

Romagosa C, Simonetti S, López-Vicente L, Mazo A, Lleonart ME, Castellvi J, Ramon y Cajal S.

Oncogene. 2011 May 5;30(18):2087-97. doi: 10.1038/onc.2010.614. Epub 2011 Feb 7. Review.

PMID:
21297668
4.

The regulation of INK4/ARF in cancer and aging.

Kim WY, Sharpless NE.

Cell. 2006 Oct 20;127(2):265-75. Review.

5.

Regulatory mechanisms of tumor suppressor P16(INK4A) and their relevance to cancer.

Li J, Poi MJ, Tsai MD.

Biochemistry. 2011 Jun 28;50(25):5566-82. doi: 10.1021/bi200642e. Epub 2011 Jun 6. Review.

6.

The meaning of p16(ink4a) expression in tumors: functional significance, clinical associations and future developments.

Witkiewicz AK, Knudsen KE, Dicker AP, Knudsen ES.

Cell Cycle. 2011 Aug 1;10(15):2497-503. Epub 2011 Aug 1. Review.

7.

Parsing Ink4a/Arf: "pure" p16-null mice.

Sherr CJ.

Cell. 2001 Sep 7;106(5):531-4. Review. No abstract available.

8.

Senescence in Health and Disease.

He S, Sharpless NE.

Cell. 2017 Jun 1;169(6):1000-1011. doi: 10.1016/j.cell.2017.05.015. Review.

PMID:
28575665
9.

Defining the toxicology of aging.

Sorrentino JA, Sanoff HK, Sharpless NE.

Trends Mol Med. 2014 Jul;20(7):375-84. doi: 10.1016/j.molmed.2014.04.004. Epub 2014 May 28. Review.

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