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Items: 4


FLT3-ITD knockin impairs hematopoietic stem cell quiescence/homeostasis, leading to myeloproliferative neoplasm.

Chu SH, Heiser D, Li L, Kaplan I, Collector M, Huso D, Sharkis SJ, Civin C, Small D.

Cell Stem Cell. 2012 Sep 7;11(3):346-58. doi: 10.1016/j.stem.2012.05.027.


Allogeneic stem cell transplantation and targeted therapy for FLT3/ITD+ acute myeloid leukemia: an update.

Hu B, Vikas P, Mohty M, Savani BN.

Expert Rev Hematol. 2014 Apr;7(2):301-15. doi: 10.1586/17474086.2014.857596. Epub 2013 Dec 6. Review.


Role of SIRT1 in the growth and regulation of normal hematopoietic and leukemia stem cells.

Li L, Bhatia R.

Curr Opin Hematol. 2015 Jul;22(4):324-9. doi: 10.1097/MOH.0000000000000152. Review.


Leukemia and hematopoietic stem cells: balancing proliferation and quiescence.

Jude CD, Gaudet JJ, Speck NA, Ernst P.

Cell Cycle. 2008 Mar 1;7(5):586-91. Epub 2008 Jan 1. Review.

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