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Items: 6

1.

KSR1 is a functional protein kinase capable of serine autophosphorylation and direct phosphorylation of MEK1.

Goettel JA, Liang D, Hilliard VC, Edelblum KL, Broadus MR, Gould KL, Hanks SK, Polk DB.

Exp Cell Res. 2011 Feb 15;317(4):452-63. doi: 10.1016/j.yexcr.2010.11.018. Epub 2010 Dec 7.

2.

Inflammatory bowel disease reveals the kinase activity of KSR1.

Kolesnick R, Xing HR.

J Clin Invest. 2004 Nov;114(9):1233-7. Review.

3.

MEK1/2 dual-specificity protein kinases: structure and regulation.

Roskoski R Jr.

Biochem Biophys Res Commun. 2012 Jan 6;417(1):5-10. doi: 10.1016/j.bbrc.2011.11.145. Epub 2011 Dec 8. Review.

PMID:
22177953
4.

The dual function of KSR1: a pseudokinase and beyond.

Zhang H, Koo CY, Stebbing J, Giamas G.

Biochem Soc Trans. 2013 Aug;41(4):1078-82. doi: 10.1042/BST20130042. Review.

PMID:
23863182
5.

MEK1/2 inhibitors in the treatment of gynecologic malignancies.

Miller CR, Oliver KE, Farley JH.

Gynecol Oncol. 2014 Apr;133(1):128-37. doi: 10.1016/j.ygyno.2014.01.008. Epub 2014 Jan 14. Review.

PMID:
24434059
6.

Coordinating ERK signaling via the molecular scaffold Kinase Suppressor of Ras.

Frodyma D, Neilsen B, Costanzo-Garvey D, Fisher K, Lewis R.

F1000Res. 2017 Aug 31;6:1621. doi: 10.12688/f1000research.11895.1. eCollection 2017. Review.

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