Format

Send to

Choose Destination

Links from PubMed

See comment in PubMed Commons below
J Am Coll Cardiol. 2011 Nov 1;58(19):1970-4. doi: 10.1016/j.jacc.2011.08.012.

Relationship between sodium intake and sleep apnea in patients with heart failure.

Author information

  • 1Sleep Research Laboratory of the Toronto Rehabilitation Institute, University of Toronto, Toronto, Ontario, Canada.

Abstract

OBJECTIVES:

The purpose of this study was to test the hypothesis that severity of sleep apnea (SA), assessed by frequency of apneas and hypopneas per hour of sleep (apnea-hypopnea index [AHI]), is related to sodium intake in patients with heart failure (HF).

BACKGROUND:

Dependent edema and overnight rostral fluid shift from the legs correlate with the AHI in patients with HF in whom excessive sodium intake can cause fluid retention.

METHODS:

Sodium intake was estimated by food recordings in 54 HF patients who underwent overnight polysomnography.

RESULTS:

Thirty-one of the 54 patients had SA, and their mean sodium intake was higher than that in those without SA (3.0 ± 1.2 g vs. 1.9 ± 0.8 g, p < 0.001). There was a significant correlation between the AHI and sodium intake (r = 0.522, p < 0.001). Multivariate analysis showed that the significant independent correlates of the AHI were sodium intake, male sex, and serum creatinine level.

CONCLUSIONS:

These findings suggest that in patients with HF, sodium intake plays a role in the pathogenesis of SA.

Copyright © 2011 American College of Cardiology Foundation. Published by Elsevier Inc. All rights reserved.

[PubMed - indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Write to the Help Desk