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Items: 15

1.

Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.

Williams JT, Ingram SL, Henderson G, Chavkin C, von Zastrow M, Schulz S, Koch T, Evans CJ, Christie MJ.

Pharmacol Rev. 2013 Jan 15;65(1):223-54. doi: 10.1124/pr.112.005942. Print 2013 Jan. Review.

2.

Mechanisms of rapid opioid receptor desensitization, resensitization and tolerance in brain neurons.

Dang VC, Christie MJ.

Br J Pharmacol. 2012 Mar;165(6):1704-1716. doi: 10.1111/j.1476-5381.2011.01482.x. Review.

3.

Direct association of Mu-opioid and NMDA glutamate receptors supports their cross-regulation: molecular implications for opioid tolerance.

Garzón J, Rodríguez-Muñoz M, Sánchez-Blázquez P.

Curr Drug Abuse Rev. 2012 Sep;5(3):199-226. Review.

PMID:
22920535
4.

The role of mu opioid receptor desensitization and endocytosis in morphine tolerance and dependence.

Martini L, Whistler JL.

Curr Opin Neurobiol. 2007 Oct;17(5):556-64. Epub 2007 Dec 18. Review.

PMID:
18068348
5.

The mechanism of μ-opioid receptor (MOR)-TRPV1 crosstalk in TRPV1 activation involves morphine anti-nociception, tolerance and dependence.

Bao Y, Gao Y, Yang L, Kong X, Yu J, Hou W, Hua B.

Channels (Austin). 2015;9(5):235-43. doi: 10.1080/19336950.2015.1069450. Epub 2015 Jul 15. Review.

6.

Functional selectivity at the μ-opioid receptor: implications for understanding opioid analgesia and tolerance.

Raehal KM, Schmid CL, Groer CE, Bohn LM.

Pharmacol Rev. 2011 Dec;63(4):1001-19. doi: 10.1124/pr.111.004598. Epub 2011 Aug 26. Review.

7.

Role of receptor internalization in opioid tolerance and dependence.

Koch T, Höllt V.

Pharmacol Ther. 2008 Feb;117(2):199-206. Epub 2007 Nov 17. Review.

PMID:
18076994
8.

Do pharmacological approaches that prevent opioid tolerance target different elements in the same regulatory machinery?

Garzón J, Rodríguez-Muñoz M, Sánchez-Blázquez P.

Curr Drug Abuse Rev. 2008 Jun;1(2):222-38. Review.

PMID:
19630721
9.
10.

Tracking the opioid receptors on the way of desensitization.

Marie N, Aguila B, Allouche S.

Cell Signal. 2006 Nov;18(11):1815-33. Epub 2006 Apr 15. Review.

PMID:
16750901
11.

Examining the role of mu opioid receptor endocytosis in the beneficial and side-effects of prolonged opioid use: from a symposium on new concepts in mu-opioid pharmacology.

Whistler JL.

Drug Alcohol Depend. 2012 Mar 1;121(3):189-204. doi: 10.1016/j.drugalcdep.2011.10.031. Epub 2012 Jan 9. Review.

12.

Effector antagonism by the regulators of G protein signalling (RGS) proteins causes desensitization of mu-opioid receptors in the CNS.

Garzón J, Rodríguez-Muñoz M, de la Torre-Madrid E, Sánchez-Blázquez P.

Psychopharmacology (Berl). 2005 Jun;180(1):1-11. Epub 2005 Apr 14. Review.

PMID:
15830230
13.

[Development of opioid tolerance -- molecular mechanisms and clinical consequences].

Freye E, Latasch L.

Anasthesiol Intensivmed Notfallmed Schmerzther. 2003 Jan;38(1):14-26. Review. German.

PMID:
12522725
14.

μ-Opioid receptor 6-transmembrane isoform: A potential therapeutic target for new effective opioids.

Convertino M, Samoshkin A, Gauthier J, Gold MS, Maixner W, Dokholyan NV, Diatchenko L.

Prog Neuropsychopharmacol Biol Psychiatry. 2015 Oct 1;62:61-7. doi: 10.1016/j.pnpbp.2014.11.009. Epub 2014 Dec 6. Review.

15.

The µ opioid receptor and ligands acting at the µ opioid receptor, as therapeutics and potential therapeutics.

Spetea M, Asim MF, Wolber G, Schmidhammer H.

Curr Pharm Des. 2013;19(42):7415-34. Review.

PMID:
23448479

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