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Items: 1 to 20 of 95

1.

Integration of small-molecule discovery in academic biomedical research.

Ohlmeyer M, Zhou MM.

Mt Sinai J Med. 2010 Jul-Aug;77(4):350-7. doi: 10.1002/msj.20197. Review.

2.

The role of HTS in drug discovery at the University of Michigan.

Larsen MJ, Larsen SD, Fribley A, Grembecka J, Homan K, Mapp A, Haak A, Nikolovska-Coleska Z, Stuckey JA, Sun D, Sherman DH.

Comb Chem High Throughput Screen. 2014 Mar;17(3):210-30. Review.

3.

Open access high throughput drug discovery in the public domain: a Mount Everest in the making.

Roy A, McDonald PR, Sittampalam S, Chaguturu R.

Curr Pharm Biotechnol. 2010 Nov;11(7):764-78. Review.

4.

[Development of antituberculous drugs: current status and future prospects].

Tomioka H, Namba K.

Kekkaku. 2006 Dec;81(12):753-74. Review. Japanese.

PMID:
17240921
5.

[The discovery process in the pharmaceutical industry].

Scatton B.

J Soc Biol. 2009;203(3):249-69. doi: 10.1051/jbio:2009030. Epub 2009 Oct 16. Review. French.

PMID:
19833071
6.

Principles of early drug discovery.

Hughes JP, Rees S, Kalindjian SB, Philpott KL.

Br J Pharmacol. 2011 Mar;162(6):1239-49. doi: 10.1111/j.1476-5381.2010.01127.x. Review.

7.

The role of academic institutions in the development of drugs for rare and neglected diseases.

Coles LD, Cloyd JC.

Clin Pharmacol Ther. 2012 Aug;92(2):193-202. doi: 10.1038/clpt.2012.83. Epub 2012 Jul 4. Review.

PMID:
22760003
8.

Academic drug discovery: current status and prospects.

Everett JR.

Expert Opin Drug Discov. 2015;10(9):937-44. doi: 10.1517/17460441.2015.1059816. Epub 2015 Jun 19. Review.

PMID:
26088126
9.

High-Throughput and High-Content Screening for Huntington’s Disease Therapeutics.

Varma H, Lo DC, Stockwell BR.

In: Lo DC, Hughes RE, editors. Neurobiology of Huntington's Disease: Applications to Drug Discovery. Boca Raton (FL): CRC Press/Taylor & Francis; 2011. Chapter 5.

10.

Novel trends in high-throughput screening.

Mayr LM, Bojanic D.

Curr Opin Pharmacol. 2009 Oct;9(5):580-8. doi: 10.1016/j.coph.2009.08.004. Epub 2009 Sep 21. Review.

PMID:
19775937
11.

Alternative strategies in drug development: clinical pharmacological aspects.

Kuhlmann J.

Int J Clin Pharmacol Ther. 1999 Dec;37(12):575-83. Review.

PMID:
10599949
12.

Impact of high-throughput screening in biomedical research.

Macarron R, Banks MN, Bojanic D, Burns DJ, Cirovic DA, Garyantes T, Green DV, Hertzberg RP, Janzen WP, Paslay JW, Schopfer U, Sittampalam GS.

Nat Rev Drug Discov. 2011 Mar;10(3):188-95. doi: 10.1038/nrd3368. Review.

PMID:
21358738
13.

Integrating molecular design resources within modern drug discovery research: the Roche experience.

Stahl M, Guba W, Kansy M.

Drug Discov Today. 2006 Apr;11(7-8):326-33. Review.

PMID:
16580974
14.

No Denying It: Medicinal Chemistry Training Is in Big Trouble.

Rafferty MF.

J Med Chem. 2016 Dec 22;59(24):10859-10864. doi: 10.1021/acs.jmedchem.6b00741. Epub 2016 Oct 7. Review.

PMID:
27668824
15.

Chemical proteomics and its application to drug discovery.

Jeffery DA, Bogyo M.

Curr Opin Biotechnol. 2003 Feb;14(1):87-95. Review.

PMID:
12566007
16.

Achievements, Challenges, and Opportunities in DNA-Encoded Library Research: An Academic Point of View.

Yuen LH, Franzini RM.

Chembiochem. 2017 May 4;18(9):829-836. doi: 10.1002/cbic.201600567. Epub 2017 Jan 25. Review.

PMID:
28032411
17.

Drug discovery in academia.

Verkman AS.

Am J Physiol Cell Physiol. 2004 Mar;286(3):C465-74. Review.

18.

Fragment-based drug discovery: what has it achieved so far?

Alex AA, Flocco MM.

Curr Top Med Chem. 2007;7(16):1544-67. Review.

PMID:
17979767
19.

From Protein Structure to Small-Molecules: Recent Advances and Applications to Fragment-Based Drug Discovery.

Ferreira LG, Andricopulo AD.

Curr Top Med Chem. 2017;17(20):2260-2270. doi: 10.2174/1568026617666170224113437. Review.

PMID:
28240184
20.

Recent progress in biomolecular engineering.

Ryu DD, Nam DH.

Biotechnol Prog. 2000 Jan-Feb;16(1):2-16. Review.

PMID:
10662483

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