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Items: 1 to 20 of 37

1.

High-content, image-based screening for drug targets in yeast.

Ohnuki S, Oka S, Nogami S, Ohya Y.

PLoS One. 2010 Apr 14;5(4):e10177. doi: 10.1371/journal.pone.0010177.

2.

Yeast as a tool to uncover the cellular targets of drugs.

Sturgeon CM, Kemmer D, Anderson HJ, Roberge M.

Biotechnol J. 2006 Mar;1(3):289-98. Review.

PMID:
16897709
3.

Yeast and drug discovery.

Hughes TR.

Funct Integr Genomics. 2002 Sep;2(4-5):199-211. Epub 2002 May 31. Review.

PMID:
12192593
4.

Yeast as a drug discovery platform in Huntington's and Parkinson's diseases.

Outeiro TF, Giorgini F.

Biotechnol J. 2006 Mar;1(3):258-69. Review.

PMID:
16897706
6.

Chemical genetics: budding yeast as a platform for drug discovery and mapping of genetic pathways.

Enserink JM.

Molecules. 2012 Aug 2;17(8):9258-73. doi: 10.3390/molecules17089258. Review.

7.

Yeast cells as tools for target-oriented screening.

Munder T, Hinnen A.

Appl Microbiol Biotechnol. 1999 Sep;52(3):311-20. Review.

PMID:
10531642
8.

Yeast genomics and drug target identification.

Bharucha N, Kumar A.

Comb Chem High Throughput Screen. 2007 Sep;10(8):618-34. Review.

PMID:
18045076
9.

The utility of yeast as a tool for cell-based, target-directed high-throughput screening.

Norcliffe JL, Alvarez-Ruiz E, Martin-Plaza JJ, Steel PG, Denny PW.

Parasitology. 2014 Jan;141(1):8-16. doi: 10.1017/S0031182013000425. Epub 2013 Apr 24. Review.

PMID:
23611102
10.

Yeast models of human mitochondrial diseases: from molecular mechanisms to drug screening.

Schwimmer C, Rak M, Lefebvre-Legendre L, Duvezin-Caubet S, Plane G, di Rago JP.

Biotechnol J. 2006 Mar;1(3):270-81. Review.

PMID:
16897707
11.

Combining functional genomics and chemical biology to identify targets of bioactive compounds.

Ho CH, Piotrowski J, Dixon SJ, Baryshnikova A, Costanzo M, Boone C.

Curr Opin Chem Biol. 2011 Feb;15(1):66-78. doi: 10.1016/j.cbpa.2010.10.023. Epub 2010 Nov 17. Review.

PMID:
21093351
12.

Yeast system as a screening tool for pharmacological assessment of g protein coupled receptors.

Minic J, Sautel M, Salesse R, Pajot-Augy E.

Curr Med Chem. 2005;12(8):961-9. Review.

PMID:
15853708
13.

Yeast chemical genomics and drug discovery: an update.

Hoon S, St Onge RP, Giaever G, Nislow C.

Trends Pharmacol Sci. 2008 Oct;29(10):499-504. doi: 10.1016/j.tips.2008.07.006. Epub 2008 Aug 26. Review.

PMID:
18755517
14.

Chemical-genetic approaches for exploring the mode of action of natural products.

Lopez A, Parsons AB, Nislow C, Giaever G, Boone C.

Prog Drug Res. 2008;66:237, 239-71. Review.

PMID:
18416308
15.

Contributions of Saccharomyces cerevisiae to understanding mammalian gene function and therapy.

Zhang N, Bilsland E.

Methods Mol Biol. 2011;759:501-23. doi: 10.1007/978-1-61779-173-4_28. Review.

PMID:
21863505
16.

Label-free screening assays: a strategy for finding better drug candidates.

Lunn CA.

Future Med Chem. 2010 Nov;2(11):1703-16. doi: 10.4155/fmc.10.246. Review.

PMID:
21428840
17.

Genomic and genetic approaches for the identification of antifungal drug targets.

Agarwal AK, Xu T, Jacob MR, Feng Q, Li XC, Walker LA, Clark AM.

Infect Disord Drug Targets. 2008 Mar;8(1):2-15. Review.

PMID:
18473903
18.

Genetic interventions in mammalian cells; applications and uses in high-throughput screening and drug discovery.

Hampton SL, Kinnaird AI.

Cell Biol Toxicol. 2010 Feb;26(1):43-55. doi: 10.1007/s10565-009-9140-z. Epub 2009 Nov 11. Review.

PMID:
19904619
19.

Chemical genomics and emerging DNA technologies in the identification of drug mechanisms and drug targets.

Olsen LC, Færgeman NJ.

Curr Top Med Chem. 2012;12(12):1331-45. Review.

PMID:
22690680
20.

Technological advances in high-throughput screening.

Fernandes PB.

Curr Opin Chem Biol. 1998 Oct;2(5):597-603. Review.

PMID:
9818185

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