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Items: 1 to 20 of 25

1.

Glucose and weight control in mice with a designed ghrelin O-acyltransferase inhibitor.

Barnett BP, Hwang Y, Taylor MS, Kirchner H, Pfluger PT, Bernard V, Lin YY, Bowers EM, Mukherjee C, Song WJ, Longo PA, Leahy DJ, Hussain MA, Tschöp MH, Boeke JD, Cole PA.

Science. 2010 Dec 17;330(6011):1689-92. doi: 10.1126/science.1196154. Epub 2010 Nov 18.

2.

Ghrelin O-acyltransferase assays and inhibition.

Taylor MS, Hwang Y, Hsiao PY, Boeke JD, Cole PA.

Methods Enzymol. 2012;514:205-28. doi: 10.1016/B978-0-12-381272-8.00013-1. Review.

3.

Ghrelin O-acyltransferase (GOAT) and energy metabolism.

Li Z, Mulholland M, Zhang W.

Sci China Life Sci. 2016 Mar;59(3):281-91. doi: 10.1007/s11427-015-4973-6. Epub 2016 Jan 6. Review.

PMID:
26732975
4.

Ghrelin acylation and metabolic control.

Al Massadi O, Tschöp MH, Tong J.

Peptides. 2011 Nov;32(11):2301-8. doi: 10.1016/j.peptides.2011.08.020. Epub 2011 Aug 27. Review.

PMID:
21893140
5.

Ghrelin and glucose homeostasis.

Delhanty PJ, van der Lely AJ.

Peptides. 2011 Nov;32(11):2309-18. doi: 10.1016/j.peptides.2011.03.001. Epub 2011 Mar 21. Review.

PMID:
21396419
6.

GOAT: the master switch for the ghrelin system?

Romero A, Kirchner H, Heppner K, Pfluger PT, Tschöp MH, Nogueiras R.

Eur J Endocrinol. 2010 Jul;163(1):1-8. doi: 10.1530/EJE-10-0099. Epub 2010 Apr 26. Review.

7.

Physiological role of ghrelin as revealed by the ghrelin and GOAT knockout mice.

Kang K, Zmuda E, Sleeman MW.

Peptides. 2011 Nov;32(11):2236-41. doi: 10.1016/j.peptides.2011.04.028. Epub 2011 May 10. Review.

PMID:
21600256
8.

Ghrelin function in insulin release and glucose metabolism.

Dezaki K.

Endocr Dev. 2013;25:135-43. doi: 10.1159/000346064. Epub 2013 Apr 25. Review.

PMID:
23652399
9.

The ghrelin O-acyltransferase-ghrelin system: a novel regulator of glucose metabolism.

Heppner KM, Tong J, Kirchner H, Nass R, Tschöp MH.

Curr Opin Endocrinol Diabetes Obes. 2011 Feb;18(1):50-5. doi: 10.1097/MED.0b013e328341e1d3. Review.

PMID:
21150588
10.

Ghrelin is a physiological regulator of insulin release in pancreatic islets and glucose homeostasis.

Dezaki K, Sone H, Yada T.

Pharmacol Ther. 2008 May;118(2):239-49. doi: 10.1016/j.pharmthera.2008.02.008. Epub 2008 Mar 10. Review.

PMID:
18433874
11.

Ghrelin O-acyltransferase (GOAT), a specific enzyme that modifies ghrelin with a medium-chain fatty acid.

Kojima M, Hamamoto A, Sato T.

J Biochem. 2016 Oct;160(4):189-194. Epub 2016 Aug 3. Review.

PMID:
27489223
12.

Products of the ghrelin gene, the pancreatic β-cell and the adipocyte.

Granata R, Ghigo E.

Endocr Dev. 2013;25:144-56. doi: 10.1159/000346306. Epub 2013 Apr 25. Review.

PMID:
23652400
13.

Membrane bound O-acyltransferases and their inhibitors.

Masumoto N, Lanyon-Hogg T, Rodgers UR, Konitsiotis AD, Magee AI, Tate EW.

Biochem Soc Trans. 2015 Apr;43(2):246-52. doi: 10.1042/BST20150018. Review.

PMID:
25849925
14.

Neuroendocrine and metabolic activities of ghrelin gene products.

Baragli A, Lanfranco F, Allasia S, Granata R, Ghigo E.

Peptides. 2011 Nov;32(11):2323-32. doi: 10.1016/j.peptides.2011.10.024. Epub 2011 Oct 30. Review.

PMID:
22056513
15.

Revisiting the metabolism and physiological functions of caprylic acid (C8:0) with special focus on ghrelin octanoylation.

Lemarié F, Beauchamp E, Legrand P, Rioux V.

Biochimie. 2016 Jan;120:40-8. doi: 10.1016/j.biochi.2015.08.002. Epub 2015 Aug 4. Review.

PMID:
26253695
16.

Ghrelin's second life: from appetite stimulator to glucose regulator.

Verhulst PJ, Depoortere I.

World J Gastroenterol. 2012 Jul 7;18(25):3183-95. doi: 10.3748/wjg.v18.i25.3183. Review.

17.

Introducing GOAT: a target for obesity and anti-diabetic drugs?

Gualillo O, Lago F, Dieguez C.

Trends Pharmacol Sci. 2008 Aug;29(8):398-401. doi: 10.1016/j.tips.2008.06.003. Epub 2008 Jul 6. Review.

PMID:
18606462
18.

Ghrelin gene products and the regulation of food intake and gut motility.

Chen CY, Asakawa A, Fujimiya M, Lee SD, Inui A.

Pharmacol Rev. 2009 Dec;61(4):430-81. doi: 10.1124/pr.109.001958. Review.

19.

Mechanisms in endocrinology: regulation of glucose metabolism by the ghrelin system: multiple players and multiple actions.

Heppner KM, Tong J.

Eur J Endocrinol. 2014 Jul;171(1):R21-32. doi: 10.1530/EJE-14-0183. Epub 2014 Apr 8. Review.

20.

The ghrelin/GOAT/GHS-R system and energy metabolism.

Lim CT, Kola B, Korbonits M.

Rev Endocr Metab Disord. 2011 Sep;12(3):173-86. doi: 10.1007/s11154-011-9169-1. Review.

PMID:
21340583

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