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Items: 12

1.

Quantification of repolarization reserve to understand interpatient variability in the response to proarrhythmic drugs: a computational analysis.

Sarkar AX, Sobie EA.

Heart Rhythm. 2011 Nov;8(11):1749-55. doi: 10.1016/j.hrthm.2011.05.023. Epub 2011 Jun 7.

2.

In silico risk assessment for drug-induction of cardiac arrhythmia.

Suzuki S, Murakami S, Tsujimae K, Findlay I, Kurachi Y.

Prog Biophys Mol Biol. 2008 Sep;98(1):52-60. doi: 10.1016/j.pbiomolbio.2008.05.003. Epub 2008 May 29. Review.

PMID:
18635251
3.

Pharmacological modulation of I(Ks): potential for antiarrhythmic therapy.

Salataa JJ, Selnickb HG, Lynch JJ Jr.

Curr Med Chem. 2004 Jan;11(1):29-44. Review.

PMID:
14754424
4.

Theoretical possibilities for the development of novel antiarrhythmic drugs.

Varró A, Biliczki P, Iost N, Virág L, Hála O, Kovács P, Mátyus P, Papp JG.

Curr Med Chem. 2004 Jan;11(1):1-11. Review.

PMID:
14754422
5.

Enhanced repolarization capacity: new potential antiarrhythmic strategy based on HERG channel activation.

Szabó G, Farkas V, Grunnet M, Mohácsi A, Nánási PP.

Curr Med Chem. 2011;18(24):3607-21. Review.

PMID:
21774764
6.

[HERG K+ channel, the target of anti-arrhythmias drugs].

Guan FY, Yang SJ.

Yao Xue Xue Bao. 2007 Jul;42(7):687-91. Review. Chinese.

PMID:
17882949
7.
8.

Profile of I(Ks) during the action potential questions the therapeutic value of I(Ks) blockade.

Bányász T, Koncz R, Fülöp L, Szentandrássy N, Magyar J, Nánási PP.

Curr Med Chem. 2004 Jan;11(1):45-60. Review.

PMID:
14754425
9.
10.

Mechanism of Proarrhythmic Effects of Potassium Channel Blockers.

Skibsbye L, Ravens U.

Card Electrophysiol Clin. 2016 Jun;8(2):395-410. doi: 10.1016/j.ccep.2016.02.004. Epub 2016 Mar 24. Review.

PMID:
27261830
11.

Exploiting mathematical models to illuminate electrophysiological variability between individuals.

Sarkar AX, Christini DJ, Sobie EA.

J Physiol. 2012 Jun 1;590(11):2555-67. doi: 10.1113/jphysiol.2011.223313. Epub 2012 Apr 10. Review.

12.

Top-down, Bottom-up and Middle-out Strategies for Drug Cardiac Safety Assessment via Modeling and Simulations.

Tylutki Z, Polak S, Wiśniowska B.

Curr Pharmacol Rep. 2016;2:171-177. Epub 2016 Apr 5. Review.

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