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Items: 13


BID, BIM, and PUMA are essential for activation of the BAX- and BAK-dependent cell death program.

Ren D, Tu HC, Kim H, Wang GX, Bean GR, Takeuchi O, Jeffers JR, Zambetti GP, Hsieh JJ, Cheng EH.

Science. 2010 Dec 3;330(6009):1390-3. doi: 10.1126/science.1190217.


Mitochondrial membrane permeabilisation by Bax/Bak.

Degli Esposti M, Dive C.

Biochem Biophys Res Commun. 2003 May 9;304(3):455-61. Review.


Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.

Korsmeyer SJ, Wei MC, Saito M, Weiler S, Oh KJ, Schlesinger PH.

Cell Death Differ. 2000 Dec;7(12):1166-73. Review.


Control of mitochondrial permeability by Bcl-2 family members.

Sharpe JC, Arnoult D, Youle RJ.

Biochim Biophys Acta. 2004 Mar 1;1644(2-3):107-13. Review.


MAC and Bcl-2 family proteins conspire in a deadly plot.

Dejean LM, Ryu SY, Martinez-Caballero S, Teijido O, Peixoto PM, Kinnally KW.

Biochim Biophys Acta. 2010 Jun-Jul;1797(6-7):1231-8. doi: 10.1016/j.bbabio.2010.01.007. Epub 2010 Jan 18. Review.


Building blocks of the apoptotic pore: how Bax and Bak are activated and oligomerize during apoptosis.

Westphal D, Kluck RM, Dewson G.

Cell Death Differ. 2014 Feb;21(2):196-205. doi: 10.1038/cdd.2013.139. Epub 2013 Oct 25. Review.


Regulated necrotic cell death: the passive aggressive side of Bax and Bak.

Karch J, Molkentin JD.

Circ Res. 2015 May 22;116(11):1800-9. doi: 10.1161/CIRCRESAHA.116.305421. Review.


Molecular biology of Bax and Bak activation and action.

Westphal D, Dewson G, Czabotar PE, Kluck RM.

Biochim Biophys Acta. 2011 Apr;1813(4):521-31. doi: 10.1016/j.bbamcr.2010.12.019. Epub 2010 Dec 30. Review.


Importance of proapoptotic protein PUMA in cell radioresistance.

Vávrová J, Rezáčová M.

Folia Biol (Praha). 2014;60(2):53-6. Review.


BCL-2 family proteins as regulators of mitochondria metabolism.

Gross A.

Biochim Biophys Acta. 2016 Aug;1857(8):1243-6. doi: 10.1016/j.bbabio.2016.01.017. Epub 2016 Jan 29. Review.


In vivo contributions of BH3-only proteins to neuronal death following seizures, ischemia, and traumatic brain injury.

Engel T, Plesnila N, Prehn JH, Henshall DC.

J Cereb Blood Flow Metab. 2011 May;31(5):1196-210. doi: 10.1038/jcbfm.2011.26. Epub 2011 Mar 2. Review.


The pleiotropic effects of heterologous Bax expression in yeast.

Khoury CM, Greenwood MT.

Biochim Biophys Acta. 2008 Jul;1783(7):1449-65. doi: 10.1016/j.bbamcr.2007.12.013. Epub 2008 Jan 16. Review.


BIM, PUMA, and the achilles' heel of oncogene addiction.

Roulston A, Muller WJ, Shore GC.

Sci Signal. 2013 Mar 26;6(268):pe12. doi: 10.1126/scisignal.2004113. Review.


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