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Items: 1 to 20 of 39

1.

A molecular mechanism for direct sirtuin activation by resveratrol.

Gertz M, Nguyen GT, Fischer F, Suenkel B, Schlicker C, Fränzel B, Tomaschewski J, Aladini F, Becker C, Wolters D, Steegborn C.

PLoS One. 2012;7(11):e49761. doi: 10.1371/journal.pone.0049761. Epub 2012 Nov 21.

2.

Sirtuin activators.

Alcaín FJ, Villalba JM.

Expert Opin Ther Pat. 2009 Apr;19(4):403-14. doi: 10.1517/13543770902762893. Review.

PMID:
19441923
3.

Function and regulation of the mitochondrial sirtuin isoform Sirt5 in Mammalia.

Gertz M, Steegborn C.

Biochim Biophys Acta. 2010 Aug;1804(8):1658-65. doi: 10.1016/j.bbapap.2009.09.011. Epub 2009 Sep 18. Review.

PMID:
19766741
4.

Sirtuins and renal diseases: relationship with aging and diabetic nephropathy.

Kitada M, Kume S, Takeda-Watanabe A, Kanasaki K, Koya D.

Clin Sci (Lond). 2013 Feb;124(3):153-64. doi: 10.1042/CS20120190. Review.

5.

Caloric restriction, resveratrol and melatonin: Role of SIRT1 and implications for aging and related-diseases.

Ramis MR, Esteban S, Miralles A, Tan DX, Reiter RJ.

Mech Ageing Dev. 2015 Mar;146-148:28-41. doi: 10.1016/j.mad.2015.03.008. Epub 2015 Mar 27. Review.

PMID:
25824609
6.

Sirtuin 1 and sirtuin 3: physiological modulators of metabolism.

Nogueiras R, Habegger KM, Chaudhary N, Finan B, Banks AS, Dietrich MO, Horvath TL, Sinclair DA, Pfluger PT, Tschöp MH.

Physiol Rev. 2012 Jul;92(3):1479-514. doi: 10.1152/physrev.00022.2011. Review.

7.

Sirtuins: novel targets for metabolic disease in drug development.

Jiang WJ.

Biochem Biophys Res Commun. 2008 Aug 29;373(3):341-4. doi: 10.1016/j.bbrc.2008.06.048. Epub 2008 Jun 23. Review.

PMID:
18577374
8.

Are sirtuins viable targets for improving healthspan and lifespan?

Baur JA, Ungvari Z, Minor RK, Le Couteur DG, de Cabo R.

Nat Rev Drug Discov. 2012 Jun 1;11(6):443-61. doi: 10.1038/nrd3738. Review.

9.

Sirtuin activators and inhibitors.

Villalba JM, Alcaín FJ.

Biofactors. 2012 Sep-Oct;38(5):349-59. doi: 10.1002/biof.1032. Epub 2012 Jun 25. Review.

10.

Resveratrol--a boon for treating Alzheimer's disease?

Anekonda TS.

Brain Res Rev. 2006 Sep;52(2):316-26. Review.

PMID:
16766037
11.

Resveratrol: a relevant pharmacological approach for the treatment of metabolic syndrome?

Beaudeux JL, Nivet-Antoine V, Giral P.

Curr Opin Clin Nutr Metab Care. 2010 Nov;13(6):729-36. doi: 10.1097/MCO.0b013e32833ef291. Review.

PMID:
20823772
12.

A patent review of sirtuin activators: an update.

Villalba JM, de Cabo R, Alcain FJ.

Expert Opin Ther Pat. 2012 Apr;22(4):355-67. doi: 10.1517/13543776.2012.669374. Epub 2012 Mar 9. Review.

PMID:
22475539
13.

Role of sirtuins in ischemia-reperfusion injury.

Pantazi E, Zaouali MA, Bejaoui M, Folch-Puy E, Ben Abdennebi H, Roselló-Catafau J.

World J Gastroenterol. 2013;19(43):7594-602. doi: 10.3748/wjg.v19.i43.7594. Review.

14.

The Sir 2 family of protein deacetylases.

Denu JM.

Curr Opin Chem Biol. 2005 Oct;9(5):431-40. Review.

PMID:
16122969
15.

Advances in characterization of human sirtuin isoforms: chemistries, targets and therapeutic applications.

Cen Y, Youn DY, Sauve AA.

Curr Med Chem. 2011;18(13):1919-35. Review.

PMID:
21517779
16.

Mechanism-based modulator discovery for sirtuin-catalyzed deacetylation reaction.

Zheng W.

Mini Rev Med Chem. 2013 Jan;13(1):132-54. Review.

PMID:
22876953
17.

Sirtuin regulation in calorie restriction.

Qiu X, Brown KV, Moran Y, Chen D.

Biochim Biophys Acta. 2010 Aug;1804(8):1576-83. doi: 10.1016/j.bbapap.2009.09.015. Epub 2009 Sep 24. Review.

PMID:
19782772
18.

SIRT3 regulates mitochondrial protein acetylation and intermediary metabolism.

Hirschey MD, Shimazu T, Huang JY, Schwer B, Verdin E.

Cold Spring Harb Symp Quant Biol. 2011;76:267-77. doi: 10.1101/sqb.2011.76.010850. Epub 2011 Nov 23. Review.

PMID:
22114326
19.

SIRT1 and other sirtuins in metabolism.

Chang HC, Guarente L.

Trends Endocrinol Metab. 2014 Mar;25(3):138-45. doi: 10.1016/j.tem.2013.12.001. Epub 2013 Dec 30. Review.

20.

Therapeutic potential of activators and inhibitors of sirtuins.

Balcerczyk A, Pirola L.

Biofactors. 2010 Sep-Oct;36(5):383-93. doi: 10.1002/biof.112. Review.

PMID:
20848588

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