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Items: 1 to 20 of 58

1.

With TOR, less is more: a key role for the conserved nutrient-sensing TOR pathway in aging.

Kapahi P, Chen D, Rogers AN, Katewa SD, Li PW, Thomas EL, Kockel L.

Cell Metab. 2010 Jun 9;11(6):453-65. doi: 10.1016/j.cmet.2010.05.001. Review.

2.

Role of TOR signaling in aging and related biological processes in Drosophila melanogaster.

Katewa SD, Kapahi P.

Exp Gerontol. 2011 May;46(5):382-90. doi: 10.1016/j.exger.2010.11.036. Epub 2010 Dec 2. Review.

3.

mTOR's role in ageing: protein synthesis or autophagy?

Hands SL, Proud CG, Wyttenbach A.

Aging (Albany NY). 2009 Jul 20;1(7):586-97. Review.

4.

TOR signaling never gets old: aging, longevity and TORC1 activity.

Evans DS, Kapahi P, Hsueh WC, Kockel L.

Ageing Res Rev. 2011 Apr;10(2):225-37. doi: 10.1016/j.arr.2010.04.001. Epub 2010 Apr 10. Review.

5.

Dietary restriction and aging, 2009.

Katewa SD, Kapahi P.

Aging Cell. 2010 Apr;9(2):105-12. doi: 10.1111/j.1474-9726.2010.00552.x. Epub 2010 Jan 20. Review.

6.

Protein synthesis and the antagonistic pleiotropy hypothesis of aging.

Kapahi P.

Adv Exp Med Biol. 2010;694:30-7. Review.

PMID:
20886754
7.

mTOR regulation of autophagy.

Jung CH, Ro SH, Cao J, Otto NM, Kim DH.

FEBS Lett. 2010 Apr 2;584(7):1287-95. doi: 10.1016/j.febslet.2010.01.017. Epub 2010 Jan 18. Review.

8.

Amino acid sensing in dietary-restriction-mediated longevity: roles of signal-transducing kinases GCN2 and TOR.

Gallinetti J, Harputlugil E, Mitchell JR.

Biochem J. 2013 Jan 1;449(1):1-10. doi: 10.1042/BJ20121098. Review.

9.

Metabolic control by target of rapamycin and autophagy during ageing - a mini-review.

Markaki M, Tavernarakis N.

Gerontology. 2013;59(4):340-8. doi: 10.1159/000348599. Epub 2013 Apr 9. Review.

10.

TOR Signaling and Nutrient Sensing.

Dobrenel T, Caldana C, Hanson J, Robaglia C, Vincentz M, Veit B, Meyer C.

Annu Rev Plant Biol. 2016 Apr 29;67:261-85. doi: 10.1146/annurev-arplant-043014-114648. Epub 2016 Feb 22. Review.

PMID:
26905651
11.

The expanding TOR signaling network.

Martin DE, Hall MN.

Curr Opin Cell Biol. 2005 Apr;17(2):158-66. Review.

PMID:
15780592
12.

Functional consequences of mTOR inhibition.

Sudarsanam S, Johnson DE.

Curr Opin Drug Discov Devel. 2010 Jan;13(1):31-40. Review.

PMID:
20047144
13.

Growth control via TOR kinase signaling, an intracellular sensor of amino acid and energy availability, with crosstalk potential to proline metabolism.

Liao XH, Majithia A, Huang X, Kimmel AR.

Amino Acids. 2008 Nov;35(4):761-70. doi: 10.1007/s00726-008-0100-3. Epub 2008 Jul 24. Review.

PMID:
18651095
14.

Dietary Protein, Metabolism, and Aging.

Soultoukis GA, Partridge L.

Annu Rev Biochem. 2016 Jun 2;85:5-34. doi: 10.1146/annurev-biochem-060815-014422. Epub 2016 Apr 29. Review.

PMID:
27145842
15.

Mammalian target of rapamycin signaling and autophagy: roles in lymphangioleiomyomatosis therapy.

Yu J, Parkhitko AA, Henske EP.

Proc Am Thorac Soc. 2010 Feb;7(1):48-53. doi: 10.1513/pats.200909-104JS. Review.

16.

TOR pathway: linking nutrient sensing to life span.

Kapahi P, Zid B.

Sci Aging Knowledge Environ. 2004 Sep 8;2004(36):PE34. Review.

17.

A longer and healthier life with TOR down-regulation: genetics and drugs.

Bjedov I, Partridge L.

Biochem Soc Trans. 2011 Apr;39(2):460-5. doi: 10.1042/BST0390460. Review.

PMID:
21428920
18.

LKB1 and AMP-activated protein kinase control of mTOR signalling and growth.

Shaw RJ.

Acta Physiol (Oxf). 2009 May;196(1):65-80. doi: 10.1111/j.1748-1716.2009.01972.x. Epub 2009 Feb 19. Review.

19.

Nutrient-dependent regulation of autophagy through the target of rapamycin pathway.

Chang YY, Juhász G, Goraksha-Hicks P, Arsham AM, Mallin DR, Muller LK, Neufeld TP.

Biochem Soc Trans. 2009 Feb;37(Pt 1):232-6. doi: 10.1042/BST0370232. Review.

PMID:
19143638
20.

AMPK as a Pro-longevity Target.

Burkewitz K, Weir HJ, Mair WB.

EXS. 2016;107:227-256. Review.

PMID:
27812983

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