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Items: 9


A new disease-specific machine learning approach for the prediction of cancer-causing missense variants.

Capriotti E, Altman RB.

Genomics. 2011 Oct;98(4):310-7. doi: 10.1016/j.ygeno.2011.06.010. Epub 2011 Jul 7.


Computational prediction of the effects of non-synonymous single nucleotide polymorphisms in human DNA repair genes.

Nakken S, Alseth I, Rognes T.

Neuroscience. 2007 Apr 14;145(4):1273-9. Epub 2006 Oct 19. Review.


Prediction of deleterious nonsynonymous single-nucleotide polymorphism for human diseases.

Wu J, Jiang R.

ScientificWorldJournal. 2013;2013:675851. doi: 10.1155/2013/675851. Epub 2013 Jan 30. Review.


Identifying driver mutations from sequencing data of heterogeneous tumors in the era of personalized genome sequencing.

Zhang J, Liu J, Sun J, Chen C, Foltz G, Lin B.

Brief Bioinform. 2014 Mar;15(2):244-55. doi: 10.1093/bib/bbt042. Epub 2013 Jul 1. Review.


News from the protein mutability landscape.

Hecht M, Bromberg Y, Rost B.

J Mol Biol. 2013 Nov 1;425(21):3937-48. doi: 10.1016/j.jmb.2013.07.028. Epub 2013 Jul 26. Review. Erratum in: J Mol Biol. 2014 Jan 23;426(2):501.


Towards precision medicine: advances in computational approaches for the analysis of human variants.

Peterson TA, Doughty E, Kann MG.

J Mol Biol. 2013 Nov 1;425(21):4047-63. doi: 10.1016/j.jmb.2013.08.008. Epub 2013 Aug 17. Review.


Single nucleotide variations: biological impact and theoretical interpretation.

Katsonis P, Koire A, Wilson SJ, Hsu TK, Lua RC, Wilkins AD, Lichtarge O.

Protein Sci. 2014 Dec;23(12):1650-66. doi: 10.1002/pro.2552. Epub 2014 Oct 20. Review.


Molecular mechanisms of disease-causing missense mutations.

Stefl S, Nishi H, Petukh M, Panchenko AR, Alexov E.

J Mol Biol. 2013 Nov 1;425(21):3919-36. doi: 10.1016/j.jmb.2013.07.014. Epub 2013 Jul 16. Review.


Computational and experimental approaches to reveal the effects of single nucleotide polymorphisms with respect to disease diagnostics.

Kucukkal TG, Yang Y, Chapman SC, Cao W, Alexov E.

Int J Mol Sci. 2014 May 30;15(6):9670-717. doi: 10.3390/ijms15069670. Review.

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