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Items: 1 to 20 of 38

1.

Integration of dosimetry, exposure, and high-throughput screening data in chemical toxicity assessment.

Wetmore BA, Wambaugh JF, Ferguson SS, Sochaski MA, Rotroff DM, Freeman K, Clewell HJ 3rd, Dix DJ, Andersen ME, Houck KA, Allen B, Judson RS, Singh R, Kavlock RJ, Richard AM, Thomas RS.

Toxicol Sci. 2012 Jan;125(1):157-74. doi: 10.1093/toxsci/kfr254. Epub 2011 Sep 26.

2.

Quantitative in vitro-to-in vivo extrapolation in a high-throughput environment.

Wetmore BA.

Toxicology. 2015 Jun 5;332:94-101. doi: 10.1016/j.tox.2014.05.012. Epub 2014 Jun 5. Review.

PMID:
24907440
3.

Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.

EFSA GMO Panel Working Group on Animal Feeding Trials.

Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. doi: 10.1016/j.fct.2008.02.008. Epub 2008 Feb 13. Review.

PMID:
18328408
4.

Quantitative in vitro to in vivo extrapolation of cell-based toxicity assay results.

Yoon M, Campbell JL, Andersen ME, Clewell HJ.

Crit Rev Toxicol. 2012 Sep;42(8):633-52. doi: 10.3109/10408444.2012.692115. Epub 2012 Jun 6. Review.

PMID:
22667820
5.

Total allowable concentrations of monomeric inorganic aluminum and hydrated aluminum silicates in drinking water.

Willhite CC, Ball GL, McLellan CJ.

Crit Rev Toxicol. 2012 May;42(5):358-442. doi: 10.3109/10408444.2012.674101. Review.

PMID:
22512666
6.

Predictive models and computational toxicology.

Knudsen T, Martin M, Chandler K, Kleinstreuer N, Judson R, Sipes N.

Methods Mol Biol. 2013;947:343-74. doi: 10.1007/978-1-62703-131-8_26. Review.

PMID:
23138916
7.

Determination of a site-specific reference dose for methylmercury for fish-eating populations.

Shipp AM, Gentry PR, Lawrence G, Van Landingham C, Covington T, Clewell HJ, Gribben K, Crump K.

Toxicol Ind Health. 2000 Nov;16(9-10):335-438. Review.

PMID:
11762928
8.

Screening chemicals for thyroid-disrupting activity: A critical comparison of mammalian and amphibian models.

Pickford DB.

Crit Rev Toxicol. 2010 Nov;40(10):845-92. doi: 10.3109/10408444.2010.494250. Review.

PMID:
20684730
9.
10.

Relevance of in vitro neurotoxicity testing for regulatory requirements: challenges to be considered.

Bal-Price AK, Hogberg HT, Buzanska L, Coecke S.

Neurotoxicol Teratol. 2010 Jan-Feb;32(1):36-41. doi: 10.1016/j.ntt.2008.12.003. Epub 2008 Dec 24. Review.

PMID:
19150401
13.

Toxicity assessment strategies, data requirements, and risk assessment approaches to derive health based guidance values for non-relevant metabolites of plant protection products.

Dekant W, Melching-Kollmuss S, Kalberlah F.

Regul Toxicol Pharmacol. 2010 Mar;56(2):135-42. doi: 10.1016/j.yrtph.2009.10.003. Epub 2009 Oct 31. Review.

PMID:
19883711
14.

Kinetic determinants of hepatic clearance: plasma protein binding and hepatic uptake.

Baker M, Parton T.

Xenobiotica. 2007 Oct-Nov;37(10-11):1110-34. Review.

PMID:
17968739
15.

Threshold of toxicological concern for chemical substances present in the diet: a practical tool for assessing the need for toxicity testing.

Kroes R, Galli C, Munro I, Schilter B, Tran L, Walker R, W├╝rtzen G.

Food Chem Toxicol. 2000 Feb-Mar;38(2-3):255-312. Review.

PMID:
10717364
16.

Endocrine disrupters--testing strategies to assess human hazard.

Baker VA.

Toxicol In Vitro. 2001 Aug-Oct;15(4-5):413-9. Review.

PMID:
11566572
17.

Dose metric considerations in in vitro assays to improve quantitative in vitro-in vivo dose extrapolations.

Groothuis FA, Heringa MB, Nicol B, Hermens JL, Blaauboer BJ, Kramer NI.

Toxicology. 2015 Jun 5;332:30-40. doi: 10.1016/j.tox.2013.08.012. Epub 2013 Aug 23. Review.

PMID:
23978460
18.

In vitro and modelling approaches to risk assessment from the U.S. Environmental Protection Agency ToxCast programme.

Judson R, Houck K, Martin M, Knudsen T, Thomas RS, Sipes N, Shah I, Wambaugh J, Crofton K.

Basic Clin Pharmacol Toxicol. 2014 Jul;115(1):69-76. doi: 10.1111/bcpt.12239. Epub 2014 Apr 22. Review.

19.

Organotypic liver culture models: meeting current challenges in toxicity testing.

LeCluyse EL, Witek RP, Andersen ME, Powers MJ.

Crit Rev Toxicol. 2012 Jul;42(6):501-48. doi: 10.3109/10408444.2012.682115. Epub 2012 May 15. Review.

20.

Chemical Safety for Sustainability (CSS): human in vivo biomonitoring data for complementing results from in vitro toxicology--a commentary.

Pleil JD, Williams MA, Sobus JR.

Toxicol Lett. 2012 Dec 17;215(3):201-7. doi: 10.1016/j.toxlet.2012.10.011. Epub 2012 Oct 30. Review.

PMID:
23116968
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