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Items: 1 to 20 of 51

1.

Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism.

ter Haar E, Koth CM, Abdul-Manan N, Swenson L, Coll JT, Lippke JA, Lepre CA, Garcia-Guzman M, Moore JM.

Structure. 2010 Sep 8;18(9):1083-93. doi: 10.1016/j.str.2010.05.014.

2.

CGRP receptor antagonism and migraine therapy.

Edvinsson L, Warfvinge K.

Curr Protein Pept Sci. 2013 Aug;14(5):386-92. Review.

PMID:
23745702
3.

Ligand binding and activation of the CGRP receptor.

Conner AC, Simms J, Barwell J, Wheatley M, Poyner DR.

Biochem Soc Trans. 2007 Aug;35(Pt 4):729-32. Review.

PMID:
17635135
4.

The tortuous road to an ideal CGRP function blocker for the treatment of migraine.

Davis CD, Xu C.

Curr Top Med Chem. 2008;8(16):1468-79. Review.

PMID:
18991732
5.

The activation of the CGRP receptor.

Barwell J, Wheatley M, Conner AC, Taddese B, Vohra S, Reynolds CA, Poyner DR.

Biochem Soc Trans. 2013 Feb 1;41(1):180-4. doi: 10.1042/BST20120251. Review.

PMID:
23356280
6.

Ectodomain structures of the CGRP and AM receptors.

Kusano S, Yokoyama S.

Curr Protein Pept Sci. 2013 Aug;14(5):375-85. Review.

PMID:
23745701
7.

The role of the extracellular loops of the CGRP receptor, a family B GPCR.

Barwell J, Woolley MJ, Wheatley M, Conner AC, Poyner DR.

Biochem Soc Trans. 2012 Apr;40(2):433-7. doi: 10.1042/BST20110726. Review.

PMID:
22435826
8.

CGRP receptors in the control of pain and inflammation.

Benemei S, Nicoletti P, Capone JG, Geppetti P.

Curr Opin Pharmacol. 2009 Feb;9(1):9-14. doi: 10.1016/j.coph.2008.12.007. Epub 2009 Jan 20. Review.

PMID:
19157980
9.

CGRP antagonists: hope for a new era in acute migraine treatment.

Schelstraete C, Paemeleire K.

Acta Neurol Belg. 2009 Dec;109(4):252-61. Review.

PMID:
20120204
10.

The role of CGRP in the pathophysiology of migraine and efficacy of CGRP receptor antagonists as acute antimigraine drugs.

Villalón CM, Olesen J.

Pharmacol Ther. 2009 Dec;124(3):309-23. doi: 10.1016/j.pharmthera.2009.09.003. Epub 2009 Sep 29. Review.

PMID:
19796656
11.

Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine.

Moore EL, Salvatore CA.

Br J Pharmacol. 2012 May;166(1):66-78. doi: 10.1111/j.1476-5381.2011.01633.x. Review.

12.

Heterodimers and family-B GPCRs: RAMPs, CGRP and adrenomedullin.

Conner AC, Simms J, Hay DL, Mahmoud K, Howitt SG, Wheatley M, Poyner DR.

Biochem Soc Trans. 2004 Nov;32(Pt 5):843-6. Review.

PMID:
15494030
13.

Calcitonin gene-related peptide receptor antagonists for migraine.

Fischer MJ.

Expert Opin Investig Drugs. 2010 Jul;19(7):815-23. doi: 10.1517/13543784.2010.490829. Review.

PMID:
20482328
14.

Calcitonin gene-related peptide receptor antagonists for the treatment of migraine: a patent review.

Paone DV, Staas DD.

Expert Opin Ther Pat. 2009 Dec;19(12):1675-713. doi: 10.1517/13543770903359822. Review.

PMID:
19939188
15.

Interaction of calcitonin-gene-related peptide with its receptors.

Conner AC, Hay DL, Howitt SG, Kilk K, Langel U, Wheatley M, Smith DM, Poyner DR.

Biochem Soc Trans. 2002 Aug;30(4):451-5. Review.

PMID:
12196113
16.

Functions of third extracellular loop and helix 8 of Family B GPCRs complexed with RAMPs and characteristics of their receptor trafficking.

Kuwasako K, Hay DL, Nagata S, Murakami M, Kitamura K, Kato J.

Curr Protein Pept Sci. 2013 Aug;14(5):416-28. Review.

PMID:
23745705
17.

Calcitonin gene-related peptide receptor antagonists for the treatment of migraine.

Williams TM, Burgey CS, Salvatore CA.

Prog Med Chem. 2009;47:1-35. doi: 10.1016/S0079-6468(08)00201-4. Review. No abstract available.

PMID:
19328288
18.

CGRP antagonists: unravelling the role of CGRP in migraine.

Doods H, Arndt K, Rudolf K, Just S.

Trends Pharmacol Sci. 2007 Nov;28(11):580-7. Epub 2007 Oct 25. Review.

PMID:
17963849
19.

CGRP receptor antagonists: an expanding drug class for acute migraine?

Negro A, Lionetto L, Simmaco M, Martelletti P.

Expert Opin Investig Drugs. 2012 Jun;21(6):807-18. doi: 10.1517/13543784.2012.681044. Epub 2012 Apr 19. Review.

PMID:
22512641
20.

[CGRP antagonists: novel concept for treatment of migraine].

Nieber K.

Med Monatsschr Pharm. 2009 May;32(5):182-5. Review. German.

PMID:
19469188

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