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Items: 10

1.

Alisertib (MLN8237) an investigational agent suppresses Aurora A and B activity, inhibits proliferation, promotes endo-reduplication and induces apoptosis in T-NHL cell lines supporting its importance in PTCL treatment.

Qi W, Spier C, Liu X, Agarwal A, Cooke LS, Persky DO, Chen D, Miller TP, Mahadevan D.

Leuk Res. 2013 Apr;37(4):434-9. doi: 10.1016/j.leukres.2012.10.017.

2.

MLN8237 ( alisertib ) and its role in peripheral T-cell lymphoma.

Alrifai D, Pettengell R.

Expert Opin Investig Drugs. 2014 Dec;23(12):1731-6. doi: 10.1517/13543784.2014.972501. Review.

PMID:
25323772
3.

The role of alisertib in treatment of peripheral T-cell lymphomas.

Gallop-Evans E.

Future Oncol. 2015 Sep;11(18):2515-24. doi: 10.2217/fon.15.154. Review.

PMID:
26344156
4.

Aurora-B kinase inhibitors for cancer chemotherapy.

Yeung SC, Gully C, Lee MH.

Mini Rev Med Chem. 2008 Dec;8(14):1514-25. Review.

PMID:
19075809
5.

Molecular genetics of peripheral T-cell lymphomas.

Piccaluga PP, Tabanelli V, Pileri SA.

Int J Hematol. 2014 Mar;99(3):219-26. doi: 10.1007/s12185-014-1522-1. Review.

PMID:
24481943
6.

Update on aurora kinase inhibitors in gynecologic malignancies.

Tao X, Chon HS, Fu S, Kavanagh JJ, Hu W.

Recent Pat Anticancer Drug Discov. 2008 Nov;3(3):162-77. Review.

7.

The potential role of Aurora kinase inhibitors in haematological malignancies.

Farag SS.

Br J Haematol. 2011 Dec;155(5):561-79. doi: 10.1111/j.1365-2141.2011.08898.x. Review.

8.

Aurora kinases in head and neck cancer.

Mehra R, Serebriiskii IG, Burtness B, Astsaturov I, Golemis EA.

Lancet Oncol. 2013 Sep;14(10):e425-35. doi: 10.1016/S1470-2045(13)70128-1. Review.

9.

Scientific Rationale Supporting the Clinical Development Strategy for the Investigational Aurora A Kinase Inhibitor Alisertib in Cancer.

Niu H, Manfredi M, Ecsedy JA.

Front Oncol. 2015 Aug 24;5:189. doi: 10.3389/fonc.2015.00189. Review.

10.

From empiric to mechanism-based therapy for peripheral T cell lymphoma.

Intlekofer AM, Younes A.

Int J Hematol. 2014 Mar;99(3):249-62. doi: 10.1007/s12185-014-1521-2. Review.

PMID:
24510453
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