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Items: 17

1.

Exploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome--clozapine-induced agranulocytosis as a case study.

Yang L, Wang K, Chen J, Jegga AG, Luo H, Shi L, Wan C, Guo X, Qin S, He G, Feng G, He L.

PLoS Comput Biol. 2011 Mar;7(3):e1002016. doi: 10.1371/journal.pcbi.1002016. Epub 2011 Mar 31.

2.

[Clozapine-induced agranulocytosis: genetic risk factors and an immunologic explanatory model].

G├╝zelcan Y, Scholte WF.

Tijdschr Psychiatr. 2006;48(4):295-302. Review. Dutch.

3.

Clozapine-induced agranulocytosis and its genetic determinants.

Opgen-Rhein C, Dettling M.

Pharmacogenomics. 2008 Aug;9(8):1101-11. doi: 10.2217/14622416.9.8.1101. Review.

PMID:
18681784
4.
5.

HSP70-2 9.0 kb variant is in linkage disequilibrium with the HLA-B and DRB1* alleles associated with clozapine-induced agranulocytosis.

Corzo D, Yunis JJ, Yunis EJ, Howard A, Lieberman JA.

J Clin Psychiatry. 1994 Sep;55 Suppl B:149-52. Review.

PMID:
7961560
6.

Possible role of free radical formation in drug-induced agranulocytosis.

Mason RP, Fischer V.

Drug Saf. 1992;7 Suppl 1:45-50. Review.

PMID:
1503677
7.

Clinical profile of clozapine: adverse reactions and agranulocytosis.

Lieberman JA, Safferman AZ.

Psychiatr Q. 1992 Spring;63(1):51-70. Review.

PMID:
1438605
8.

Clozapine: the commitment to patient safety.

Alphs LD, Anand R.

J Clin Psychiatry. 1999;60 Suppl 12:39-42. Review.

9.

Mechanisms of clozapine-induced agranulocytosis.

Gerson SL, Meltzer H.

Drug Saf. 1992;7 Suppl 1:17-25. Review.

PMID:
1503673
10.

Drug-induced agranulocytosis: review of possible mechanisms, and prospects for clozapine studies.

Claas FH.

Psychopharmacology (Berl). 1989;99 Suppl:S113-7. Review.

PMID:
2682726
11.

Reducing clozapine-related morbidity and mortality: 5 years of experience with the Clozaril National Registry.

Honigfeld G, Arellano F, Sethi J, Bianchini A, Schein J.

J Clin Psychiatry. 1998;59 Suppl 3:3-7. Review.

12.

Clozapine-associated agranulocytosis: risk and aetiology.

Krupp P, Barnes P.

Br J Psychiatry Suppl. 1992 May;(17):38-40. Review.

PMID:
1418887
13.

Reactive metabolites and agranulocytosis.

Uetrecht JP.

Eur J Haematol Suppl. 1996;60:83-8. Review.

PMID:
8987247
14.

Chemical-protein interactome and its application in off-target identification.

Yang L, Wang KJ, Wang LS, Jegga AG, Qin SY, He G, Chen J, Xiao Y, He L.

Interdiscip Sci. 2011 Mar;3(1):22-30. doi: 10.1007/s12539-011-0051-8. Epub 2011 Mar 3. Review.

PMID:
21369884
15.

Current understanding of the mechanisms of idiosyncratic drug-induced agranulocytosis.

Johnston A, Uetrecht J.

Expert Opin Drug Metab Toxicol. 2015 Feb;11(2):243-57. doi: 10.1517/17425255.2015.985649. Epub 2014 Nov 26. Review.

PMID:
25424130
16.

Clozapine: balancing safety with superior antipsychotic efficacy.

Meltzer HY.

Clin Schizophr Relat Psychoses. 2012 Oct;6(3):134-44. Review.

PMID:
23006238
17.

More than 25 years of genetic studies of clozapine-induced agranulocytosis.

de With SAJ, Pulit SL, Staal WG, Kahn RS, Ophoff RA.

Pharmacogenomics J. 2017 Apr 18. doi: 10.1038/tpj.2017.6. [Epub ahead of print] Review.

PMID:
28418011

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