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Items: 1 to 20 of 68

1.

Multiple roles of BRIT1/MCPH1 in DNA damage response, DNA repair, and cancer suppression.

Lin SY, Liang Y, Li K.

Yonsei Med J. 2010 May;51(3):295-301. doi: 10.3349/ymj.2010.51.3.295. Review.

2.

DNA damage response pathways in tumor suppression and cancer treatment.

Liang Y, Lin SY, Brunicardi FC, Goss J, Li K.

World J Surg. 2009 Apr;33(4):661-6. doi: 10.1007/s00268-008-9840-1. Review.

PMID:
19034564
3.

BRIT1/MCPH1: a guardian of genome and an enemy of tumors.

Chaplet M, Rai R, Jackson-Bernitsas D, Li K, Lin SY.

Cell Cycle. 2006 Nov;5(22):2579-83. Review.

PMID:
17172830
4.

Emerging roles of MCPH1: expedition from primary microcephaly to cancer.

Venkatesh T, Suresh PS.

Eur J Cell Biol. 2014 Mar;93(3):98-105. doi: 10.1016/j.ejcb.2014.01.005. Review.

PMID:
24560403
5.

DNA damage tumor suppressor genes and genomic instability.

Motoyama N, Naka K.

Curr Opin Genet Dev. 2004 Feb;14(1):11-6. Review.

PMID:
15108799
6.

Therapeutic exploitation of tumor cell defects in homologous recombination.

Powell SN, Kachnic LA.

Anticancer Agents Med Chem. 2008 May;8(4):448-60. Review.

PMID:
18473729
7.

The DNA damage response molecule MCPH1 in brain development and beyond.

Liu X, Zhou ZW, Wang ZQ.

Acta Biochim Biophys Sin (Shanghai). 2016 Jul;48(7):678-85. doi: 10.1093/abbs/gmw048. Review.

PMID:
27197793
8.

The ATM-Chk2 and ATR-Chk1 pathways in DNA damage signaling and cancer.

Smith J, Tho LM, Xu N, Gillespie DA.

Adv Cancer Res. 2010;108:73-112. doi: 10.1016/B978-0-12-380888-2.00003-0. Review.

PMID:
21034966
9.

ATM and ATR as therapeutic targets in cancer.

Weber AM, Ryan AJ.

Pharmacol Ther. 2015 May;149:124-38. doi: 10.1016/j.pharmthera.2014.12.001. Review.

10.

RAP80 and RNF8, key players in the recruitment of repair proteins to DNA damage sites.

Yan J, Jetten AM.

Cancer Lett. 2008 Nov 28;271(2):179-90. doi: 10.1016/j.canlet.2008.04.046. Review.

11.

Targeting the microRNA-regulating DNA damage/repair pathways in cancer.

Bottai G, Pasculli B, Calin GA, Santarpia L.

Expert Opin Biol Ther. 2014 Nov;14(11):1667-83. doi: 10.1517/14712598.2014.950650. Review.

PMID:
25190496
12.

ERK kinases modulate the activation of PI3 kinase related kinases (PIKKs) in DNA damage response.

Lin X, Yan J, Tang D.

Histol Histopathol. 2013 Dec;28(12):1547-54. doi: 10.14670/HH-28.1547. Review.

PMID:
23832672
13.

DNA damage response as an anti-cancer barrier: damage threshold and the concept of 'conditional haploinsufficiency'.

Bartek J, Lukas J, Bartkova J.

Cell Cycle. 2007 Oct 1;6(19):2344-7. Review.

PMID:
17700066
14.

DNA damage response--a double-edged sword in cancer prevention and cancer therapy.

Tian H, Gao Z, Li H, Zhang B, Wang G, Zhang Q, Pei D, Zheng J.

Cancer Lett. 2015 Mar 1;358(1):8-16. doi: 10.1016/j.canlet.2014.12.038. Review.

PMID:
25528631
15.

DNA damage response and prostate cancer: defects, regulation and therapeutic implications.

Karanika S, Karantanos T, Li L, Corn PG, Thompson TC.

Oncogene. 2015 May 28;34(22):2815-22. doi: 10.1038/onc.2014.238. Review.

16.

Importance of DNA damage checkpoints in the pathogenesis of human cancers.

Poehlmann A, Roessner A.

Pathol Res Pract. 2010 Sep 15;206(9):591-601. doi: 10.1016/j.prp.2010.06.006. Review.

PMID:
20674189
17.

An unconventional role of BMP-Smad1 signaling in DNA damage response: a mechanism for tumor suppression.

Liu H, Bao D, Xia X, Chau JF, Li B.

J Cell Biochem. 2014 Mar;115(3):450-6. doi: 10.1002/jcb.24698. Review.

PMID:
24142423
18.

The role of NBS1 in the modulation of PIKK family proteins ATM and ATR in the cellular response to DNA damage.

Zhou J, Lim CU, Li JJ, Cai L, Zhang Y.

Cancer Lett. 2006 Nov 8;243(1):9-15. Review.

19.

The ATM-dependent DNA damage signaling pathway.

Kitagawa R, Kastan MB.

Cold Spring Harb Symp Quant Biol. 2005;70:99-109. Review.

PMID:
16869743
20.

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