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Items: 1 to 20 of 34

1.

The Keap1-Nrf2 system in cancers: stress response and anabolic metabolism.

Mitsuishi Y, Motohashi H, Yamamoto M.

Front Oncol. 2012 Dec 26;2:200. doi: 10.3389/fonc.2012.00200. eCollection 2012.

2.

Review of molecular mechanisms involved in the activation of the Nrf2-ARE signaling pathway by chemopreventive agents.

Giudice A, Arra C, Turco MC.

Methods Mol Biol. 2010;647:37-74. doi: 10.1007/978-1-60761-738-9_3. Review.

PMID:
20694660
3.

The Keap1-Nrf2 pathway: promising therapeutic target to counteract ROS-mediated damage in cancers and neurodegenerative diseases.

Deshmukh P, Unni S, Krishnappa G, Padmanabhan B.

Biophys Rev. 2017 Feb;9(1):41-56. doi: 10.1007/s12551-016-0244-4. Epub 2016 Dec 6. Review.

4.

Role of the Nrf2 signaling system in health and disease.

Hybertson BM, Gao B.

Clin Genet. 2014 Nov;86(5):447-52. doi: 10.1111/cge.12474. Epub 2014 Sep 16. Review.

PMID:
25099075
5.

Nrf2 as a master redox switch in turning on the cellular signaling involved in the induction of cytoprotective genes by some chemopreventive phytochemicals.

Surh YJ, Kundu JK, Na HK.

Planta Med. 2008 Oct;74(13):1526-39. doi: 10.1055/s-0028-1088302. Epub 2008 Oct 20. Review.

PMID:
18937164
6.

Nrf2/ARE regulated antioxidant gene expression in endothelial and smooth muscle cells in oxidative stress: implications for atherosclerosis and preeclampsia.

Mann GE, Niehueser-Saran J, Watson A, Gao L, Ishii T, de Winter P, Siow RC.

Sheng Li Xue Bao. 2007 Apr 25;59(2):117-27. Review.

8.

NRF2 and KEAP1 mutations: permanent activation of an adaptive response in cancer.

Hayes JD, McMahon M.

Trends Biochem Sci. 2009 Apr;34(4):176-88. doi: 10.1016/j.tibs.2008.12.008. Epub 2009 Mar 25. Review.

PMID:
19321346
9.

Nrf2 as a novel molecular target for chemoprevention.

Lee JS, Surh YJ.

Cancer Lett. 2005 Jun 28;224(2):171-84. Epub 2004 Nov 11. Review.

PMID:
15914268
10.

The Keap1-Nrf2-ARE Pathway As a Potential Preventive and Therapeutic Target: An Update.

Lu MC, Ji JA, Jiang ZY, You QD.

Med Res Rev. 2016 Sep;36(5):924-63. doi: 10.1002/med.21396. Epub 2016 May 18. Review.

PMID:
27192495
11.

Contradictory roles of Nrf2/Keap1 signaling pathway in cancer prevention/promotion and chemoresistance.

Jeddi F, Soozangar N, Sadeghi MR, Somi MH, Samadi N.

DNA Repair (Amst). 2017 Jun;54:13-21. doi: 10.1016/j.dnarep.2017.03.008. Epub 2017 Apr 3. Review.

PMID:
28415030
12.

Nrf2-ARE stress response mechanism: a control point in oxidative stress-mediated dysfunctions and chronic inflammatory diseases.

Singh S, Vrishni S, Singh BK, Rahman I, Kakkar P.

Free Radic Res. 2010 Nov;44(11):1267-88. doi: 10.3109/10715762.2010.507670. Review.

PMID:
20815789
13.

Nrf2 as a target for cancer chemoprevention.

Yu X, Kensler T.

Mutat Res. 2005 Dec 11;591(1-2):93-102. Epub 2005 Jul 28. Review.

PMID:
16054659
14.

The Nrf2 system as a potential target for the development of indirect antioxidants.

Jung KA, Kwak MK.

Molecules. 2010 Oct 20;15(10):7266-91. doi: 10.3390/molecules15107266. Review.

15.

Targeting nrf2 signaling to combat chemoresistance.

No JH, Kim YB, Song YS.

J Cancer Prev. 2014 Jun;19(2):111-7. doi: 10.15430/JCP.2014.19.2.111. Review.

16.

Roles nrf2 plays in myeloid cells and related disorders.

Kobayashi E, Suzuki T, Yamamoto M.

Oxid Med Cell Longev. 2013;2013:529219. doi: 10.1155/2013/529219. Epub 2013 Jun 2. Review.

17.

Multiple regulations of Keap1/Nrf2 system by dietary phytochemicals.

Qin S, Hou DX.

Mol Nutr Food Res. 2016 Aug;60(8):1731-55. doi: 10.1002/mnfr.201501017. Epub 2016 Jun 1. Review.

PMID:
27523917
18.

Emerging functional cross-talk between the Keap1-Nrf2 system and mitochondria.

Itoh K, Ye P, Matsumiya T, Tanji K, Ozaki T.

J Clin Biochem Nutr. 2015 Mar;56(2):91-7. doi: 10.3164/jcbn.14-134. Epub 2015 Mar 1. Review.

19.

An overview of chemical inhibitors of the Nrf2-ARE signaling pathway and their potential applications in cancer therapy.

Zhu J, Wang H, Chen F, Fu J, Xu Y, Hou Y, Kou HH, Zhai C, Nelson MB, Zhang Q, Andersen ME, Pi J.

Free Radic Biol Med. 2016 Oct;99:544-556. doi: 10.1016/j.freeradbiomed.2016.09.010. Epub 2016 Sep 12. Review.

PMID:
27634172
20.

Epigenetic regulation of redox signaling in diabetic retinopathy: Role of Nrf2.

Kowluru RA, Mishra M.

Free Radic Biol Med. 2017 Feb;103:155-164. doi: 10.1016/j.freeradbiomed.2016.12.030. Epub 2016 Dec 22. Review.

PMID:
28012783

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