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Items: 1 to 20 of 21

1.

Recent progress in understanding molecular mechanisms of cartilage degeneration during osteoarthritis.

Wang M, Shen J, Jin H, Im HJ, Sandy J, Chen D.

Ann N Y Acad Sci. 2011 Dec;1240:61-9. doi: 10.1111/j.1749-6632.2011.06258.x. Review.

2.

Indian Hedgehog, a critical modulator in osteoarthritis, could be a potential therapeutic target for attenuating cartilage degeneration disease.

Zhou J, Wei X, Wei L.

Connect Tissue Res. 2014 Aug;55(4):257-61. doi: 10.3109/03008207.2014.925885. Epub 2014 Jun 13. Review.

PMID:
24844414
3.

TGF-b signaling in cartilage homeostasis and osteoarthritis.

Finnson KW, Chi Y, Bou-Gharios G, Leask A, Philip A.

Front Biosci (Schol Ed). 2012 Jan 1;4:251-68. Review.

PMID:
22202058
4.

Roles of TGF-beta 1 signaling in the development of osteoarthritis.

Fang J, Xu L, Li Y, Zhao Z.

Histol Histopathol. 2016 Nov;31(11):1161-7. doi: 10.14670/HH-11-779. Epub 2016 May 11. Review.

PMID:
27164863
5.

Wnt-beta-catenin signaling in the pathogenesis of osteoarthritis.

Corr M.

Nat Clin Pract Rheumatol. 2008 Oct;4(10):550-6. doi: 10.1038/ncprheum0904. Review.

PMID:
18820702
6.

Cartilage development and degeneration: a Wnt Wnt situation.

Staines KA, Macrae VE, Farquharson C.

Cell Biochem Funct. 2012 Dec;30(8):633-42. doi: 10.1002/cbf.2852. Epub 2012 Jun 19. Review.

PMID:
22714865
7.

Insights on biology and pathology of HIF-1α/-2α, TGFβ/BMP, Wnt/β-catenin, and NF-κB pathways in osteoarthritis.

Wu L, Huang X, Li L, Huang H, Xu R, Luyten W.

Curr Pharm Des. 2012;18(22):3293-312. Review.

PMID:
22646092
8.

Genetically modified chondrocytes expressing TGF-β1: a revolutionary treatment for articular cartilage damage?

Elmallah RK, Cherian JJ, Jauregui JJ, Pierce TP, Beaver WB, Mont MA.

Expert Opin Biol Ther. 2015 Mar;15(3):455-64. doi: 10.1517/14712598.2015.1009886. Epub 2015 Feb 3. Review.

PMID:
25645308
9.
10.

The current progress in understanding the molecular functions and mechanisms of visfatin in osteoarthritis.

Liao L, Chen Y, Wang W.

J Bone Miner Metab. 2016 Sep;34(5):485-90. doi: 10.1007/s00774-016-0743-1. Epub 2016 Mar 11. Review.

PMID:
26969394
11.

HIF-2α as a possible therapeutic target of osteoarthritis.

Saito T, Kawaguchi H.

Osteoarthritis Cartilage. 2010 Dec;18(12):1552-6. doi: 10.1016/j.joca.2010.10.006. Epub 2010 Oct 13. Review.

12.

TGF-β signal transduction pathways and osteoarthritis.

Zhai G, Doré J, Rahman P.

Rheumatol Int. 2015 Aug;35(8):1283-92. doi: 10.1007/s00296-015-3251-z. Epub 2015 Mar 15. Review.

PMID:
25773660
13.

Molecular players at the intersection of obesity and osteoarthritis.

Bonet ML, Granados N, Palou A.

Curr Drug Targets. 2011 Dec;12(14):2103-28. Review.

PMID:
22023406
14.

Interleukin-1 and transforming growth factor-beta 1 as crucial factors in osteoarthritic cartilage metabolism.

Pujol JP, Chadjichristos C, Legendre F, Bauge C, Beauchef G, Andriamanalijaona R, Galera P, Boumediene K.

Connect Tissue Res. 2008;49(3):293-7. doi: 10.1080/03008200802148355. Review.

PMID:
18661363
15.

Analysing the role of endogenous matrix molecules in the development of osteoarthritis.

Sofat N.

Int J Exp Pathol. 2009 Oct;90(5):463-79. doi: 10.1111/j.1365-2613.2009.00676.x. Review.

16.

To seek shelter from the WNT in osteoarthritis? WNT-signaling as a target for osteoarthritis therapy.

Blom AB, van Lent PL, van der Kraan PM, van den Berg WB.

Curr Drug Targets. 2010 May;11(5):620-9. Review.

PMID:
20199388
17.

Molecular and biophysical mechanisms regulating hypertrophic differentiation in chondrocytes and mesenchymal stem cells.

Studer D, Millan C, Öztürk E, Maniura-Weber K, Zenobi-Wong M.

Eur Cell Mater. 2012 Jul 24;24:118-35; discussion 135. Review.

18.

Extracellular matrix and pathogenic mechanisms in osteoarthritis.

Hardingham T.

Curr Rheumatol Rep. 2008 Jan;10(1):30-6. Review.

PMID:
18457609
19.

The role of progenitor cells in osteoarthritis development and progression.

Labusca L, Mashayekhi K.

Curr Stem Cell Res Ther. 2015;10(2):90-8. Review.

PMID:
24975620
20.

Molecular mechanisms of cartilage destruction: mechanics, inflammatory mediators, and aging collide.

Loeser RF.

Arthritis Rheum. 2006 May;54(5):1357-60. Review. No abstract available.

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