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Items: 11


Exposure to hexavalent chromium resulted in significantly higher tissue chromium burden compared with trivalent chromium following similar oral doses to male F344/N rats and female B6C3F1 mice.

Collins BJ, Stout MD, Levine KE, Kissling GE, Melnick RL, Fennell TR, Walden R, Abdo K, Pritchard JB, Fernando RA, Burka LT, Hooth MJ.

Toxicol Sci. 2010 Dec;118(2):368-79. doi: 10.1093/toxsci/kfq263. Epub 2010 Sep 15.


Is hexavalent chromium carcinogenic via ingestion? A weight-of-evidence review.

Proctor DM, Otani JM, Finley BL, Paustenbach DJ, Bland JA, Speizer N, Sargent EV.

J Toxicol Environ Health A. 2002 May 24;65(10):701-46. Review.


Chromium in drinking water: sources, metabolism, and cancer risks.

Zhitkovich A.

Chem Res Toxicol. 2011 Oct 17;24(10):1617-29. doi: 10.1021/tx200251t. Epub 2011 Jul 28. Review.


Oral Chromium Exposure and Toxicity.

Sun H, Brocato J, Costa M.

Curr Environ Health Rep. 2015 Sep;2(3):295-303. doi: 10.1007/s40572-015-0054-z. Review.


Assessment of the mode of action for hexavalent chromium-induced lung cancer following inhalation exposures.

Proctor DM, Suh M, Campleman SL, Thompson CM.

Toxicology. 2014 Nov 5;325:160-79. doi: 10.1016/j.tox.2014.08.009. Epub 2014 Aug 28. Review.


Lack of genotoxic effects in hematopoietic and gastrointestinal cells of mice receiving chromium(VI) with the drinking water.

De Flora S, D'Agostini F, Balansky R, Micale R, Baluce B, Izzotti A.

Mutat Res. 2008 Jul-Aug;659(1-2):60-7. Epub 2007 Nov 19. Review.


Assessment of the mode of action underlying development of rodent small intestinal tumors following oral exposure to hexavalent chromium and relevance to humans.

Thompson CM, Proctor DM, Suh M, Haws LC, Kirman CR, Harris MA.

Crit Rev Toxicol. 2013 Mar;43(3):244-74. doi: 10.3109/10408444.2013.768596. Review.


Chromium in the environment: an evaluation of exposure of the UK general population and possible adverse health effects.

Rowbotham AL, Levy LS, Shuker LK.

J Toxicol Environ Health B Crit Rev. 2000 Jul-Sep;3(3):145-78. Review.


Application of the U.S. EPA mode of action Framework for purposes of guiding future research: a case study involving the oral carcinogenicity of hexavalent chromium.

Thompson CM, Haws LC, Harris MA, Gatto NM, Proctor DM.

Toxicol Sci. 2011 Jan;119(1):20-40. doi: 10.1093/toxsci/kfq320. Epub 2010 Oct 14. Review.


Chromium and genomic stability.

Wise SS, Wise JP Sr.

Mutat Res. 2012 May 1;733(1-2):78-82. doi: 10.1016/j.mrfmmm.2011.12.002. Epub 2011 Dec 13. Review.


Toxicological Profile for Chromium.

Wilbur S, Abadin H, Fay M, Yu D, Tencza B, Ingerman L, Klotzbach J, James S.

Atlanta (GA): Agency for Toxic Substances and Disease Registry (US); 2012 Sep.

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