Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 18

1.

Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome.

Jung KM, Sepers M, Henstridge CM, Lassalle O, Neuhofer D, Martin H, Ginger M, Frick A, DiPatrizio NV, Mackie K, Katona I, Piomelli D, Manzoni OJ.

Nat Commun. 2012;3:1080. doi: 10.1038/ncomms2045.

2.

Metabotropic glutamate receptors and fragile x mental retardation protein: partners in translational regulation at the synapse.

Ronesi JA, Huber KM.

Sci Signal. 2008 Feb 5;1(5):pe6. doi: 10.1126/stke.15pe6. Review.

PMID:
18272470
3.

Role for metabotropic glutamate receptor 5 (mGluR5) in the pathogenesis of fragile X syndrome.

Dölen G, Bear MF.

J Physiol. 2008 Mar 15;586(6):1503-8. doi: 10.1113/jphysiol.2008.150722. Epub 2008 Jan 17. Review.

4.

Potential therapeutic interventions for fragile X syndrome.

Levenga J, de Vrij FM, Oostra BA, Willemsen R.

Trends Mol Med. 2010 Nov;16(11):516-27. doi: 10.1016/j.molmed.2010.08.005. Epub 2010 Sep 21. Review.

5.

Mechanism-based approaches to treating fragile X.

Dölen G, Carpenter RL, Ocain TD, Bear MF.

Pharmacol Ther. 2010 Jul;127(1):78-93. doi: 10.1016/j.pharmthera.2010.02.008. Epub 2010 Mar 18. Review.

PMID:
20303363
6.

Fragile X syndrome: a preclinical review on metabotropic glutamate receptor 5 (mGluR5) antagonists and drug development.

Pop AS, Gomez-Mancilla B, Neri G, Willemsen R, Gasparini F.

Psychopharmacology (Berl). 2014 Mar;231(6):1217-26. Review.

PMID:
24232444
7.

The state of synapses in fragile X syndrome.

Pfeiffer BE, Huber KM.

Neuroscientist. 2009 Oct;15(5):549-67. doi: 10.1177/1073858409333075. Epub 2009 Mar 26. Review.

8.

BDNF in fragile X syndrome.

Castrén ML, Castrén E.

Neuropharmacology. 2014 Jan;76 Pt C:729-36. doi: 10.1016/j.neuropharm.2013.05.018. Epub 2013 May 29. Review.

PMID:
23727436
9.

Fragile X syndrome: loss of local mRNA regulation alters synaptic development and function.

Bassell GJ, Warren ST.

Neuron. 2008 Oct 23;60(2):201-14. doi: 10.1016/j.neuron.2008.10.004. Review.

10.

Fragile X syndrome: From protein function to therapy.

Bagni C, Oostra BA.

Am J Med Genet A. 2013 Nov;161A(11):2809-21. doi: 10.1002/ajmg.a.36241. Epub 2013 Sep 24. Review.

PMID:
24115651
11.

Fragile X syndrome and targeted treatment trials.

Hagerman R, Lauterborn J, Au J, Berry-Kravis E.

Results Probl Cell Differ. 2012;54:297-335. doi: 10.1007/978-3-642-21649-7_17. Review.

12.

The mGluR theory of fragile X mental retardation.

Bear MF, Huber KM, Warren ST.

Trends Neurosci. 2004 Jul;27(7):370-7. Review.

PMID:
15219735
13.

Autism, Alzheimer disease, and fragile X: APP, FMRP, and mGluR5 are molecular links.

Sokol DK, Maloney B, Long JM, Ray B, Lahiri DK.

Neurology. 2011 Apr 12;76(15):1344-52. doi: 10.1212/WNL.0b013e3182166dc7. Review.

14.

Dysregulation of group-I metabotropic glutamate (mGlu) receptor mediated signalling in disorders associated with Intellectual Disability and Autism.

D'Antoni S, Spatuzza M, Bonaccorso CM, Musumeci SA, Ciranna L, Nicoletti F, Huber KM, Catania MV.

Neurosci Biobehav Rev. 2014 Oct;46 Pt 2:228-41. doi: 10.1016/j.neubiorev.2014.02.003. Epub 2014 Feb 15. Review.

15.

The pathophysiology of fragile X (and what it teaches us about synapses).

Bhakar AL, Dölen G, Bear MF.

Annu Rev Neurosci. 2012;35:417-43. doi: 10.1146/annurev-neuro-060909-153138. Epub 2012 Apr 5. Review.

16.

Molecular mechanisms of fragile X syndrome: a twenty-year perspective.

Santoro MR, Bray SM, Warren ST.

Annu Rev Pathol. 2012;7:219-45. doi: 10.1146/annurev-pathol-011811-132457. Epub 2011 Oct 10. Review.

PMID:
22017584
17.

Group I metabotropic glutamate receptors: a role in neurodevelopmental disorders?

Catania MV, D'Antoni S, Bonaccorso CM, Aronica E, Bear MF, Nicoletti F.

Mol Neurobiol. 2007 Jun;35(3):298-307. Review.

PMID:
17917118
18.

Moving Toward Integrative, Multidimensional Research in Modern Psychiatry: Lessons Learned From Fragile X Syndrome.

Fung LK, Reiss AL.

Biol Psychiatry. 2016 Jul 15;80(2):100-111. doi: 10.1016/j.biopsych.2015.12.015. Epub 2015 Dec 18. Review.

Supplemental Content

Support Center