Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 14

1.

Oncogenic Kras maintains pancreatic tumors through regulation of anabolic glucose metabolism.

Ying H, Kimmelman AC, Lyssiotis CA, Hua S, Chu GC, Fletcher-Sananikone E, Locasale JW, Son J, Zhang H, Coloff JL, Yan H, Wang W, Chen S, Viale A, Zheng H, Paik JH, Lim C, Guimaraes AR, Martin ES, Chang J, Hezel AF, Perry SR, Hu J, Gan B, Xiao Y, Asara JM, Weissleder R, Wang YA, Chin L, Cantley LC, DePinho RA.

Cell. 2012 Apr 27;149(3):656-70. doi: 10.1016/j.cell.2012.01.058.

2.

Critical role of oncogenic KRAS in pancreatic cancer (Review).

Liu J, Ji S, Liang C, Qin Y, Jin K, Liang D, Xu W, Shi S, Zhang B, Liu L, Liu C, Xu J, Ni Q, Yu X.

Mol Med Rep. 2016 Jun;13(6):4943-9. doi: 10.3892/mmr.2016.5196. Epub 2016 Apr 27. Review.

PMID:
27121414
3.

KRAS: feeding pancreatic cancer proliferation.

Bryant KL, Mancias JD, Kimmelman AC, Der CJ.

Trends Biochem Sci. 2014 Feb;39(2):91-100. doi: 10.1016/j.tibs.2013.12.004. Epub 2014 Jan 2. Review.

4.

Targeting metabolic reprogramming in KRAS-driven cancers.

Kawada K, Toda K, Sakai Y.

Int J Clin Oncol. 2017 Aug;22(4):651-659. doi: 10.1007/s10147-017-1156-4. Epub 2017 Jun 24. Review.

PMID:
28647837
5.

Critical role of hnRNP A1 in activating KRAS transcription in pancreatic cancer cells: A molecular mechanism involving G4 DNA.

Cogoi S, Rapozzi V, Cauci S, Xodo LE.

Biochim Biophys Acta. 2017 May;1861(5 Pt B):1389-1398. doi: 10.1016/j.bbagen.2016.11.031. Epub 2016 Nov 22. Review.

PMID:
27888145
6.

The Significance of Ras Activity in Pancreatic Cancer Initiation.

Logsdon CD, Lu W.

Int J Biol Sci. 2016 Jan 28;12(3):338-46. doi: 10.7150/ijbs.15020. eCollection 2016. Review.

7.

Overview on how oncogenic Kras promotes pancreatic carcinogenesis by inducing low intracellular ROS levels.

Kong B, Qia C, Erkan M, Kleeff J, Michalski CW.

Front Physiol. 2013 Sep 12;4:246. doi: 10.3389/fphys.2013.00246. Review.

8.

The Key Role of Calmodulin in KRAS-Driven Adenocarcinomas.

Nussinov R, Muratcioglu S, Tsai CJ, Jang H, Gursoy A, Keskin O.

Mol Cancer Res. 2015 Sep;13(9):1265-73. doi: 10.1158/1541-7786.MCR-15-0165. Epub 2015 Jun 17. Review.

9.

Metabolic Dependencies in RAS-Driven Cancers.

Kimmelman AC.

Clin Cancer Res. 2015 Apr 15;21(8):1828-34. doi: 10.1158/1078-0432.CCR-14-2425. Review.

10.

Pancreatitis promotes oncogenic Kras(G12D)-induced pancreatic transformation through activation of Nupr1.

Grasso D, Garcia MN, Hamidi T, Cano C, Calvo E, Lomberk G, Urrutia R, Iovanna JL.

Mol Cell Oncol. 2014 Jul 28;1(1):e29913. doi: 10.4161/mco.29913. eCollection 2014. Review.

11.

KRAS, YAP, and obesity in pancreatic cancer: A signaling network with multiple loops.

Eibl G, Rozengurt E.

Semin Cancer Biol. 2017 Oct 24. pii: S1044-579X(17)30223-7. doi: 10.1016/j.semcancer.2017.10.007. [Epub ahead of print] Review.

PMID:
29079305
12.

The complex landscape of pancreatic cancer metabolism.

Sousa CM, Kimmelman AC.

Carcinogenesis. 2014 Jul;35(7):1441-50. doi: 10.1093/carcin/bgu097. Epub 2014 Apr 17. Review.

13.

KRAS Mutant Pancreatic Cancer: No Lone Path to an Effective Treatment.

Zeitouni D, Pylayeva-Gupta Y, Der CJ, Bryant KL.

Cancers (Basel). 2016 Apr 18;8(4). pii: E45. doi: 10.3390/cancers8040045. Review.

14.

Leveraging Mechanisms Governing Pancreatic Tumorigenesis To Reduce Pancreatic Cancer Mortality.

Donahue TR, Dawson DW.

Trends Endocrinol Metab. 2016 Nov;27(11):770-781. doi: 10.1016/j.tem.2016.06.009. Epub 2016 Jul 25. Review.

Supplemental Content

Support Center