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Items: 11

1.

Mdm2's dilemma: to degrade or to translate p53?

Hamard PJ, Manfredi JJ.

Cancer Cell. 2012 Jan 17;21(1):3-5. doi: 10.1016/j.ccr.2011.12.018.

2.

Functions of the MDM2 oncoprotein.

Freedman DA, Wu L, Levine AJ.

Cell Mol Life Sci. 1999 Jan;55(1):96-107. Review.

PMID:
10065155
3.

ATM-mediated phosphorylations inhibit Mdmx/Mdm2 stabilization by HAUSP in favor of p53 activation.

Meulmeester E, Pereg Y, Shiloh Y, Jochemsen AG.

Cell Cycle. 2005 Sep;4(9):1166-70. Epub 2005 Sep 29. Review.

PMID:
16082221
4.

Unlocking the Mdm2-p53 loop: ubiquitin is the key.

Clegg HV, Itahana K, Zhang Y.

Cell Cycle. 2008 Feb 1;7(3):287-92. Epub 2007 Nov 25. Review.

PMID:
18235222
5.

Mdm2 links genotoxic stress and metabolism to p53.

Wang Z, Li B.

Protein Cell. 2010 Dec;1(12):1063-72. doi: 10.1007/s13238-010-0140-9. Epub 2011 Jan 8. Review.

6.

MDM2 Increases Drug Resistance in Cancer Cells by Inducing EMT Independent of p53.

Sun W, Tang L.

Curr Med Chem. 2016;23(40):4529-4539. Review.

PMID:
27686656
7.

Escape, or Vanish: Control the Fate of p53 through MDM2-Mediated Ubiquitination.

Wei J, Yang Y, Lu M, Xu L, Liu F, Yuan Z, Bao Q, Jiang Z, Xu X, Guo X, Zhang X, You Q, Sun H.

Anticancer Agents Med Chem. 2015;16(2):174-89. Review.

PMID:
26343143
8.

Targeting MDM2-p53 interaction for cancer therapy: are we there yet?

Nag S, Zhang X, Srivenugopal KS, Wang MH, Wang W, Zhang R.

Curr Med Chem. 2014;21(5):553-74. Review.

PMID:
24180275
9.

The RP-Mdm2-p53 pathway and tumorigenesis.

Miliani de Marval PL, Zhang Y.

Oncotarget. 2011 Mar;2(3):234-8. Review.

10.

MDM2's social network.

FĂ„hraeus R, Olivares-Illana V.

Oncogene. 2014 Aug 28;33(35):4365-76. doi: 10.1038/onc.2013.410. Epub 2013 Oct 7. Review.

PMID:
24096477
11.

A new twist in the feedback loop: stress-activated MDM2 destabilization is required for p53 activation.

Stommel JM, Wahl GM.

Cell Cycle. 2005 Mar;4(3):411-7. Epub 2005 Mar 2. Review.

PMID:
15684615

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