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Biomed Opt Express. 2011 Jan 31;2(3):440-51. doi: 10.1364/BOE.2.000440.

Optical Tomography in weakly scattering media in the presence of highly scattering inclusions.

Abstract

We consider the problem of optical tomographic imaging in a weakly scattering medium in the presence of highly scattering inclusions. The approach is based on the assumption that the transport coefficient of the scattering media differs by an order of magnitude for weakly and highly scattering regions. This situation is common for optical imaging of live objects such an embryo. We present an approximation to the radiative transfer equation, which can be applied to this type of scattering case. Our approach was verified by reconstruction of two optical parameters from numerically simulated datasets.

KEYWORDS:

(170.0170) Medical optics and biotechnology; (170.3010) Image reconstruction techniques; (290.0290) Scattering; (290.7050) Turbid media

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