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Items: 1 to 20 of 49

1.

Probe Reports from the NIH Molecular Libraries Program [Internet].

Bethesda (MD): National Center for Biotechnology Information (US); 2010-.

2.

Open access high throughput drug discovery in the public domain: a Mount Everest in the making.

Roy A, McDonald PR, Sittampalam S, Chaguturu R.

Curr Pharm Biotechnol. 2010 Nov;11(7):764-78. Review.

3.

Integration of small-molecule discovery in academic biomedical research.

Ohlmeyer M, Zhou MM.

Mt Sinai J Med. 2010 Jul-Aug;77(4):350-7. doi: 10.1002/msj.20197. Review.

4.

An Overview of the Challenges in Designing, Integrating, and Delivering BARD: A Public Chemical-Biology Resource and Query Portal for Multiple Organizations, Locations, and Disciplines.

de Souza A, Bittker JA, Lahr DL, Brudz S, Chatwin S, Oprea TI, Waller A, Yang JJ, Southall N, Guha R, Schürer SC, Vempati UD, Southern MR, Dawson ES, Clemons PA, Chung TD.

J Biomol Screen. 2014 Jun;19(5):614-27. doi: 10.1177/1087057113517139. Epub 2014 Jan 17. Review.

5.

High-Throughput and High-Content Screening for Huntington’s Disease Therapeutics.

Varma H, Lo DC, Stockwell BR.

In: Lo DC, Hughes RE, editors. Neurobiology of Huntington's Disease: Applications to Drug Discovery. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 5.

6.

Novel trends in high-throughput screening.

Mayr LM, Bojanic D.

Curr Opin Pharmacol. 2009 Oct;9(5):580-8. doi: 10.1016/j.coph.2009.08.004. Epub 2009 Sep 21. Review.

PMID:
19775937
7.

Small-Molecule Screens: A Gateway to Cancer Therapeutic Agents with Case Studies of Food and Drug Administration-Approved Drugs.

Coussens NP, Braisted JC, Peryea T, Sittampalam GS, Simeonov A, Hall MD.

Pharmacol Rev. 2017 Oct;69(4):479-496. doi: 10.1124/pr.117.013755. Review.

8.

High impact technologies for natural products screening.

Koehn FE.

Prog Drug Res. 2008;65:175, 177-210. Review.

PMID:
18084916
9.

PubChem as a public resource for drug discovery.

Li Q, Cheng T, Wang Y, Bryant SH.

Drug Discov Today. 2010 Dec;15(23-24):1052-7. doi: 10.1016/j.drudis.2010.10.003. Epub 2010 Oct 21. Review.

10.

Advancing Biological Understanding and Therapeutics Discovery with Small-Molecule Probes.

Schreiber SL, Kotz JD, Li M, Aubé J, Austin CP, Reed JC, Rosen H, White EL, Sklar LA, Lindsley CW, Alexander BR, Bittker JA, Clemons PA, de Souza A, Foley MA, Palmer M, Shamji AF, Wawer MJ, McManus O, Wu M, Zou B, Yu H, Golden JE, Schoenen FJ, Simeonov A, Jadhav A, Jackson MR, Pinkerton AB, Chung TD, Griffin PR, Cravatt BF, Hodder PS, Roush WR, Roberts E, Chung DH, Jonsson CB, Noah JW, Severson WE, Ananthan S, Edwards B, Oprea TI, Conn PJ, Hopkins CR, Wood MR, Stauffer SR, Emmitte KA; NIH Molecular Libraries Project Team.

Cell. 2015 Jun 4;161(6):1252-65. doi: 10.1016/j.cell.2015.05.023. Review.

11.

Charting, navigating, and populating natural product chemical space for drug discovery.

Lachance H, Wetzel S, Kumar K, Waldmann H.

J Med Chem. 2012 Jul 12;55(13):5989-6001. doi: 10.1021/jm300288g. Epub 2012 May 11. Review.

PMID:
22537178
12.

The role of HTS in drug discovery at the University of Michigan.

Larsen MJ, Larsen SD, Fribley A, Grembecka J, Homan K, Mapp A, Haak A, Nikolovska-Coleska Z, Stuckey JA, Sun D, Sherman DH.

Comb Chem High Throughput Screen. 2014 Mar;17(3):210-30. Review.

13.

[Aiming for zero blindness].

Nakazawa T.

Nippon Ganka Gakkai Zasshi. 2015 Mar;119(3):168-93; discussion 194. Review. Japanese.

PMID:
25854109
14.

Current practices in generation of small molecule new leads.

Goodnow RA Jr.

J Cell Biochem Suppl. 2001;Suppl 37:13-21. Review.

PMID:
11842423
15.

Selenium- and tellurium-containing fluorescent molecular probes for the detection of biologically important analytes.

Manjare ST, Kim Y, Churchill DG.

Acc Chem Res. 2014 Oct 21;47(10):2985-98. doi: 10.1021/ar500187v. Epub 2014 Sep 23. Review.

PMID:
25248146
16.

Campaign to identify novel modulators of the Retinoic acid receptor-related Orphan Receptors (ROR).

Kumar N, Solt LA, Conkright J, Wang Y, Istrate MA, Busby SA, Garcia-Ordonez RD, Nuhant P, Burris T, Mercer BA, Hodder P, Roush WR, Rosen H, Griffin PR.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2009 Jan 3 [updated 2011 Mar 11].

17.

Early Probe and Drug Discovery in Academia: A Minireview.

Roy A.

High Throughput. 2018 Feb 9;7(1). pii: E4. doi: 10.3390/ht7010004. Review.

19.

Identification of Small Molecule Inhibitors of Wee1 Degradation and Mitotic Entry.

Simanski S, Madoux F, Rahaim RJ, Chase P, Schurer S, Cameron M, Mercer BA, Hodder P, Roush WR, Ayad NG.

Probe Reports from the NIH Molecular Libraries Program [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2010-.
2010 Sep 1 [updated 2013 Mar 22].

20.

High throughput screening in duchenne muscular dystrophy: from drug discovery to functional genomics.

Gintjee TJ, Magh AS, Bertoni C.

Biology (Basel). 2014 Nov 14;3(4):752-80. doi: 10.3390/biology3040752. Review.

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